Search Results

Semi-Mechanistic Population Pharmacokinetic Drug-Drug Interaction Modelling of a Long Half-Life Substrate and Itraconazole

Authors: Lehr, Thorsten; Staab, Alexander; Trommeshauser, Dirk; >Hans Guenter Schaefer,; Kloft, Charlotte

Source: Clinical Pharmacokinetics, Volume 49, Number 1, 1 January 2010 , pp. 53-66(14)

Publisher: Adis International

Effects of organic solvents on the time-dependent inhibition of CYP3A4 by diazepam

Authors: Nishiya, Y.; Nakamura, K.; Okudaira, N.; Abe, K.; Kobayashi, N.; Okazaki, O.

Source: Xenobiotica, Volume 40, Number 1, January 2010 , pp. 1-8(8)

Publisher: Informa Healthcare

CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes

Authors: Cao, Y.-F.; Zhang, Y.-Y.; Li, J.; Ge, G.-B.; Hu, D.; Liu, H.-X.; Huang, T.; Wang, Y.-C.; Fang, Z.-Z.; Sun, D.-X.; Huo, H.; Yin, J.; Yang, L.

Source: Xenobiotica, Volume 40, Number 1, January 2010 , pp. 38-47(10)

Publisher: Informa Healthcare

Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique

Authors: Ciccacci, Cinzia; Borgiani, Paola; Ceffa, Susanna; Sirianni, Elisabetta; Marazzi, Maria C; Altan, Anna M Doro; Paturzo, Giovanna; Bramanti, Placido; Novelli, Giuseppe; Palombi, Leonardo

Source: Pharmacogenomics, Volume 11, Number 1, January 2010 , pp. 23-31(9)

Publisher: Future Medicine

Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir

Authors: Andrews, Emma; Glue, Paul; Fang, Juanzhi; Crownover, Penelope; Tressler, Randall; Damle, Bharat

Source: British Journal of Clinical Pharmacology, Volume 69, Number 1, January 2010 , pp. 51-57(7)

Publisher: Blackwell Publishing

Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage

Authors: Miura, M.; Inoue, K.; Kagaya, H.; Saito, M.; Habuchi, T.; Satoh, S.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 939-945(7)

Publisher: Informa Healthcare

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

Authors: Scholz, Ina; Oberwittler, Heike; Riedel, Klaus-Dieter; Burhenne, Jürgen; Weiss, Johanna; Haefeli, Walter E.; Mikus, Gerd

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 906-915(10)

Publisher: Blackwell Publishing

Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo

Authors: Bae, Soo H.; Bae, Soo K.; Lee, Myung G.

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 12, December 2009 , pp. 1637-1642(6)

Publisher: Pharmaceutical Press

Effect of fluconazole on the pharmacokinetics of halofantrine in healthy volunteers

Authors: Babalola, C. P.; Kolade, Y. T.; Olaniyi, A. A.; Adedapo, A.; Scriba, G. K. E.

Source: Journal of Clinical Pharmacy & Therapeutics, Volume 34, Number 6, December 2009 , pp. 677-682(6)

Publisher: Blackwell Publishing

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans

Authors: Mukonzo, Jackson K.; Röshammar, Daniel; Waako, Paul; Andersson, Maria; Fukasawa, Takashi; Milani, Lili; Svensson, Jan Olof; Ogwal-Okeng, Jasper; Gustafsson, Lars L.; Aklillu, Eleni

Source: British Journal of Clinical Pharmacology, Volume 68, Number 5, November 2009 , pp. 690-699(10)

Publisher: Blackwell Publishing

Inhibition of the active principle of the weak opioid tilidine by the triazole antifungal voriconazole

Authors: Grün, Barbara; Krautter, Stefanie; Riedel, Klaus-Dieter; Mikus, Gerd

Source: British Journal of Clinical Pharmacology, Volume 68, Number 5, November 2009 , pp. 712-720(9)

Publisher: Blackwell Publishing

The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

Authors: Muschler, Eugen; Lal, Jawahar; Jetter, Alexander; Rattay, Anke; Zanger, Ulrich; Zadoyan, Gregor; Fuhr, Uwe; Kirchheiner, Julia

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 6, December 2009 , pp. 374-379(6)

Publisher: Blackwell Publishing

Oxidation of Endobiotics Mediated by Xenobiotic-Metabolizing Forms of Human Cytochrome P450

Authors: Niwa, Toshiro; Murayama, Norie; Yamazaki, Hiroshi

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 700-712(13)

Publisher: Bentham Science Publishers

Insights into the Structure, Function, and Regulation of Human Cytochrome P450 1A2

Authors: Zhou, Shu-Feng; Yang, Li-Ping; Wei, Ming Q.; Duan, Wei; Chan, Eli

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 713-729(17)

Publisher: Bentham Science Publishers

Substrate Specificity, Regulation, and Polymorphism of Human Cytochrome P450 2B6

Authors: Mo, Sui-Lin; Liu, Ya-He; Duan, Wei; Wei, Ming Q.; Kanwar, Jagat R.; Zhou, Shu-Feng

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 730-753(24)

Publisher: Bentham Science Publishers

Human Exposure to Triclosan via Toothpaste does not change CYP3A4 Activity or Plasma Concentrations of Thyroid Hormones

Authors: Allmyr, Mats; Panagiotidis, Georgios; Sparve, Erik; Diczfalusy, Ulf; Sandborgh-Englund, Gunilla

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 5, November 2009 , pp. 339-344(6)

Publisher: Blackwell Publishing

In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation

Authors: Chetty, Manoranjenni; d'Esposito, Fabrizio; Zhang, Wei V.; Glen, John; Dore, Glenys; Stankovic, Zvijezdana; Edwards, Robert J.; Ramzan, Iqbal; Murray, Michael

Source: British Journal of Clinical Pharmacology, Volume 68, Number 4, October 2009 , pp. 574-579(6)

Publisher: Blackwell Publishing

Effects of rifampicin on the pharmacokinetics of roflumilast and roflumilast N-oxide in healthy subjects

Authors: Nassr, Nassr; Huennemeyer, Andreas; Herzog, Rolf; von Richter, Oliver; Hermann, Robert; Koch, Manuela; Duffy, Kevin; Zech, Karl; Lahu, Gezim

Source: British Journal of Clinical Pharmacology, Volume 68, Number 4, October 2009 , pp. 580-587(8)

Publisher: Blackwell Publishing

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

Authors: Wang, Bo; Yang, Li-Ping; Zhang, Xiao-Zhuang; Huang, Shui-Qing; Bartlam, Mark; Zhou, Shu-Feng

Source: Drug Metabolism Reviews, Volume 41, Number 4, November 2009 , pp. 573-643(71)

Publisher: Informa Healthcare

Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients

Authors: Elens, Laure; Yombi, Jean-Cyr; Lison, Dominique; Wallemacq, Pierre; Vandercam, Bernard; Haufroid, Vincent

Source: Pharmacogenomics, Volume 10, Number 10, October 2009 , pp. 1589-1597(9)

Publisher: Future Medicine