Search Results

Presence of CYP2C9*3 allele increases risk for hypoglycemia in Type 2 diabetic patients treated with sulfonylureas

Authors: Ragia, Georgia; Petridis, Ioannis; Tavridou, Anna; Christakidis, Dimitrios; Manolopoulos, Vangelis G

Source: Pharmacogenomics, Volume 10, Number 11, November 2009 , pp. 1781-1787(7)

Publisher: Future Medicine

Editorial [Special Board Members Issue]

Author: Prakash, Chandra

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 659-660(2)

Publisher: Bentham Science Publishers

Oxidation of Endobiotics Mediated by Xenobiotic-Metabolizing Forms of Human Cytochrome P450

Authors: Niwa, Toshiro; Murayama, Norie; Yamazaki, Hiroshi

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 700-712(13)

Publisher: Bentham Science Publishers

Mitochondrial gene profiling: translational perspectives

Authors: Johnston, Daniel S; Su, Yan A; Alesci, Salvatore

Source: Pharmacogenomics, Volume 10, Number 10, October 2009 , pp. 1645-1655(11)

Publisher: Future Medicine

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance: Part I

Author: Zhou, Shu-Feng

Source: Clinical Pharmacokinetics, Volume 48, Number 11, 1 November 2009 , pp. 689-723(35)

Publisher: Adis International

Site of metabolism prediction for six biotransformations mediated by cytochromes P450

Authors: Zheng, Mingyue; Luo, Xiaomin; Shen, Qiancheng; Wang, Yong; Du, Yun; Zhu, Weiliang; Jiang, Hualiang

Source: Bioinformatics, Volume 25, Number 10, 15 May 2009 , pp. 1251-1258(8)

Publisher: Oxford University Press

Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity

Authors: Nucci, Gianluca; Gomeni, Roberto; Poggesi, Italo

Source: Expert Opinion on Drug Discovery, Volume 4, Number 8, August 2009 , pp. 837-856(20)

Publisher: Informa Healthcare

Utilization of estimated physicochemical properties as an integrated part of predicting hepatic clearance in the early drug-discovery stage: Impact of plasma and microsomal binding

Authors: Emoto, C.; Murayama, N.; Rostami-Hodjegan, A.; Yamazaki, H.

Source: Xenobiotica, Volume 39, Number 3, March 2009 , pp. 227-235(9)

Publisher: Informa Healthcare

Assays to Predict Drug Permeation Across the Blood-Brain Barrier, and Distribution to Brain

Authors: Abbott, N. J.; Dolman, D. E.M.; Patabendige, A. K.

Source: Current Drug Metabolism, Volume 9, Number 9, November 2008 , pp. 901-910(10)

Publisher: Bentham Science Publishers

Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays

Authors: Houston, J. B.; Galetin, Aleksandra

Source: Current Drug Metabolism, Volume 9, Number 9, November 2008 , pp. 940-951(12)

Publisher: Bentham Science Publishers

A Survey on Recent Patents of Biological Pathway Based on Computational Methods

Authors: Zhang, Chen; Du, Wei; Shi, Xiaohu; Wang, Yan; Wang, Shuqin; Zheng, Shanhong; Zhou, Chunguang; Liang, Yanchun

Source: Recent Patents on DNA & Gene Sequences, Volume 2, Number 3, November 2008 , pp. 200-208(9)

Publisher: Bentham Science Publishers

Impact of Genetic Polymorphisms on the Efficacy of HMG-CoA Reductase Inhibitors

Authors: Hutz, Mara H.; Fiegenbaum, Marilu

Source: American Journal of Cardiovascular Drugs, Volume 8, Number 3, 2008 , pp. 161-170(10)

Publisher: Adis International

Potential of Pharmacokinetic Profiling for Detecting Herbal Interactions with Drugs

Authors: Butterweck, Veronika; Derendorf, Hartmut

Source: Clinical Pharmacokinetics, Volume 47, Number 6, 2008 , pp. 383-397(15)

Publisher: Adis International

Prediction of human pharmacokinetics—biliary and intestinal clearance and enterohepatic circulation

Author: Fagerholm, Urban

Source: Journal of Pharmacy and Pharmacology, Volume 60, Number 5, May 2008 , pp. 535-542(8)

Publisher: Pharmaceutical Press

Recent Advances in the In Silico Modelling of UDP Glucuronosyltransferase Substrates

Authors: Sorich, Michael J.; Smith, Paul A.; Miners, John O.; Mackenzie, Peter I.; McKinnon, Ross A.

Source: Current Drug Metabolism, Volume 9, Number 1, January 2008 , pp. 60-69(10)

Publisher: Bentham Science Publishers

Relationship between expression of 5-fluorouracil metabolic enzymes and 5-fluorouracil sensitivity in esophageal carcinoma cell lines

Authors: Ando, T.; Ishiguro, H.; Kuwabara, Y.; Kimura, M.; Mitsui, A.; Sugito, N.; Mori, R.; Ogawa, R.; Katada, T.; Fujii, Y.

Source: Diseases of the Esophagus, Volume 21, Number 1, February 2008 , pp. 15-20(6)

Publisher: Blackwell Publishing

In vitro-in vivo extrapolation of hepatic clearance: Biological tools, scaling factors, model assumptions and correct concentrations

Authors: Pelkonen, O.; Turpeinen, M.

Source: Xenobiotica, Volume 37, Numbers 10-11, October 2007 , pp. 1066-1089(24)

Publisher: Informa Healthcare

Improving Early Drug Discovery through ADME Modelling: An Overview

Author: Wishart, David S.

Source: Drugs in R&D, Volume 8, Number 6, 2007 , pp. 349-362(14)

Publisher: Adis International

Designing Drugs on the Internet? Free Web Tools and Services Supporting Medicinal Chemistry

Authors: Ertl, Peter; Jelfs, Stephen

Source: Current Topics in Medicinal Chemistry, Volume 7, Number 15, August 2007 , pp. 1491-1501(11)

Publisher: Bentham Science Publishers

Prediction of human pharmacokinetics - renal metabolic and excretion clearance

Author: Fagerholm, Urban

Source: Journal of Pharmacy and Pharmacology, Volume 59, Number 11, November 2007 , pp. 1463-1471(9)

Publisher: Pharmaceutical Press