Search Results

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers

Authors: Lim, Kyoung Soo; Cho, Joo-Youn; Kim, Bo-Hyung; Kim, Jung-Ryul; Kim, Hwa-Sook; Kim, Dong-Kyu; Kim, Sung-Ho; Yim, Hyeon Joo; Lee, Sung-Hack; Shin, Sang-Goo; Jang, In-Jin; Yu, Kyung-Sang

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 883-890(8)

Publisher: Blackwell Publishing

Efficacy and limitation of bone marrow transplantation in the treatment of acute and subacute liver failure in rats

Authors: Tokai, Hirotaka; Kawashita, Yujo; Ito, Yuichiro; Yamanouchi, Kosho; Takatsuki, Mitsuhisa; Eguchi, Susumu; Tajima, Yoshitsugu; Kanematsu, Takashi

Source: Hepatology Research, Volume 39, Number 11, November 2009 , pp. 1137-1143(7)

Publisher: Blackwell Publishing

The backbone of oral glucose-lowering therapy: time for a paradigm shift?

Author: Seufert, Jochen

Source: Fundamental & Clinical Pharmacology, Volume 23, Number 6, December 2009 , pp. 651-667(17)

Publisher: Blackwell Publishing

Epitope analysis of the rat dipeptidyl peptidase IV monoclonal antibody 6A3 that blocks pericellular fibronectin-mediated cancer cell adhesion

Authors: Hung, Ting-Ting; Wu, Jun-Yi; Liu, Ju-Fang; Cheng, Hung-Chi

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6548-6559(12)

Publisher: Blackwell Publishing

Sitagliptin 100 mg daily effect on DPP-4 inhibition and compound-specific glycemic improvement

Authors: Alba, M.; Sheng, D.; Guan, Y.; Williams-Herman, D.; Larson, P.; Sachs, J.R.; Thornberry, N.; Herman, G.; Kaufman, K.D.; Goldstein, B.J.

Source: Current Medical Research and Opinion, Volume 25, Number 10, October 2009 , pp. 2507-2514(8)

Publisher: Informa Healthcare

Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine

Authors: Al-masri, Ihab M.; Mohammad, Mohammad K.; Tahaa, Mutasem O.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 5, October 2009 , pp. 1061-1066(6)

Publisher: Informa Healthcare

Roles of cAMP signalling in insulin granule exocytosis

Authors: Seino, S.; Takahashi, H.; Fujimoto, W.; Shibasaki, T.

Source: Diabetes, Obesity and Metabolism, Volume 11, Supplement 4, November 2009 , pp. 180-188(9)

Publisher: Blackwell Publishing

Effect of sodium, potassium, calcium and magnesium chloride salts on porcine muscle proteases

Authors: Armenteros, Mónica; Aristoy, M-Concepción; Toldrá, Fidel

Source: European Food Research and Technology A, Volume 229, Number 1, May 2009 , pp. 93-98(6)

Publisher: Springer

Decreased Expression of T Lymphocyte Co-Stimulatory Molecule CD26 on Invariant Natural Killer T Cells in Systemic Lupus Erythematosus

Authors: Wong, P. T. Y.; Wong, C. K.; Tam, L. S.; Li, E. K.; Chen, D. P.; Lam, C. W. K.

Source: Immunological Investigations, Volume 38, Number 5, July 2009 , pp. 350-364(15)

Publisher: Informa Healthcare

Syzygium cumini inhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients

Authors: Bopp, A.; De Bona, K.S.; Bellé, L.P.; Moresco, R.N.; Moretto, M.B.

Source: Fundamental & Clinical Pharmacology, Volume 23, Number 4, August 2009 , pp. 501-507(7)

Publisher: Blackwell Publishing

Extracellular Proteases as Targets for Drug Development

Authors: Cudic, Mare; Fields, Gregg B.

Source: Current Protein and Peptide Science, Volume 10, Number 4, August 2009 , pp. 297-307(11)

Publisher: Bentham Science Publishers

Serum level of CD26 predicts time to first treatment in early B-chronic lymphocytic leukemia

Authors: Molica, Stefano; Digiesi, Giovanna; Mirabelli, Rosanna; Cutrona, Giovanna; Antenucci, Anna; Molica, Matteo; Giannarelli, Diana; Sperduti, Isabella; Morabito, Fortunato; Neri, Antonino; Baldini, Luca; Ferrarini, Manlio

Source: European Journal of Haematology, Volume 83, Number 3, September 2009 , pp. 208-214(7)

Publisher: Blackwell Publishing

CD26/DPPIV cell membrane expression and DPPIV activity in plasma of patients with acute leukemia

Authors: de Andrade, Camilla F. C. G.; Bigni, Ricardo; Pombo-de-Oliveira, Maria S.; Alves, Gilda; Pereira, Denise A.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 3, June 2009 , pp. 708-714(7)

Publisher: Informa Healthcare

Evaluation of the potential for steady-state pharmacokinetic and pharmacodynamic interactions between the DPP-4 inhibitor linagliptin and metformin in healthy subjects

Authors: Graefe-Mody, E. U.; Padula, S.; Ring, A.; Withopf, B.; Dugi, K. A.

Source: Current Medical Research and Opinion, Volume 25, Number 8, August 2009 , pp. 1963-1972(10)

Publisher: Informa Healthcare

Efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week study

Authors: Williams-Herman, Debora; Johnson, Jeremy; Teng, Rujun; Luo, Edmund; Davies, Michael J.; Kaufman, Keith D.; Goldstein, Barry J.; Amatruda, John M.

Source: Current Medical Research and Opinion, Volume 25, Number 3, March 2009 , pp. 569-583(15)

Publisher: Informa Healthcare

Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes*

Authors: He, Yan-Ling; Sabo, Ron; Picard, Franck; Wang, Yibin; Herron, Jerry; Ligueros-Saylan, Monica; Dole, William P.

Source: Current Medical Research and Opinion, Volume 25, Number 5, May 2009 , pp. 1265-1272(8)

Publisher: Informa Healthcare

Bone Marrow-Derived Progenitor Cells Could Modulate Pancreatic Cancer Tumorigenesis via Peritumoral Microenvironment in a Rat Model

Authors: Pan, Jen-Jung; Oh, Seh-Hoon; Lee, Wayne C.; Petersen, Bryon E.

Source: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, Volume 17, Number 8, 2009 , pp. 339-345(7)

Publisher: Cognizant Communication Corporation

Inhibitor of DASH proteases affects expression of adhesion molecules in osteoclasts and reduces myeloma growth and bone disease

Authors: Pennisi, Angela; Li, Xin; Ling, Wen; Khan, Sharmin; Gaddy, Dana; Suva, Larry J.; Barlogie, Bart; Shaughnessy, John D.; Aziz, Nazneen; Yaccoby, Shmuel

Source: British Journal of Haematology, Volume 145, Number 6, June 2009 , pp. 775-787(13)

Publisher: Blackwell Publishing

Progress in the Oral Treatment of Type 2 Diabetes: Update on DPP-IV Inhibitors

Authors: Salvatore, Teresa; Carbonara, Ornella; Cozzolino, Domenico; Torella, Roberto; Sasso, Ferdinando C.

Source: Current Diabetes Reviews, Volume 5, Number 2, May 2009 , pp. 92-101(10)

Publisher: Bentham Science Publishers

Irreversible Inhibition of Serine Proteases - Design and In Vivo Activity of Diaryl α-Aminophosphonate Derivatives

Authors: Sienczyk, M.; Oleksyszyn, J.

Source: Current Medicinal Chemistry, Volume 16, Number 13, May 2009 , pp. 1673-1687(15)

Publisher: Bentham Science Publishers