Search Results

QT Interval Prolongation: Preclinical and Clinical Testing Arrhythmogenesis in Drugs and Regulatory Implications

Authors: Giorgi, Mariano A.; Bolanos, Ricardo; Gonzalez, Claudio D.; Di Girolamo, Guillermo

Source: Current Drug Safety, Volume 5, Number 1, January 2010 , pp. 54-57(4)

Publisher: Bentham Science Publishers

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Authors: Goble, Jessica L.; Adendorff, Matthew R.; de Beer, Tjaart A.P.; Stephens, Linda L.; Blatch, Gregory L.

Source: Protein and Peptide Letters, Volume 17, Number 1, January 2010 , pp. 109-120(12)

Publisher: Bentham Science Publishers

Mechanisms of Allostery and Membrane Attachment in Ras GTPases: Implications for Anti-Cancer Drug Discovery

Author: Gorfe, A. A.

Source: Current Medicinal Chemistry, Volume 17, Number 1, January 2010 , pp. 1-9(9)

Publisher: Bentham Science Publishers

Molecular Recognition and Drug-Lead Identification: What Can Molecular Simulations Tell Us?

Authors: Morra, G.; Genoni, A.; Neves, M. A.C.; Merz Jr., K. M.; Colombo, G.

Source: Current Medicinal Chemistry, Volume 17, Number 1, January 2010 , pp. 25-41(17)

Publisher: Bentham Science Publishers

Design and Development of Nanovehicle-Based Delivery Systems for Preventive or Therapeutic Supplementation with Flavonoids

Authors: Leonarduzzi, G.; Testa, G.; Sottero, B.; Gamba, P.; Poli, G.

Source: Current Medicinal Chemistry, Volume 17, Number 1, January 2010 , pp. 74-95(22)

Publisher: Bentham Science Publishers

A Pursuit of Smart Chemistry Tackling Complex Biology by Way of Inventive Drug Design

Author: Sawyer, Tomi K.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 1-2(2)

Publisher: Blackwell Publishing

Structure-based Drug Metabolism Predictions for Drug Design

Authors: Sun, Hao; Scott, Dennis O.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 3-17(15)

Publisher: Blackwell Publishing

Structural Analysis of DFG-in and DFG-out Dual Src-Abl Inhibitors Sharing a Common Vinyl Purine Template

Authors: Zhou, Tianjun; Commodore, Lois; Huang, Wei-Sheng; Wang, Yihan; Sawyer, Tomi K.; Shakespeare, William C.; Clackson, Tim; Zhu, Xiaotian; Dalgarno, David C.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 18-28(11)

Publisher: Blackwell Publishing

Shape- and Chemical Feature-Based 3D-Pharmacophore Model Generation and Virtual Screening: Identification of Potential Leads for P. falciparum DHFR Enzyme Inhibition

Authors: Adane, Legesse; Patel, Dhilon. S.; Bharatam, Prasad V.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 115-126(12)

Publisher: Blackwell Publishing

Thorough QT Studies: Questions and Quandaries

Authors: Malik, Marek; Garnett, Christine E.; Zhang, Joanne

Source: Drug Safety, Volume 33, Number 1, 1 January 2010 , pp. 1-14(14)

Publisher: Adis International

Association between Drug and Vaccine Use and Acute Immune Thrombocytopenia in Childhood: A Case-Control Study in Italy

Authors: Bertuola, Federica; Morando, Carla; Menniti-Ippolito, Francesca; >Roberto Da Cas,; Capuano, Annalisa; Perilongo, Giorgio; >Liviana Da Dalt,

Source: Drug Safety, Volume 33, Number 1, 1 January 2010 , pp. 65-72(8)

Publisher: Adis International

Drug-resistant tuberculosis in six hospitals in Rio de Janeiro, Brazil

Authors: Brito, R.C.; Mello, F.C.Q.; Andrade, M.K.; Oliveira, H.; Costa, W.; Matos, H.J.; Lourenço, M.C.; Rolla, V.C.; Fonseca, L.; Ruffino Netto, A.; Kritski, A.L.

Source: The International Journal of Tuberculosis and Lung Disease, Volume 14, Number 1, January 2010 , pp. 24-33(10)

Publisher: International Union Against Tuberculosis and Lung Disease

Homology modelling and identification of active site residue in the nucleoprotein of influenza virus through in silico strategy for drug target

Authors: Somvanshi, Pallavi; Singh, Vijai

Source: International Journal of Medical Engineering and Informatics, Volume 2, Number 1, 2 December 2009 , pp. 26-36(11)

Publisher: Inderscience Publishers

Alcohol, Tobacco, and Nonmedical Drug Use in Older U.S. Adults: Data from the 2001/02 National Epidemiologic Survey of Alcohol and Related Conditions

Authors: Moore, Alison A.; Karno, Mitchell P.; Grella, Christine E.; Lin, James C.; Warda, Umme; Liao, Diana H.; Hu, Peifeng

Source: Journal of the American Geriatrics Society, Volume 57, Number 12, December 2009 , pp. 2275-2281(7)

Publisher: Blackwell Publishing

Long-Term Effects of Minimum Drinking Age Laws on Past-Year Alcohol and Drug Use Disorders

Authors: Norberg, Karen E.; Bierut, Laura J.; Grucza, Richard A.

Source: Alcoholism Clinical and Experimental Research, Volume 33, Number 12, December 2009 , pp. 2180-2190(11)

Publisher: Blackwell Publishing

Multisubstrate adduct inhibitors: Drug design and biological tools

Authors: Le Calvez, P. B.; Scott, C. J.; Migaud, M.E.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 6, December 2009 , pp. 1291-1318(28)

Publisher: Informa Healthcare

Design of a 24-hour controlled porosity osmotic pump system containing PVP: formulation variables

Authors: Yakubu, Rabiu; Peh, Kok K.; Tan, Yvonne T.F.

Source: Drug Development and Industrial Pharmacy, Volume 35, Number 12, December 2009 , pp. 1430-1438(9)

Publisher: Informa Healthcare

Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology

Authors: Shah, Syed Nisar Hussain; Asghar, Sajid; Choudhry, Muhammad Akram; Akash, Muhammad Sajid Hamid; Rehman, Nisar ur; Baksh, Sattar

Source: Drug Development and Industrial Pharmacy, Volume 35, Number 12, December 2009 , pp. 1470-1478(9)

Publisher: Informa Healthcare

Formulation design and pharmaceutical development of a novel controlled release form of azithromycin for single-dose therapy

Authors: Lo, Julian B.; Appel, Leah E.; Herbig, Scott M.; McCray, Scott B.; Thombre, Avinash G.

Source: Drug Development and Industrial Pharmacy, Volume 35, Number 12, December 2009 , pp. 1522-1529(8)

Publisher: Informa Healthcare

Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-α

Authors: Onnis, Valeria; Kinsella, Gemma K; Carta, Giorgio; Fayne, Darren; Lloyd, David G

Source: Future Medicinal Chemistry, Volume 1, Number 3, June 2009 , pp. 483-499(17)

Publisher: Future Science