Search Results

Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-α

Authors: Onnis, Valeria; Kinsella, Gemma K; Carta, Giorgio; Fayne, Darren; Lloyd, David G

Source: Future Medicinal Chemistry, Volume 1, Number 3, June 2009 , pp. 483-499(17)

Publisher: Future Science

High-throughput siRNA silencing screens to identify host-cell factors required for virus infection

Authors: Mercer, Jason; Helenius, Ari

Source: Future Virology, Volume 4, Number 6, November 2009 , pp. 517-519(3)

Publisher: Future Medicine

Assays for Identification of Hsp90 Inhibitors and Biochemical Methods for Discriminating their Mechanism of Action

Authors: Matts, Robert L.; Manjarrez, Jacob R.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1462-1478(17)

Publisher: Bentham Science Publishers

Phenotypic screening of phylomer peptide libraries derived from genome fragments to identify and validate new targets and therapeutics

Author: Watt, Paul M

Source: Future Medicinal Chemistry, Volume 1, Number 2, May 2009 , pp. 257-265(9)

Publisher: Future Science

Small-Molecule Modulators of the NF-κB Pathway Newly Identified by a Translocation-Based Cellular Assay

Authors: Xie, Yuli; Rinderspacher, Alison; Liu, Yidong; Gong, Gangli; Smith, Deborah H.; Wyler, Michael; Branden, Lars; Deng, Shi-Xian

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 13, September 2009 , pp. 1172-1180(9)

Publisher: Bentham Science Publishers

Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification

Authors: Aouida, Mustapha; Khodami-Pour, Ali; Ramotar, Dindial

Source: Biochemistry and Cell Biology, Volume 87, Number 4, 1 August 2009 , pp. 653-661(9)

Publisher: NRC Research Press

Functional Genomic Approaches Targeting the Wnt Signaling Network

Author: DasGupta, Ramanuj

Source: Current Drug Targets, Volume 10, Number 7, July 2009 , pp. 620-631(12)

Publisher: Bentham Science Publishers

Antifungal Drug Discovery through the Study of Invertebrate Model Hosts

Authors: Pukkila-Worley, R.; Holson, E.; Wagner, F.; Mylonakis, E.

Source: Current Medicinal Chemistry, Volume 16, Number 13, May 2009 , pp. 1588-1595(8)

Publisher: Bentham Science Publishers

RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens

Authors: Rieber, Nora; Knapp, Bettina; Eils, Roland; Kaderali, Lars

Source: Bioinformatics, Volume 25, Number 5, 1 March 2009 , pp. 678-679(2)

Publisher: Oxford University Press

Enhanced gene trapping in mouse embryonic stem cells

Authors: Schnütgen, Frank; Hansen, Jens; De-Zolt, Silke; Horn, Carsten; Lutz, Marcus; Floss, Thomas; Wurst, Wolfgang; Noppinger, Patricia Ruiz; von Melchner, Harald

Source: Nucleic Acids Research, Volume 36, Number 20, 14 November 2008 , pp. e133-e133(1)

Publisher: Oxford University Press

Invertebrate and fungal model organisms: emerging platforms for drug discovery

Authors: Stilwell, Geoff E; Westlund, Bethany

Source: Expert Opinion on Drug Discovery, Volume 3, Number 12, December 2008 , pp. 1383-1395(13)

Publisher: Informa Healthcare

Strategies for automated analysis of C. elegans locomotion

Authors: Buckingham, Steven; Sattelle, David

Source: Invertebrate Neuroscience, Volume 8, Number 3, September 2008 , pp. 121-131(11)

Publisher: Springer

Chemogenomics and Parasitology: Small Molecules and Cell-Based Assays to Study Infectious Processes

Authors: Muskavitch, Marc A.T.; Barteneva, Natasha; Gubbels, Marc-Jan

Source: Combinatorial Chemistry & High Throughput Screening, Volume 11, Number 8, September 2008 , pp. 624-646(23)

Publisher: Bentham Science Publishers

Baker's yeast as a tool for the development of antifungal drugs which target cell integrity - an update

Author: Heinisch, Jürgen J

Source: Expert Opinion on Drug Discovery, Volume 3, Number 8, August 2008 , pp. 931-943(13)

Publisher: Informa Healthcare

Post-translational Modifications of Recombinant Proteins: Significance for Biopharmaceuticals

Authors: Jenkins, Nigel; Murphy, Lisa; Tyther, Ray

Source: Molecular Biotechnology, Volume 39, Number 2, June 2008 , pp. 113-118(6)

Publisher: Humana Press

The use of voltage-sensitive dyes to monitor signal-induced changes in membrane potential-ABA triggered membrane depolarization in guard cells

Authors: Konrad, Kai R.; Hedrich, Rainer

Source: The Plant Journal, Volume 55, Number 1, July 2008 , pp. 161-173(13)

Publisher: Blackwell Publishing

Hunting for predictive computational drug-discovery models

Author: Snow, Christopher D

Source: Expert Review of Anti-Infective Therapy, Volume 6, Number 3, June 2008 , pp. 291-293(3)

Publisher: Expert Reviews

The challenge of selecting protein kinase assays for lead discovery optimization

Authors: Ma, Haiching; Deacon, Sean; Horiuchi, Kurumi

Source: Expert Opinion on Drug Discovery, Volume 3, Number 6, June 2008 , pp. 607-621(15)

Publisher: Informa Healthcare

Cell-based assays to identify inhibitors of viral disease

Authors: Green, Neil; D Ott, Robert; J Isaacs, Richard; Fang, Hong

Source: Expert Opinion on Drug Discovery, Volume 3, Number 6, June 2008 , pp. 671-676(6)

Publisher: Informa Healthcare

Editorial [Hot Topic: GPCR High Throughput Screening (Part 1) (Guest Editors: David P. Siderovski and Francis S. Willard)]

Authors: Willard, Francis S.; Siderovski, David P.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 11, Number 5, June 2008 , pp. 336-336(1)

Publisher: Bentham Science Publishers