Search Results

Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D^−/−) mice

Authors: Rutten, Kris; Misner, Dinah L.; Works, Melissa; Blokland, Arjan; Novak, Thomas J.; Santarelli, Luca; Wallace, Tanya L.

Source: European Journal of Neuroscience, Volume 28, Number 3, August 2008 , pp. 625-632(8)

Publisher: Blackwell Publishing

Stroke genetics - focus on PDE4D gene

Authors: Munshi, Anjana; Kaul, Subhash

Source: International Journal of Stroke, Volume 3, Number 3, August 2008 , pp. 188-192(5)

Publisher: Blackwell Publishing

Association of phosphodiesterase 4D gene G0 haplotype and ischaemic stroke in a Greek population

Authors: Fidani, L.; Clarimon, J.; Goulas, A.; Hatzitolios, A. I.; Evans, W.; Tsirogianni, E.; Hardy, J.; Kotsis, A.

Source: European Journal of Neurology, Volume 14, Number 7, July 2007 , pp. 745-749(5)

Publisher: Blackwell Publishing

The phosphodiesterase 4D gene for early onset ischemic stroke among normotensive patients

Authors: LIN, H.-F.; LIAO, Y.-C.; LIOU, C.-W.; LIU, C.-K.; JUO, S.-H. H.

Source: Journal of Thrombosis and Haemostasis, Volume 5, Number 2, February 2007 , pp. 436-438(3)

Publisher: Blackwell Publishing

Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study

Authors: Song, Qing; Cole, John W.; Stine, Oscar C.; Gallagher, Margaret; Giles, Wayne H.; Mitchell, Braxton D.; Wozniak, Marcella A.; Stern, Barney J.; Sorkin, John D.; McArdle, Patrick F.; Naj, Adam C.; Xu, Qin; Gibbons, Gary H.; Kittner, Steven J.

Source: Human Molecular Genetics, Volume 15, Number 16, 15 August 2006 , pp. 2468-2478(11)

Publisher: Oxford University Press

Phosphodiesterase 4D and heart failure: a cautionary tale

Authors: Lehnart, Stephan E; Marks, Andrew R

Source: Expert Opinion on Therapeutic Targets, Volume 10, Number 5, October 2006 , pp. 677-688(12)

Publisher: Informa Healthcare

Regulation of cAMP-specific phosphodiesterases type 4B and 4D (PDE4) splice variants by cAMP signaling in primary cortical neurons

Authors: D'Sa, Carrol; Tolbert, Lara M.; Conti, Marco; Duman, Ronald S.

Source: Journal of Neurochemistry, Volume 81, Number 4, May 2002 , pp. 745-757(13)

Publisher: Blackwell Publishing

4D or not 4D - the emetogenic basis of PDE4 inhibitors uncovered?

Author: Giembycz M.A.

Source: Trends in Pharmacological Sciences, Volume 23, Number 12, 1 December 2002 , pp. 548-548(1)

Publisher: Elsevier

Antidepressant-like Profile and Reduced Sensitivity to Rolipram in Mice Deficient in the PDE4D Phosphodiesterase Enzyme

Authors: Zhang H.-T.; Huang Y.; Jin S.-L.C.; Frith S.A.; Suvarna N.; Conti M.; O'Donnell J.M.

Source: Neuropsychopharmacology, Volume 27, Number 4, October 2002 , pp. 587-595(9)

Publisher: Elsevier

Crystal structure of phosphodiesterase 4D and inhibitor complex

Authors: Lee M.E.; Markowitz J.; Lee J.-O.; Lee H.

Source: FEBS Letters, Volume 530, Number 1, 23 October 2002 , pp. 53-58(6)

Publisher: Elsevier

Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: a potent and selective phosphodiesterase type 4D inhibitor

Authors: Hersperger R.; Dawson J.; Mueller T.

Source: Bioorganic and Medicinal Chemistry Letters, Volume 12, Number 2, 21 January 2002 , pp. 233-235(3)

Publisher: Elsevier

Phosphodiesterases 4D and 7A Splice Variants in the Response of HUVEC Cells to TNF-¹

Authors: Miro X.; Casacuberta J.M.; Gutierrez-Lopez M.D.; de Landazuri M.O.; Puigdomenech P.

Source: Biochemical and Biophysical Research Communications, Volume 274, Number 2, 2 August 2000 , pp. 415-421(7)

Publisher: Elsevier

Phosphodiesterases 4D and 7A Splice Variants in the Response of HUVEC Cells to TNF-¹

Authors: Miró X.; Casacuberta J.M.; Gutiérrez-López M.D.; de Landázuri M.O.; Puigdomènech P.

Source: Biochemical and Biophysical Research Communications, Volume 274, Number 2, August 2000 , pp. 415-421(7)

Publisher: Academic Press

Nicotinamide derivatives as selective inhibitors of PDE4

Source: Expert Opinion on Therapeutic Patents, Volume 9, Number 4, April 1999 , pp. 481-485(5)

Publisher: Informa Healthcare

Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei

Authors: Lugnier C.; Keravis T.; Le Bec A.; Pauvert O.; Proteau S.; Rousseau E.

Source: Biochimica et Biophysica Acta (BBA)/General Subjects, Volume 1472, Number 3, 16 November 1999 , pp. 431-446(16)

Publisher: Elsevier

Effect of Pregnancy on PDE4 cAMP-Specific Phosphodiesterase Messenger Ribonucleic Acid Expression in Human Myometrium - Human Cell Culture Protocols

Authors: Leroy M.J.; Mehats C.; Duc-Goiran P.; Tanguy G.; Robert B.; Dallot E.; Mignot T.M.; Grange G.; Ferre F.

Source: Cellular Signalling, Volume 11, Number 1, January 1999 , pp. 31-37(7)

Publisher: Elsevier

Effects of Dexamethasone and Glucagon after Long-Term Exposure on Cyclic AMP Phosphodiesterase 4 in Cultured Rat Hepatocytes

Authors: Hermsdorf T.; Richter W.; Dettmer D.

Source: Cellular Signalling, Volume 11, Number 9, September 1999 , pp. 685-690(6)

Publisher: Elsevier

Quinazolines: combined type 3 and 4 phosphodiesterase inhibitors

Authors: Charpiot B.; Brun J.; Donze I.; Naef R.; Stefani M.; Mueller T.

Source: Bioorganic and Medicinal Chemistry Letters, Volume 8, Number 20, 20 October 1998 , pp. 2891-2896(6)

Publisher: Elsevier

Chemical abbreviations are given in the the Materials section of Materials and Methods. Nomenclature for cyclic-nucleotide phosphodiesterase (PDE) genes is taken from the most recent recommendations [3]. Expressed PDE4 protein isoforms (naturally occurring) and forms (cloned variants) are referred to by abbreviations such as A_12CatS, in which A, B, C or D refers to the PDE4 isogene and the subscript refers to the PDE4 domains shown in Figure 1.Comparison of Recombinant Human PDE4 Isoforms - A Laboratory Manual

Authors: SaldouSaldou N.; ObernolteObernolte R.; HuberHuber A.; BaeckerBaecker P.A.; WilhelmWilhelm R.; AlvarezAlvarez R.; LiLi B.; XiaXia L.; CallanCallan O.; SuSu C.; JarnaginJarnagin K.; SheltonShelton E.R.

Source: Cellular Signalling, Volume 10, Number 6, June 1998 , pp. 427-440(14)

Publisher: Elsevier

Effect of a cGMP-specific phosphodiesterase inhibitor on retinal function

Authors: Estrade M.; Grondin P.; Cluzel J.; Bonhomme B.; Doly M.

Source: European Journal of Pharmacology, Volume 352, Number 2, 10 July 1998 , pp. 157-163(7)

Publisher: Elsevier