Search Results

Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions

Authors: Sharma, P.; Holmes, V. E.; Elsby, R.; Lambert, C.; Surry, D.

Source: Xenobiotica, Volume 40, Number 1, January 2010 , pp. 24-37(14)

Publisher: Informa Healthcare

The α₂ adrenoceptor antagonist idazoxan alleviatesl-DOPA-induced dyskinesia by reduction of striatal dopamine levels: an in vivo microdialysis study in 6-hydroxydopamine-lesioned rats

Authors: Buck, Kerstin; Voehringer, Patrizia; Ferger, Boris

Source: Journal of Neurochemistry, Volume 112, Number 2, January 2010 , pp. 444-452(9)

Publisher: Blackwell Publishing

A computerized system for detecting signals due to drug-drug interactions in spontaneous reporting systems

Authors: Qian, Yifeng; Ye, Xiaofei; Du, Wenmin; Ren, Jingtian; Sun, Yalin; Wang, Hainan; Luo, Baozhang; Gao, Qingbin; Wu, Meijing; He, Jia

Source: British Journal of Clinical Pharmacology, Volume 69, Number 1, January 2010 , pp. 67-73(7)

Publisher: Blackwell Publishing

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

Authors: Greenblatt, David J.; Peters, Diane E.; Oleson, Lauren E.; Harmatz, Jerold S.; MacNab, Malcolm W.; Berkowitz, Noah; Zinny, Miguel A.; Court, Michael H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 920-927(8)

Publisher: Blackwell Publishing

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A

Authors: Turpault, Sandrine; Brian, William; Van Horn, Robert; Santoni, Alix; Poitiers, Franck; Donazzolo, Yves; Boulenc, Xavier

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 928-935(8)

Publisher: Blackwell Publishing

Role of microRNAs in the regulation of drug metabolism and disposition

Author: Yu, Ai-Ming

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 12, December 2009 , pp. 1513-1528(16)

Publisher: Informa Healthcare

Effects of rifampicin on the pharmacokinetics of roflumilast and roflumilast N-oxide in healthy subjects

Authors: Nassr, Nassr; Huennemeyer, Andreas; Herzog, Rolf; von Richter, Oliver; Hermann, Robert; Koch, Manuela; Duffy, Kevin; Zech, Karl; Lahu, Gezim

Source: British Journal of Clinical Pharmacology, Volume 68, Number 4, October 2009 , pp. 580-587(8)

Publisher: Blackwell Publishing

In vitro model for the prediction of clinical CYP3A4 induction using HepaRG cells

Authors: Kaneko, A.; Kato, M.; Sekiguchi, N.; Mitsui, T.; Takeda, K.; Aso, Y.

Source: Xenobiotica, Volume 39, Number 11, November 2009 , pp. 803-810(8)

Publisher: Informa Healthcare

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel

Authors: Nishiya, Y.; Hagihara, K.; Kurihara, A.; Okudaira, N.; Farid, N.A.; Okazaki, O.; Ikeda, T.

Source: Xenobiotica, Volume 39, Number 11, November 2009 , pp. 836-843(8)

Publisher: Informa Healthcare

Interaction of beta-blockers with the renal uptake transporter OCT2

Authors: Bachmakov, I.; Glaeser, H.; Endress, B.; Mörl, F.; König, J.; Fromm, M. F.

Source: Diabetes, Obesity and Metabolism, Volume 11, Number 11, November 2009 , pp. 1080-1083(4)

Publisher: Blackwell Publishing

Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis

Authors: Ung, D.; Parkman, H. P.; Nagar, S.

Source: Xenobiotica, Volume 39, Number 10, October 2009 , pp. 749-756(8)

Publisher: Informa Healthcare

Effect of a proton pump inhibitor on the pharmacokinetics of imatinib

Authors: Egorin, Merrill J.; Shah, Dhvani D.; Christner, Susan M.; Yerk, Mara A.; Komazec, Kristin A.; Appleman, Leonard R.; Redner, Robert L.; Miller, Brian M.; Beumer, Jan H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 3, September 2009 , pp. 370-374(5)

Publisher: Blackwell Publishing

Influence of transdermal rotigotine on ovulation suppression by a combined oral contraceptive

Authors: Braun, Marina; Elshoff, Jan-Peer; Andreas, Jens-Otto; Müller, Louise Ischen; Horstmann, Rolf

Source: British Journal of Clinical Pharmacology, Volume 68, Number 3, September 2009 , pp. 386-394(9)

Publisher: Blackwell Publishing

Onychomycosis and diabetes

Authors: Cathcart, S; Cantrell, W; Elewski, BE

Source: Journal of the European Academy of Dermatology & Venereology, Volume 23, Number 10, October 2009 , pp. 1119-1122(4)

Publisher: Blackwell Publishing

Gefitinib-phenytoin interaction is not correlated with the ¹⁴C-erythromycin breath test in healthy male volunteers

Authors: Chhun, Stephanie; Verstuyft, Celine; Rizzo-Padoin, Nathalie; Simoneau, Guy; Becquemont, Laurent; Peretti, Ilana; Swaisland, Alan; Wortelboer, Robert; Bergmann, Jean Francois; Mouly, Stephane

Source: British Journal of Clinical Pharmacology, Volume 68, Number 2, August 2009 , pp. 226-237(12)

Publisher: Blackwell Publishing

Natural polyphenols antagonize the antimyeloma activity of proteasome inhibitor bortezomib by direct chemical interaction

Authors: Kim, Tae Young; Park, Jongmin; Oh, Bora; Min, Hyun Jung; Jeong, Tae-Sook; Lee, Jae Hoon; Suh, Cheolwon; Cheong, June-Won; Kim, Hyo Jung; Yoon, Sung-Soo; Park, Seung Bum; Lee, Dong Soon

Source: British Journal of Haematology, Volume 146, Number 3, August 2009 , pp. 270-281(12)

Publisher: Blackwell Publishing

Pharmacokinetic interaction between nevirapine and darunavir with low-dose ritonavir in HIV-1-infected patients

Authors: Sekar, Vanitha; Lefebvre, Eric; Mariën, Kris; De Pauw, Martine; Vangeneugden, Tony; Pozniak, Anton; Hoetelmans, Richard M. W.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 1, July 2009 , pp. 116-119(4)

Publisher: Blackwell Publishing

Safety and Efficacy of Raltegravir in HIV-Infected Transplant Patients Cotreated with Immunosuppressive Drugs

Authors: Tricot, L.; Teicher, E.; Peytavin, G.; Zucman, D.; Conti, F.; Calmus, Y.; Barrou, B.; Duvivier, C.; Fontaine, C.; Welker, Y.; Billy, C.; de Truchis, P.; Delahousse, M.; Vittecoq, D.; Salmon-Céron, D.

Source: American Journal of Transplantation, Volume 9, Number 8, August 2009 , pp. 1946-1952(7)

Publisher: Blackwell Publishing

Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein

Authors: Tachibana, T.; Kato, M.; Watanabe, T.; Mitsui, T.; Sugiyama, Y.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 430-443(14)

Publisher: Informa Healthcare

Nuclear receptors: the controlling force in drug metabolism of the liver?

Authors: Plant, N.; Aouabdi, S.

Source: Xenobiotica, Volume 39, Number 8, August 2009 , pp. 597-605(9)

Publisher: Informa Healthcare