Search Results

Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy

Authors: Lutz, Stefan; Liu, Lingfeng; Liu, Yichen

Source: CHIMIA International Journal for Chemistry, Volume 63, Number 11, November 2009 , pp. 737-744(8)

Publisher: Swiss Chemical Society

Small Agarose Microcapsules With Cell-Enclosing Hollow Core for Cell Therapy: Transplantation of Ifosfamide-Activating Cells to the Mice With Preestablished Subcutaneous Tumor

Authors: Sakai, Shinji; Hashimoto, Ichiro; Tanaka, Shinji; Salmons, Brian; Kawakami, Koei

Source: Cell Transplantation, Volume 18, Number 8, 2009 , pp. 933-939(7)

Publisher: Cognizant Communication Corporation

HuR modulates gemcitabine efficacy: new perspectives in pancreatic cancer treatment

Authors: Maréchal, Raphaël; Van Laethem, Jean-Luc

Source: Expert Review of Anticancer Therapy, Volume 9, Number 10, October 2009 , pp. 1439-1441(3)

Publisher: Expert Reviews

Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model

Authors: You, Mi-Hyeon; Kim, Wang-Joon; Shim, Wooyoung; Lee, Sang-Rim; Lee, Gwang; Choi, Sangdun; Kim, Dae-Yong; Kim, Yong Man; Kim, Hyunsoo; Han, Sang-Uk

Source: Journal of Gastroenterology and Hepatology, Volume 24, Number 8, August 2009 , pp. 1393-1400(8)

Publisher: Blackwell Publishing

Antibody-Directed Enzyme Prodrug Therapy: A Promising Approach for a Selective Treatment of Cancer Based on Prodrugs and Monoclonal Antibodies

Authors: Tietze, Lutz F.; Krewer, Birgit

Source: Chemical Biology & Drug Design, Volume 74, Number 3, September 2009 , pp. 205-211(7)

Publisher: Blackwell Publishing

Optimization ofd-amino acid oxidase for low substrate concentrations - towards a cancer enzyme therapy

Authors: Rosini, Elena; Pollegioni, Loredano; Ghisla, Sandro; Orru, Roberto; Molla, Gianluca

Source: FEBS Journal, Volume 276, Number 17, September 2009 , pp. 4921-4932(12)

Publisher: Blackwell Publishing

Novel application of lentiviral vectors towards treatment of graft-versus-host disease

Authors: Scaife, Matthew D; Neschadim, Anton; Fowler, DH; Medin, JA

Source: Expert Opinion on Biological Therapy, Volume 9, Number 6, June 2009 , pp. 749-761(13)

Publisher: Informa Healthcare

Novel Analogues of CC-1065 and the Duocarmycins for the Use in Targeted Tumour Therapies

Authors: Tietze, Lutz F.; Krewer, Birgit

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 9, Number 3, March 2009 , pp. 304-325(22)

Publisher: Bentham Science Publishers

Targeted Tumor Therapies at a Glance

Authors: Fuchs, H.; Bachran, C.

Source: Current Drug Targets, Volume 10, Number 2, February 2009 , pp. 89-93(5)

Publisher: Bentham Science Publishers

Targeting: The ADEPT Story So Far

Author: Bagshawe, K. D.

Source: Current Drug Targets, Volume 10, Number 2, February 2009 , pp. 152-157(6)

Publisher: Bentham Science Publishers

Gene therapy approaches to enhance bioreductive drug treatment

Authors: Cowen, R L; Garside, E J; Fitzpatrick, B; Papadopoulou, M V; Williams, K J

Source: British Journal of Radiology, Volume 81, Supplement 1, October 2008 , pp. S45-S56(1)

Publisher: British Institute of Radiology

Expression and characterization of the biofilm-related and carnosine-hydrolyzing aminoacylhistidine dipeptidase from Vibrio alginolyticus

Authors: Wang, Ting-Yi; Chen, Yi-Chin; Kao, Liang-Wei; Chang, Chin-Yuan; Wang, Yu-Kuo; Liu, Yen-Hsi; Feng, Jen-Min; Wu, Tung-Kung

Source: FEBS Journal, Volume 275, Number 20, October 2008 , pp. 5007-5020(14)

Publisher: Blackwell Publishing

Cytochrome P450-Activated Prodrugs: Targeted Drug Delivery

Authors: Huttunen, Kristiina M.; Mahonen, Niina; Raunio, Hannu; Rautio, Jarkko

Source: Current Medicinal Chemistry, Volume 15, Number 23, October 2008 , pp. 2346-2365(20)

Publisher: Bentham Science Publishers

Modifications of human carboxylesterase for improved prodrug activation

Authors: Hatfield, Jason M; Wierdl, Monika; Wadkins, Randy M; Potter, Philip M

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 4, Number 9, September 2008 , pp. 1153-1165(13)

Publisher: Informa Healthcare

Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein

Authors: Xing, Ligang; Deng, Xuelong; Kotedia, Khushali; Ackerstaff, Ellen; Ponomarev, Vladimir; Clifton Ling, C.; Koutcher, Jason; Li, Gloria

Source: Acta Oncologica, Volume 47, Number 7, 2008 , pp. 1211-1220(10)

Publisher: Informa Healthcare

Catalytic Activity of Certain Antibodies as a Potential Tool for Drug Synthesis and for Directed Prodrug Therapies

Authors: Wojcik, T.; Kiec-Kononowicz, K.

Source: Current Medicinal Chemistry, Volume 15, Number 16, July 2008 , pp. 1606-1615(10)

Publisher: Bentham Science Publishers

Candidate mechanisms for capecitabine-related hand-foot syndrome

Authors: Milano, Gérard; Etienne-Grimaldi, Marie-Christine; Mari, Mireille; Lassalle, Sandra; Formento, Jean-Louis; Francoual, Mireille; Lacour, Jean-Philippe; Hofman, Paul

Source: British Journal of Clinical Pharmacology, Volume 66, Number 1, July 2008 , pp. 88-95(8)

Publisher: Blackwell Publishing

Suicide gene/prodrug therapy using salmonella-mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6-methoxypurine 2^′-deoxyriboside in murine mammary carcinoma 4T1 model

Authors: Fu, Wei; Lan, Hekui; Liang, Shenghua; Gao, Tong; Ren, Daming

Source: Cancer Science, Volume 99, Number 6, June 2008 , pp. 1172-1179(8)

Publisher: Blackwell Publishing

Novel Beta-Lactam Antibiotics Derivatives: Their New Applications as Gene Reporters, Antitumor Prodrugs and Enzyme Inhibitors

Authors: Xing, Bengang; Rao, Jianghong; Liu, Rongrong

Source: Mini Reviews in Medicinal Chemistry, Volume 8, Number 5, May 2008 , pp. 455-471(17)

Publisher: Bentham Science Publishers

Targeted suicide gene therapy for small cell lung cancer

Authors: Pedersen, Nina; Poulsen, Hans Skovgaard; Christensen, Camilla Laulund

Source: Apmis, Volume 116, Number 5, May 2008 , pp. 412-413(2)

Publisher: Blackwell Publishing