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Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies

Author: Del Prato, S.

Source: Diabetic Medicine, Volume 26, Number 12, December 2009 , pp. 1185-1192(8)

Publisher: Blackwell Publishing

Obesity treatment: novel peripheral targets

Authors: Field, Benjamin C. T.; Chaudhri, Owais B.; Bloom, Stephen R.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 830-843(14)

Publisher: Blackwell Publishing

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers

Authors: Lim, Kyoung Soo; Cho, Joo-Youn; Kim, Bo-Hyung; Kim, Jung-Ryul; Kim, Hwa-Sook; Kim, Dong-Kyu; Kim, Sung-Ho; Yim, Hyeon Joo; Lee, Sung-Hack; Shin, Sang-Goo; Jang, In-Jin; Yu, Kyung-Sang

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 883-890(8)

Publisher: Blackwell Publishing

Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide

Authors: Jacobsen, Lisbeth V.; Hindsberger, Charlotte; Robson, Richard; Zdravkovic, Milan

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 898-905(8)

Publisher: Blackwell Publishing

Glucagon receptor mediates calcium signaling by coupling to Gα_q/11 and Gα_i/o in HEK293 cells

Authors: Xu, Yazhen; Xie, Xin

Source: Journal of Receptors and Signal Transduction, Volume 29, Number 6, December 2009 , pp. 318-325(8)

Publisher: Informa Healthcare

Is liraglutide or exenatide better in type 2 diabetes?

Author: Doggrell, Sheila A

Source: Expert Opinion on Pharmacotherapy, Volume 10, Number 16, November 2009 , pp. 2769-2772(4)

Publisher: Informa Healthcare

Diabetic Medications in Pregnancy

Authors: Young, James; Anwar, Aresh

Source: Current Diabetes Reviews, Volume 5, Number 4, November 2009 , pp. 252-258(7)

Publisher: Bentham Science Publishers

Treatment of Type 1 Diabetic Patients with Glucagon-Like Peptide-1 (GLP-1) and GLP-1R Agonists

Authors: Kielgast, Urd; Holst, Jens J.; Madsbad, Sten

Source: Current Diabetes Reviews, Volume 5, Number 4, November 2009 , pp. 266-275(10)

Publisher: Bentham Science Publishers

Incretin-based therapies: Therapeutic rationale and pharmacological promise for type 2 diabetes

Authors: Wick, Allison; Newlin, Kelley

Source: Journal of the American Academy of Nurse Practitioners, Volume 21, Supplement 1, November 2009 , pp. 623-630(8)

Publisher: Blackwell Publishing

New developments in incretin-based therapies: The current state of the field

Author: Robertson, Carolyn

Source: Journal of the American Academy of Nurse Practitioners, Volume 21, Supplement 1, November 2009 , pp. 631-641(11)

Publisher: Blackwell Publishing

Optimizing outcomes with incretin-based therapies: Practical information for nurse practitioners to share with patients

Author: Fleury-Milfort, Evelyne

Source: Journal of the American Academy of Nurse Practitioners, Volume 21, Supplement 1, November 2009 , pp. 642-650(9)

Publisher: Blackwell Publishing

Pharmacokinetic and pharmacodynamic properties of taspoglutide, a once-weekly, human GLP-1 analogue, after single-dose administration in patients with Type 2 diabetes

Authors: Kapitza, C.; Heise, T.; Birman, P.; Jallet, K.; Ramis, J.; Balena, R.

Source: Diabetic Medicine, Volume 26, Number 11, November 2009 , pp. 1156-1164(9)

Publisher: Blackwell Publishing

Amyloidogenicity and Aggregate Cytotoxicity of Human Glucagon-Like Peptide-1 (hGLP-1)

Authors: Poon, S.; Birkett, N. R.; Fowler, S. B.; Luisi, B. F.; Dobson, C. M.; Zurdo, J.

Source: Protein and Peptide Letters, Volume 16, Number 12, December 2009 , pp. 1548-1556(9)

Publisher: Bentham Science Publishers

Clinical pharmacology of alogliptin, a dipeptidyl peptidase-4 inhibitor, for the treatment of Type 2 diabetes

Authors: Christopher, Ronald; Karim, Aziz

Source: Expert Review of Clinical Pharmacology, Volume 2, Number 6, November 2009 , pp. 589-600(12)

Publisher: Expert Reviews

Combination of nateglinide with thiazolidinediones in Type 2 diabetes

Authors: Voulgari, Christina; Tentolouris, Nicholas

Source: Expert Review of Endocrinology and Metabolism, Volume 4, Number 6, November 2009 , pp. 537-552(16)

Publisher: Expert Reviews

Exenatide compared with long-acting insulin to achieve glycaemic control with minimal weight gain in patients with type 2 diabetes: results of the Helping Evaluate Exenatide in patients with diabetes compared with Long-Acting insulin (HEELA) study

Authors: Davies, M. J.; Donnelly, R.; Barnett, A. H.; Jones, S.; Nicolay, C.; Kilcoyne, A.

Source: Diabetes, Obesity and Metabolism, Volume 11, Number 12, December 2009 , pp. 1153-1162(10)

Publisher: Blackwell Publishing

Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue

Authors: Jendle, J.; Nauck, M. A.; Matthews, D. R.; Frid, A.; Hermansen, K.; Düring, M.; Zdravkovic, M.; Strauss, B. J.; Garber, A. J.

Source: Diabetes, Obesity and Metabolism, Volume 11, Number 12, December 2009 , pp. 1163-1172(10)

Publisher: Blackwell Publishing

Intestinal motor activity, endoluminal motion and transit

Authors: de iorio, f.; malagelada, c.; azpiroz, f.; maluenda, m.; violanti, c.; igual, l.; vitrià, j.; malagelada, j.-r.

Source: Neurogastroenterology and Motility, Volume 21, Number 12, December 2009 , pp. 1264-e119(-1263)

Publisher: Blackwell Publishing

Novel selective ligands for free fatty acid receptors GPR120 and GPR40

Authors: Hara, Takafumi; Hirasawa, Akira; Sun, Qi; Sadakane, Keiko; Itsubo, Chisato; Iga, Tomoyo; Adachi, Tetsuya; Koshimizu, Taka-aki; Hashimoto, Toshihiro; Asakawa, Yoshinori; Tsujimoto, Gozoh

Source: Naunyn-Schmiedeberg's Archives of Pharmacology, Volume 380, Number 3, September 2009 , pp. 247-255(9)

Publisher: Springer

Hormonal regulation of CYP1A expression

Authors: Monostory, Katalin; Pascussi, Jean-Marc; Kóbori, László; Dvorak, Zdenek

Source: Drug Metabolism Reviews, Volume 41, Number 4, November 2009 , pp. 547-572(26)

Publisher: Informa Healthcare