Search Results

Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model

Authors: You, Mi-Hyeon; Kim, Wang-Joon; Shim, Wooyoung; Lee, Sang-Rim; Lee, Gwang; Choi, Sangdun; Kim, Dae-Yong; Kim, Yong Man; Kim, Hyunsoo; Han, Sang-Uk

Source: Journal of Gastroenterology and Hepatology, Volume 24, Number 8, August 2009 , pp. 1393-1400(8)

Publisher: Blackwell Publishing

Radiosensitization and Anti-tumour Effects of Cytosine Deaminase and Thymidine Kinase Fusion Suicide Gene in Human Adenoid Cystic Carcinoma Cells

Authors: Huang, S-Y.; Zhang, D-S.; Han, J-Q.; Zhang, N.; Zhang, S-Z.; Mu, W-L.; Wei, F-C.

Source: The Journal of International Medical Research, Volume 37, Number 2, March 2009 , pp. 479-490(12)

Publisher: Field House Publishing

A novel method to generate unmarked gene deletions in the intracellular pathogen Rhodococcus equi using 5-fluorocytosine conditional lethality

Authors: van der Geize, R.; de Jong, W.; Hessels, G. I.; Grommen, A. W. F.; Jacobs, A. A. C.; Dijkhuizen, L.

Source: Nucleic Acids Research, Volume 36, Number 22, 3 December 2008 , pp. e151-e151(1)

Publisher: Oxford University Press

Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein

Authors: Xing, Ligang; Deng, Xuelong; Kotedia, Khushali; Ackerstaff, Ellen; Ponomarev, Vladimir; Clifton Ling, C.; Koutcher, Jason; Li, Gloria

Source: Acta Oncologica, Volume 47, Number 7, 2008 , pp. 1211-1220(10)

Publisher: Informa Healthcare

Improved effects of a double suicide gene system on prostate cancer cells by targeted regulation of prostate-specific membrane antigen promoter and enhancer

Authors: Zhang, Peng; Zeng, Hao; Wei, Qiang; Lu, Yiping; Li, Xiang; Wang, Jia; Zhao, Fujun; Li, Hong

Source: International Journal of Urology, Volume 15, Number 5, May 2008 , pp. 442-448(7)

Publisher: Blackwell Publishing

Gene Directed Enzyme Prodrug Therapy for Ovarian Cancer: Could GDEPT Become a Promising Treatment Against Ovarian Cancer?

Authors: Nawa, Akihiro; Tanino, Tadatoshi; Luo, Chen H.; Iwaki, Masahiro; Kajiyama, Hiroaki; Shibata, Kiyosumi; Yamamoto, Eiko; Ino, Kazuhiko; Nishiyama, Yukihiro; Kikkawa, Fumitaka

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 2, February 2008 , pp. 232-239(8)

Publisher: Bentham Science Publishers

Novel gene-directed enzyme prodrug therapies against prostate cancer

Authors: Russell, Pamela J; Khatri, Aparajita

Source: Expert Opinion on Investigational Drugs, Volume 15, Number 8, August 2006 , pp. 947-961(15)

Publisher: Informa Healthcare

Development and application of a positive–negative selectable marker system for use in reverse genetics in Plasmodium

Authors: Braks, Joanna A. M.; Franke-Fayard, Blandine; Kroeze, Hans; Janse, Chris J.; Waters, Andrew P.

Source: Nucleic Acids Research, Volume 34, Number 5, 2006 , pp. e39-e39(1)

Publisher: Oxford University Press

Procaspase-3 enhances the in vitro effect of cytosine deaminase–thymidine kinase disuicide gene therapy on human ovarian cancer

Authors: SONG; KONG; MA; QU; JIANG

Source: International Journal of Gynecological Cancer, Volume 16, Number 1, January 2006 , pp. 156-164(9)

Publisher: Blackwell Publishing

Development of Prodrugs for Enzyme-Mediated, Tumor-Selective Therapy

Authors: K. J. Yoon; Philip M. Potter; Mary K. Danks

Source: Current Medicinal Chemistry - Anti-Cancer Agents, Volume 5, Number 2, March 2005 , pp. 107-113(7)

Publisher: Bentham Science Publishers

Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy

Authors: Sheri D. Mahan; Greg C. Ireton; Catherine Knoeber; Barry L. Stoddard; Margaret E. Black

Source: Protein Engineering, Design and Selection, Volume 17, Number 8, 15 August 2004 , pp. 625-633(9)

Publisher: Oxford University Press

Apoptosis Induction With 5-Fluorocytosine/Cytosine Deaminase gene Therapy for Human Malignant Glioma Cells Mediated by Adenovirus

Authors: Kurozumi K.; Tamiya T.; Ono Y.; Otsuka S.; Kambara H.; Adachi Y.; Ichikawa T.; Hamada H.; Ohmoto T.

Source: Journal of Neuro-Oncology, Volume 66, Numbers 1-2, January 2004 , pp. 117-127(11)

Publisher: Springer

Enhanced suicide gene therapy by chimeric tumor-specific promoter based on HSF1 transcriptional regulation

Authors: Wang J.; Yao M.; Zhang Z.; Gu J.; Zhang Y.; Li B.; Sun L.; Liu X.

Source: FEBS Letters, Volume 546, Number 2, 10 July 2003 , pp. 315-320(6)

Publisher: Elsevier

Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model

Authors: Freytag S.O.; Paielli D.; Wing M.; Rogulski K.; Brown S.; Kolozsvary A.; Seely J.; Barton K.; Dragovic A.; Kim J.H.

Source: International Journal of Radiation Oncology*Biology*Physics, Volume 54, Number 3, 1 November 2002 , pp. 873-885(13)

Publisher: Elsevier

Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination

Authors: Duraisingh M.T.; Triglia T.; Cowman A.F.

Source: International Journal for Parasitology, Volume 32, Number 1, January 2002 , pp. 81-89(9)

Publisher: Elsevier

The Structure of Escherichia coli Cytosine Deaminase

Authors: Ireton G.C.; McDermott G.; Black M.E.; Stoddard B.L.

Source: Journal of Molecular Biology, Volume 315, Number 4, January 2002 , pp. 687-697(11)

Publisher: Academic Press

Quantitation of Cytosine Deaminase mRNA by Real-Time Reverse Transcription Polymerase Chain Reaction: A Sensitive Method for Assessing 5-Fluorocytosine Toxicity in Vitro

Authors: Miller C.R.; Gustin A.N.; Buchsbaum D.J.; Vickers S.M.; Manne U.; Grizzle W.E.; Cloud G.A.; Diasio R.B.; Johnson M.R.

Source: Analytical Biochemistry, Volume 301, Number 2, February 2002 , pp. 189-199(11)

Publisher: Academic Press

Cytotoxic effect of the cytosine deaminase gene delivered by the adenovirus vector in murine gastric cancer

Authors: Long, Cui; Yanzhen, Lin; Guoxiang, Jin; Dehong, Yu; Yue, Tu; Jun, Gao; Xuehua, Chen; Baoming, Yu

Source: Chinese Journal of Digestive Diseases, Volume 2, Number 1, March 2001 , pp. 1-4(4)

Publisher: Blackwell Publishing

Evaluation of the Acute and Subchronic Toxic Effects in Mice, Rats, and Monkeys of the Genetically Engineered and Escherichia coli Cytosine Deaminase Gene-Incorporated Salmonella Strain, TAPET-CD, Being Developed as an Antitumor Agent

Authors: Lee K.C.; Zheng L-M.; Margitich D.; Almassian B.; King I.

Source: International Journal of Toxicology, Volume 20, Number 4, 1 July 2001 , pp. 207-217(11)

Publisher: Informa Healthcare

Gene Therapy Enhances the Antiproliferative Effect of Radiation in Intimal Hyperplasia

Authors: Fortunato J.E.; Mauceri H.J.; Kocharyan H.; Song R.H.; Salloum R.; Vosicky J.; Swedberg K.; Malik S.; Abusharif F.; Glagov S.; Weichselbaum R.R.; Bassiouny H.S.

Source: Journal of Surgical Research, Volume 89, Number 2, April 2000 , pp. 155-162(8)

Publisher: Elsevier