Search Results

Evaluation of CYP1A1 and CYP2B1/2 m-RNA Induction in Rat Liver Slices Using the NanoString® Technology: A Novel Tool for Drug Discovery Lead Optimization

Authors: Palamanda, Jairam R.; Kumari, Pramila; Murgolo, Nicholas; Benbow, Larry; Lin, Xinjie; Nomeir, Amin A.

Source: Drug Metabolism Letters, Volume 3, Number 3, August 2009 , pp. 171-175(5)

Publisher: Bentham Science Publishers

Comprehensive Assessment of ADMET Risks in Drug Discovery

Author: Wang, Jianling

Source: Current Pharmaceutical Design, Volume 15, Number 19, July 2009 , pp. 2195-2219(25)

Publisher: Bentham Science Publishers

The Role of Hyphenated Chromatography-Mass Spectrometry Techniques in Exploratory Drug Metabolism and Pharmacokinetics

Authors: Hsieh, Yunsheng; Korfmacher, Walter

Source: Current Pharmaceutical Design, Volume 15, Number 19, July 2009 , pp. 2251-2261(11)

Publisher: Bentham Science Publishers

12. Is Product Patent Protection Necessary to Spur Innovation in Developing Countries?

Author: Chaudhuri, Sudip

Source: The Development Agenda, December 2008 , pp. 265-293(29)

Publisher: Oxford Scholarship Online Monographs

Synthetic Approaches to the 2007 New Drugs

Authors: Liu, Kevin K.C.; Sakya, Subas M.; O'Donnell, Christopher J.; Li, Jin

Source: Mini Reviews in Medicinal Chemistry, Volume 8, Number 14, December 2008 , pp. 1526-1548(23)

Publisher: Bentham Science Publishers

The Preclinical Testing Strategy for the Development of Novel Chemical Entities for the Treatment of Asthma

Authors: Hahn, Christian; Erb, Klaus J.

Source: Current Drug Targets, Volume 9, Number 6, June 2008 , pp. 443-451(9)

Publisher: Bentham Science Publishers

Strategies to In Vitro Assessment of Major Human CYP Enzyme Activities by Using Liquid Chromatography Tandem Mass Spectrometry

Authors: Lahoz, A.; Donato, M. T.; Castell, J. V.; Gomez-Lechon, M. J.

Source: Current Drug Metabolism, Volume 9, Number 1, January 2008 , pp. 12-19(8)

Publisher: Bentham Science Publishers

Synthetic Approaches to the 2006 New Drugs

Authors: Liu, Kevin K.C.; Sakya, Subas M.; Li, Jin

Source: Mini Reviews in Medicinal Chemistry, Volume 7, Number 12, December 2007 , pp. 1255-1269(15)

Publisher: Bentham Science Publishers

Economic Evaluation of a Bayesian Model to Predict Late-Phase Success of New Chemical Entities

Authors: Schachter, Asher D.; Ramoni, Marco F.; Baio, Gianluca; Roberts, Thomas G.; Finkelstein, Stanley N.

Source: Value in Health, Volume 10, Number 5, September/October 2007 , pp. 377-385(9)

Publisher: Blackwell Publishing

Synthetic Approaches to the 2005 New Drugs

Authors: Sakya, Subas M.; Li, Jin; Liu, Kevin K.C.

Source: Mini Reviews in Medicinal Chemistry, Volume 7, Number 4, April 2007 , pp. 429-450(22)

Publisher: Bentham Science Publishers

EDITORIAL

Author: Prakash, Chandra

Source: Drug Metabolism Letters, Volume 1, Number 1, January 2007 , pp. 1-1(1)

Publisher: Bentham Science Publishers

In Vitro ADME Medium/High-Throughput Screening in Drug Preclinical Development

Authors: Lahoz, A.; Gombau, L.; Donato, M. T.; V Castell, J.; Gomez-Lechon, M. J.

Source: Mini Reviews in Medicinal Chemistry, Volume 6, Number 9, September 2006 , pp. 1053-1062(10)

Publisher: Bentham Science Publishers

Investigation of Drug-Induced Mitochondrial Toxicity Using Fluorescence-Based Oxygen-Sensitive Probes

Authors: Hynes, James; Marroquin, Lisa D.; Christiansen, Katerina N.; Stevens, Gregory J.; Papkovsky, Dmitri B.; Will, Yvonne

Source: Toxicological Sciences, Volume 92, Number 1, July 2006 , pp. 186-200(15)

Publisher: Oxford University Press

Development potential of rifalazil and other benzoxazinorifamycins

Authors: Rothstein, David M; Shalish, Christo; Murphy, Christopher K; Sternlicht, Andrew; Campbell, Lee Ann

Source: Expert Opinion on Investigational Drugs, Volume 15, Number 6, June 2006 , pp. 603-623(21)

Publisher: Informa Healthcare

Synthetic Approaches to the 2004 New Drugs

Authors: Li, Jin; Liu, Kevin K.C.; Sakya, Subas

Source: Mini Reviews in Medicinal Chemistry, Volume 5, Number 12, December 2005 , pp. 1133-1144(12)

Publisher: Bentham Science Publishers

Experimental and Virtual Physicochemical and Pharmacokinetic Profiling of New Chemical Entities

Authors: Martel, Sophie; Castella, Marc-Etienne; Bajot, Fania; Ottaviani, Giorgio; Bard, Bruno; Henchoz, Yveline; Valloton, Bénédicte Gross; Reist, Marianne; Carrupt, Pierre-Alain

Source: CHIMIA International Journal for Chemistry, Volume 59, Number 6, June 2005 , pp. 308-314(7)

Publisher: Swiss Chemical Society

Characterization of ₃-adrenergic receptor: determination of pharmacophore and 3D QSAR model for ₃ adrenergic receptor agonism

Authors: Prathipati, Philip; Saxena, Anil

Source: Journal of Computer-Aided Molecular Design, Volume 19, Number 2, February 2005 , pp. 93-110(18)

Publisher: Springer

Current Status of Short-Term Tests for Evaluation of Genotoxicity, Mutagenicity, and Carcinogenicity of Environmental Chemicals and NCEs

Authors: Bajpayee, Mahima; Pandey, Alok; Parmar, Devendra; Dhawan, Alok

Source: Toxicology Mechanisms and Methods, Volume 15, Number 3, May-June 2005 , pp. 155-180(26)

Publisher: Informa Healthcare

Utilisation of Human Pharmacology Studies with Biomarkers for New Drug Applications in Japan

Authors: Yasuo Kodama; Kazuyuki Saito; Shunsuke Ono; Hirofumi Kodama; Masae Kuranari; Kimiko Tsutsumi; Deborah F. Yaplee; Hiromi Takano-Ohmuro; Mizue Mutoh; Akio Fujimura

Source: Drugs in R&D, Volume 6, Number 1, 2005 , pp. 21-34(14)

Publisher: Adis International

Pharmaceutical Pricing and Reimbursement Strategies Over the Whole Product Life Cycle: Practical Considerations

Author: Lovatt, Brian

Source: International Journal of Pharmaceutical Medicine, Volume 18, Number 6, 2004 , pp. 343-347(5)

Publisher: Adis International