Search Results

Streamlining hit discovery and optimization with a yoctoliter scale DNA reactor

Authors: Heitner, Tara Renee; Hansen, Nils Jakob Vest

Source: Expert Opinion on Drug Discovery, Volume 4, Number 11, November 2009 , pp. 1201-1213(13)

Publisher: Informa Healthcare

Chemogenomic Strategies to Expand the Bioactive Chemical Space

Authors: Jacoby, E.; Mozzarelli, A.

Source: Current Medicinal Chemistry, Volume 16, Number 33, November 2009 , pp. 4374-4381(8)

Publisher: Bentham Science Publishers

Conformational Sampling and Energetics of Drug-Like Molecules

Authors: Foloppe, Nicolas; Chen, I-Jen

Source: Current Medicinal Chemistry, Volume 16, Number 26, September 2009 , pp. 3381-3413(33)

Publisher: Bentham Science Publishers

Combinatorial Chemistry on Solid Support in the Search for Central Nervous System Agents

Authors: Zajdel, Pawel; Pawlowski, Maciej; Martinez, Jean; Subra, Gilles

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 7, August 2009 , pp. 723-739(17)

Publisher: Bentham Science Publishers

Fragment-based identification of druggable `hot spots' of proteins using Fourier domain correlation techniques

Authors: Brenke, Ryan; Kozakov, Dima; Chuang, Gwo-Yu; Beglov, Dmitri; Hall, David; Landon, Melissa R.; Mattos, Carla; Vajda, Sandor

Source: Bioinformatics, Volume 25, Number 5, 1 March 2009 , pp. 621-627(7)

Publisher: Oxford University Press

In Silico Prediction of Drug Properties

Author: Hutter, M. C.

Source: Current Medicinal Chemistry, Volume 16, Number 2, January 2009 , pp. 189-202(14)

Publisher: Bentham Science Publishers

Sodium Channel Inhibitor Drug Discovery Using Automated High Throughput Electrophysiology Platforms

Authors: Castle, Neil; Printzenhoff, David; Zellmer, Shannon; Antonio, Brett; Wickenden, Alan; Silvia, Christopher

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 1, January 2009 , pp. 107-122(16)

Publisher: Bentham Science Publishers

Editorial [Hot Topic: Quantitative studies on Structure-Activity and Structure-Property Relationships (QSAR/QSPR) (Guest Editor: Humberto Gonzalez-Diaz)]

Author: Gonzalez-Diaz, Humberto

Source: Current Topics in Medicinal Chemistry, Volume 8, Number 18, December 2008 , pp. 1554-1554(1)

Publisher: Bentham Science Publishers

Editorial [Hot Topic: Virtual Screening (Guest Editor: Bruno O. Villoutreix) ]

Author: Villoutreix, Bruno O.

Source: Current Computer - Aided Drug Design, Volume 4, Number 3, September 2008 , pp. 154-155(2)

Publisher: Bentham Science Publishers

Collections of Compounds - How to Deal with them?

Authors: Dubois, Julie; Bourg, Stephane; Vrain, Christel; Morin-Allory, Luc

Source: Current Computer - Aided Drug Design, Volume 4, Number 3, September 2008 , pp. 156-168(13)

Publisher: Bentham Science Publishers

Fragment-Based Approach to Drug Lead Discovery: Overview and Advances in Various Techniques

Authors: Fattori, Daniela; Squarcia, Antonella; Bartoli, Sandra

Source: Drugs in R&D, Volume 9, Number 4, 2008 , pp. 217-227(11)

Publisher: Adis International

How to Efficiently Include Receptor Flexibility During Computational Docking

Authors: May, Andreas; Sieker, Florian; Zacharias, Martin

Source: Current Computer - Aided Drug Design, Volume 4, Number 2, June 2008 , pp. 143-153(11)

Publisher: Bentham Science Publishers

Editorial [Hot Topic: Tyrosine Kinase Inhibitors in Cancer Therapy (Guest Editor: S. Eckhardt)]

Author: Eckhardt, S.

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 5, June 2008 , pp. 461-461(1)

Publisher: Bentham Science Publishers

Alkylsquarates as Key Intermediates for the Rapid Preparation of Original Drug-Inspired Compounds

Authors: Charton, Julie; Charruault, Lise; Deprez-Poulain, Rebecca; Deprez, Benoit

Source: Combinatorial Chemistry & High Throughput Screening, Volume 11, Number 4, May 2008 , pp. 294-303(10)

Publisher: Bentham Science Publishers

Editorial from Guest Editors [ High Throughput Screening Using Eukaryotic Platform Organisms Guest Editors: Hildegard Buning and Christian J. Buchholz ]

Authors: Buning, Hildegard; Buchholz, Christian J.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 11, Number 2, February 2008 , pp. 84-85(2)

Publisher: Bentham Science Publishers

Evaluation of the utility of homology models in high throughput docking

Authors: Ferrara, Philippe; Jacoby, Edgar

Source: Journal of Molecular Modeling, Volume 13, Number 8, August 2007 , pp. 897-905(9)

Publisher: Springer

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZeneca's Drug Discovery Programmes

Authors: Albert, Jeffrey S.; Blomberg, Niklas; Breeze, Alexander L.; Brown, Alastair J.H.; Burrows, Jeremy N.; Edwards, Philip D.; Folmer, Rutger H.A.; Geschwindner, Stefan; Griffen, Ed J.; Kenny, Peter W.; Nowak, Thorsten; Olsson, Lise-Lotte; Sanganee, Hitesh; Shapiro, Adam B.

Source: Current Topics in Medicinal Chemistry, Volume 7, Number 16, August 2007 , pp. 1600-1629(30)

Publisher: Bentham Science Publishers

Lending a helping hand, screening chemical libraries for compounds that enhance β-hexosaminidase A activity in GM2 gangliosidosis cells

Authors: Tropak, Michael B.; Mahuran, Don

Source: FEBS Journal, Volume 274, Number 19, October 2007 , pp. 4951-4961(11)

Publisher: Blackwell Publishing

High-throughput flow cytometry for drug discovery

Authors: Edwards, Bruce S; Young, Susan M; Saunders, Matthew J; Bologa, Cristian; Oprea, Tudor I; Ye, Richard D; Prossnitz, Eric R; Graves, Steven W; Sklar, Larry A

Source: Expert Opinion on Drug Discovery, Volume 2, Number 5, May 2007 , pp. 685-696(12)

Publisher: Informa Healthcare

Fragment-Based Approaches to Lead Discovery

Authors: Wyss, Daniel F.; Eaton, Hugh L.

Source: Frontiers in Drug Design & Discovery: Structure-Based Drug Design in the 21st Century, Volume 3, Number 1, 1 March 2007 , pp. 171-202(32)

Publisher: Bentham Science Publishers