Search Results

Distinct mechanistic activity profile of pralatrexate in comparison to other antifolates in in vitro and in vivo models of human cancers

Authors: Izbicka, E.; Diaz, A.; Streeper, R.; Wick, M.; Campos, D.; Steffen, R.; Saunders, M.

Source: Cancer Chemotherapy and Pharmacology, Volume 64, Number 5, October 2009 , pp. 993-999(7)

Publisher: Springer

Post-translational modifications of tubulin in the nervous system

Authors: Fukushima, Nobuyuki; Furuta, Daisuke; Hidaka, Yuji; Moriyama, Ryutaro; Tsujiuchi, Toshifumi

Source: Journal of Neurochemistry, Volume 109, Number 3, May 2009 , pp. 683-693(11)

Publisher: Blackwell Publishing

Recent Advances in Classical and Non-Classical Antifolates as Antitumor and Antiopportunistic Infection Agents: Part II

Authors: Gangjee, Aleem; Jain, Hiteshkumar D.; Kurup, Sonali

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 2, February 2008 , pp. 205-231(27)

Publisher: Bentham Science Publishers

Recent Advances in Classical and Non-Classical Antifolates as Antitumor and Antiopportunistic Infection Agents: Part I

Authors: Gangjee, Aleem; Jain, Hiteshkumar D.; Kurup, Sonali

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 7, Number 5, September 2007 , pp. 524-542(19)

Publisher: Bentham Science Publishers

Molecular basis of antifolate resistance

Author: Assaraf, Yehuda

Source: Cancer and Metastasis Reviews, Volume 26, Number 1, March 2007 , pp. 153-181(29)

Publisher: Springer

Post-translational modifications of α-tubulin in Zea mays L. are highly tissue specific

Authors: Wang, Wei; Vignani, Rita; Scali, Monica; Sensi, Elisabetta; Cresti, Mauro

Source: Planta, Volume 218, Number 3, January 2004 , pp. 460-465(6)

Publisher: Springer

Effect of polyglutamylation of methotrexate on its accumulation and the development of resistance in the protozoan parasite Leishmania

Authors: El Fadili A.; Richard D.; Kundig C.; Ouellette M.

Source: Biochemical Pharmacology, Volume 66, Number 6, 15 September 2003 , pp. 999-1008(10)

Publisher: Elsevier

Activity of a Novel Anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against Human Lymphoma is Superior to Methotrexate and Correlates with Tumor RFC-1 Gene Expression

Authors: Eunice S. Wang; Owen O'Connor; Yuhong She; Andrew D. Zelenetz; F.M. Sirotnak; Malcolm A.S. Moore

Source: Leukemia and Lymphoma, Volume 44, Number 6, 2003 , pp. 1027-1035(9)

Publisher: Informa Healthcare

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis

Authors: Hooijberg J.H.; Peters G.J.; Assaraf Y.G.; Kathmann I.; Priest D.G.; Bunni M.A.; Veerman A.J.P.; Scheffer G.L.; Kaspers G.J.L.; Jansen G.

Source: Biochemical Pharmacology, Volume 65, Number 5, 1 March 2003 , pp. 765-771(7)

Publisher: Elsevier

Characterization of the folylpolyglutamate synthetase gene and polyglutamylation of folates in the protozoan parasite Leishmania

Authors: Fadili A.E.; Kundig C.; Ouellette M.

Source: Molecular and Biochemical Parasitology, Volume 124, Number 1, 10 September 2002 , pp. 63-71(9)

Publisher: Elsevier

Interaction of STOP with neuronal tubulin is independent of polyglutamylation

Authors: Bonnet C.; Denarier E.; Bosc C.; Lazereg S.; Denoulet P.; Larcher J-C.

Source: Biochemical and Biophysical Research Communications, Volume 297, Number 4, October 2002 , pp. 787-793(7)

Publisher: Academic Press

The Means to an End of Tumor Cell Resistance to Chemotherapeutic Drugs Targeting Thymidylate Synthase: Shoot the Messenger

Authors: Berg R.W.; Ferguson P.J.; DeMoor J.M.; Vincent M.D.; Vincent M.D.; Koropatnick J.

Source: Current Drug Targets, Volume 3, Number 4, August 2002 , pp. 297-309(13)

Publisher: Bentham Science Publishers

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

Authors: Banerjee D.; Mayer-Kuckuk P.; Capiaux G.; Budak-Alpdogan T.; Gorlick R.; Bertino J.R.

Source: Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease, Volume 1587, Number 2, 18 July 2002 , pp. 164-173(10)

Publisher: Elsevier

Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

Authors: Peters G.J.; Backus H.H.J.; Freemantle S.; van Triest B.; Codacci-Pisanelli G.; van der Wilt C.L.; Smid K.; Lunec J.; Calvert A.H.; Marsh S.; McLeod H.L.; Bloemena E.; Meijer S.; Jansen G.; van Groeningen C.J.; Pinedo H.M.

Source: Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease, Volume 1587, Number 2, 18 July 2002 , pp. 194-205(12)

Publisher: Elsevier

Recent Advances in the Chemistry and Biology of Folypoly--glutamate Synthetase Substrates and Inhibitors

Authors: Gangjee A.; Dubash N.P.; Zeng Y.; McGuire J.J.

Source: Current Medicinal Chemistry - Anti-Cancer Agents, Volume 2, Number 3, May 2002 , pp. 331-355(25)

Publisher: Bentham Science Publishers

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis

Authors: Mauritz R.; Peters G.J.; Priest D.G.; Assaraf Y.G.; Drori S.; Kathmann I.; Noordhuis P.; Bunni M.A.; Rosowsky A.; Schornagel J.H.; Pinedo H.M.; Jansen G.

Source: Biochemical Pharmacology, Volume 63, Number 2, 15 January 2002 , pp. 105-115(11)

Publisher: Elsevier

Basal body replication in green algae – when and where does it start?

Authors: Lechtreck K-F.; Bornens M.

Source: European Journal of Cell Biology, Volume 80, Number 10, October 2001 , pp. 631-641(11)

Publisher: Urban & Fischer

Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia

Authors: Rots, Marianne G.; Pieters, Rob; Peters, Godefridus J.; Noordhuis, Paul; Van Zantwijk, Christina H.; Henze, Günter; Janka-Schaub, Gritta E.; Veerman, Anjo J. P.; Jansen, Gerrit

Source: British Journal of Haematology, Volume 109, Number 3, June 2000 , pp. 629-634(6)

Publisher: Blackwell Publishing

Cytoskeleton: Functions for tubulin modifications at last

Author: Rosenbaum J.

Source: Current Biology, Volume 10, Number 21, 1 November 2000 , pp. 801-803(3)

Publisher: Elsevier

Two promoters regulate transcription of the mouse folylpolyglutamate synthetase gene Three tightly clustered Sp1 sites within the first intron markedly enhance activity of promoter B

Authors: Chen J.; Hayes P.; Roy K.; Sirotnak F.M.

Source: Gene, Volume 242, Number 1, 25 January 2000 , pp. 257-264(8)

Publisher: Elsevier