Search Results

Allometric scaling of clearance in dogs

Authors: MARTINEZ, M.; MAHMOOD, I.; HUNTER, R. P.

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 32, Number 5, October 2009 , pp. 411-416(6)

Publisher: Blackwell Publishing

Pharmacokinetic allometric scaling of coagulation factors and tissue-type plasminogen activators

Author: MAHMOOD, I.

Source: Haemophilia, Volume 15, Number 5, September 2009 , pp. 1109-1117(9)

Publisher: Blackwell Publishing

Physiologically based pharmacokinetics (PBPK)

Authors: Espié, Pascal; Tytgat, Dominique; Sargentini-Maier, Maria-Laura; Poggesi, Italo; Watelet, Jean-Baptiste

Source: Drug Metabolism Reviews, Volume 41, Number 3, August 2009 , pp. 391-407(17)

Publisher: Informa Healthcare

Interspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data

Authors: Ahlawat, P.; Srinivas, N. R.

Source: Xenobiotica, Volume 38, Number 11, November 2008 , pp. 1377-1385(9)

Publisher: Informa Healthcare

Deriving a Data-Based Interspecies Assessment Factor Using the NOAEL and the Benchmark Dose Approach

Authors: Bokkers, Bas G.H.; Slob, Wout

Source: Critical Reviews in Toxicology, Volume 37, Number 5, May 2007 , pp. 355-373(19)

Publisher: Informa Healthcare

Animal-to-Human Extrapolation of the Pharmacokinetic and Pharmacodynamic Properties of Buprenorphine

Authors: Yassen, Ashraf; Olofsen, Erik; Kan, Jingmin; Dahan, Albert; Danhof, Meindert

Source: Clinical Pharmacokinetics, Volume 46, Number 5, 2007 , pp. 433-447(15)

Publisher: Adis International

Allometric scaling, metabolic body size and interspecies comparisons of basal nutritional requirements

Author: Rucker, R. B.

Source: Journal of Animal Physiology and Animal Nutrition, Volume 91, Numbers 3-4, April 2007 , pp. 148-156(9)

Publisher: Blackwell Publishing

Interspecies allometric scaling. Part I: prediction of clearance in large animals

Authors: MAHMOOD, I.; MARTINEZ, M.; HUNTER, R. P.

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 29, Number 5, October 2006 , pp. 415-423(9)

Publisher: Blackwell Publishing

Interspecies allometric scaling: prediction of clearance in large animal species: Part II: mathematical considerations

Authors: MARTINEZ, M.; MAHMOOD, I.; HUNTER, R. P.

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 29, Number 5, October 2006 , pp. 425-432(8)

Publisher: Blackwell Publishing

Modeling and allometric scaling of s(+)-ketoprofen pharmacokinetics and pharmacodynamics: a retrospective analysis

Authors: E.-I. Lepist; W. J. Jusko

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 27, Number 4, August 2004 , pp. 211-218(8)

Publisher: Blackwell Publishing

Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling

Authors: Kirman C.R.; Sweeney L.M.; Meek M.E.; Gargas M.L.

Source: Regulatory Toxicology and Pharmacology, Volume 38, Number 3, December 2003 , pp. 345-367(23)

Publisher: Elsevier

SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. II: In vitro and in vivo metabolism studies and pharmacokinetic extrapolation to man

Authors: Ward K. W.; Proksch J. W.; Gorycki P. D.; Yu C.-P.; Ho M. Y. K.; Bush B. D.; Levy M. A.; Smith B. R.

Source: Xenobiotica, Volume 32, Number 3, 1 March 2002 , pp. 235-250(16)

Publisher: Informa Healthcare

Categorical Default Uncertainty Factors-Interspecies Variation and Adequacy of Database

Author: Meek, M.E. (Bette)

Source: Human and Ecological Risk Assessment, Volume 7, Number 1, January 2001 , pp. 157-163(7)

Publisher: Taylor and Francis Ltd

Pharmacokinetics and interspecies scaling of a novel VEGF receptor inhibitor, SU5416

Authors: Sukbuntherng J.; Cropp G.; Hannah A.; Wagner G.S.; Shawver L.K.; Antonian L.

Source: Journal of Pharmacy and Pharmacology, Volume 53, Number 12, 1 December 2001 , pp. 1629-1636(8)

Publisher: Pharmaceutical Press

Fractal Volume of Drug Distribution: It Scales Proportionally to Body Mass

Authors: Karalis V.; Claret L.; Iliadis A.; Macheras P.

Source: Pharmaceutical Research, Volume 18, Number 7, July 2001 , pp. 1056-1060(5)

Publisher: Springer

The Use of In Vitro Methods to Predict In Vivo Pharmacokinetics and Drug Interactions

Authors: Bachmann K.A.; Ghosh R.

Source: Current Drug Metabolism, Volume 2, Number 3, September 2001 , pp. 299-314(16)

Publisher: Bentham Science Publishers

Computer-assisted drug development (CADD): an emerging technology for designing first-time-in-man and proof-of-concept studies from preclinical experiments

Authors: Gomeni R.; Bani M.; D'Angeli C.; Corsi M.; Bye A.

Source: European Journal of Pharmaceutical Sciences, Volume 13, Number 3, June 2001 , pp. 261-270(10)

Publisher: Elsevier

Allometric Pharmacokinetic Scaling: Towards the Prediction of Human Oral Pharmacokinetics

Authors: Feng M.R.; Lou X.; Brown R.R.; Hutchaleelaha A.

Source: Pharmaceutical Research, Volume 17, Number 4, April 2000 , pp. 410-418(9)

Publisher: Springer

Clearance of Fentanyl, Alfentanil, Methohexitone, Thiopentone and Ketamine in Relation to Estimated Hepatic Blood Flow in Several Animal Species: Application to Prediction of Clearance in Man

Authors: Björkman S.; Redke* F.

Source: Journal of Pharmacy and Pharmacology, Volume 52, Number 9, 1 September 2000 , pp. 1065-1074(10)

Publisher: Pharmaceutical Press

Prediction of Hepatic Metabolic Clearance Based on Interspecies Allometric Scaling Techniques and In Vitro-In Vivo Correlations

Authors: Lavé T.; Coassolo P.; Reigner B.

Source: Clinical Pharmacokinetics, Volume 36, Number 3, March 1999 , pp. 211-231(21)

Publisher: Adis International