Search Results

New Bisquaternary Isoquinolinium Inhibitors of Brain Cholinesterases - Synthesis and Anticholinesterase Activity

Authors: Binder, Jiri; Paar, Martin; Jun, Daniel; Pohanka, Miroslav; Hrabinova, Martina; Opletalova, Veronika; Kuca, Kamil

Source: Letters in Drug Design & Discovery, Volume 7, Number 1, January 2010 , pp. 1-4(4)

Publisher: Bentham Science Publishers

Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology

Authors: Leduc, Valérie; Théroux, Louise; Dea, Doris; Robitaille, Yves; Poirier, Judes

Source: European Journal of Neuroscience, Volume 30, Number 9, November 2009 , pp. 1823-1830(8)

Publisher: Blackwell Publishing

The NADPH oxidase inhibitor diphenyleneiodonium is also a potent inhibitor of cholinesterases and the internal Ca²⁺ pump

Authors: Tazzeo, T; Worek, F; Janssen, LJ

Source: British Journal of Pharmacology, Volume 158, Number 3, October 2009 , pp. 790-796(7)

Publisher: Blackwell Publishing

Molecular dynamics simulation of Axillaridine-A: A potent natural cholinesterase inhibitor

Authors: ul-Haq, Zaheer; Hadi, Hassan; Moin, Syed Tarique; Iqbal Choudhary, M.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 5, October 2009 , pp. 1101-1105(5)

Publisher: Informa Healthcare

Increased colonic transit in rats produced by a combination of a cholinesterase inhibitor with a 5-HT₄ receptor agonist

Authors: campbell-dittmeyer, k.; hicks, g. a.; earnest, d. l.; greenwood-van meerveld, b.

Source: Neurogastroenterology and Motility, Volume 21, Number 11, November 2009 , pp. 1197-e108(-1196)

Publisher: Blackwell Publishing

Effects of cholinesterase inhibition in supraspinal and spinal neural pathways on the micturition reflex in rats

Authors: Masuda, Hitoshi; Chancellor, Michel B.; Kihara, Kazunori; Sakai, Yasuyuki; Koga, Fumitaka; Azuma, Hiroshi; de Groat, William C.; Yoshimura, Naoki

Source: BJU International, Volume 104, Number 8, October 2009 , pp. 1163-1169(7)

Publisher: Blackwell Publishing

Retrospective population pharmacokinetic/pharmacodynamic analysis of pyridostigmine, a cholinesterase inhibitor, in Chinese males

Authors: Seng, Kok-Yong; Loke, Weng-Keong; Moochhala, Shabbir; Zhao, Bin; Lee, Jon-Deoon Edmund

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 9, September 2009 , pp. 1187-1196(10)

Publisher: Pharmaceutical Press

Preparation and In Vitro Evaluation of Monoquaternary Inhibitors of Brain Cholinesterases

Authors: Jun, Daniel; Paar, Martin; Binder, Jiri; Marek, Jan; Pohanka, Miroslav; Stodulka, Petr; Kuca, Kamil

Source: Letters in Organic Chemistry, Volume 6, Number 6, September 2009 , pp. 500-503(4)

Publisher: Bentham Science Publishers

A cost-effectiveness study has added fuel to the debate over the UK's decision to restrict cholinesterase inhibitor use to moderate Alzheimer's disease (AD).

Source: PharmacoEconomics and Outcomes News, Volume 1, Number 584, 2009-08-08 , pp. 5-5(1)

Publisher: Adis International

Concomitant Use of Anticholinergics with Acetylcholinesterase Inhibitors in Medicaid Recipients with Dementia and Residing in Nursing Homes

Authors: Modi, Ankita; Weiner, Michael; Craig, Bruce A.; Sands, Laura P.; Rosenman, Marc B.; Thomas, Joseph

Source: Journal of the American Geriatrics Society, Volume 57, Number 7, July 2009 , pp. 1238-1244(7)

Publisher: Blackwell Publishing

The serotonin 5-HT₆ receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease

Authors: Geldenhuys, Werner J; Van der Schyf, Cornelis J

Source: Expert Review of Neurotherapeutics, Volume 9, Number 7, July 2009 , pp. 1073-1085(13)

Publisher: Expert Reviews

5-hydroxyindalpine, an agonist at the putative 5-HT_1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon

Authors: mitchell, n. a.; pepperell, e.; ociepka, s.; brown, j. d.; witherington, j.; tuladhar, b.; sanger, g. j.; lee, k.; cellek, s.

Source: Neurogastroenterology and Motility, Volume 21, Number 7, July 2009 , pp. 760-e48(-759)

Publisher: Blackwell Publishing

Persistence with Cholinesterase Inhibitor Therapy for Dementia: An Observational Administrative Health Database Study

Authors: Herrmann, Nathan; Binder, Carin; Dalziel, William; Smyth, Steve; Camacho, Fernando

Source: Drugs & Aging, Volume 26, Number 5, May 5 2009 , pp. 403-407(5)

Publisher: Adis International

Donepezil in the treatment of patients with Alzheimer's disease

Author: Tsuno, Norifumi

Source: Expert Review of Neurotherapeutics, Volume 9, Number 5, May 2009 , pp. 591-598(8)

Publisher: Expert Reviews

Progress of Biosensors Based on Cholinesterase Inhibition

Authors: Pohanka, Miroslav; Musilek, Kamil; Kuca, Kamil

Source: Current Medicinal Chemistry, Volume 16, Number 14, May 2009 , pp. 1790-1798(9)

Publisher: Bentham Science Publishers

The cholinesterase inhibitor physostigmine for the local treatment of dry mouth: a randomized study

Authors: Khosravani, Nina; Birkhed, Dowen; Ekström, Jörgen

Source: European Journal of Oral Sciences, Volume 117, Number 3, June 2009 , pp. 209-217(9)

Publisher: Blackwell Publishing

Novel Convenient Synthesis of Rivastigmine

Authors: Hu, Meng; Zhang, Fu-Li; Xie, Mei-Hua

Source: Synthetic Communications, Volume 39, Number 9, January 2009 , pp. 1527-1533(7)

Publisher: Taylor and Francis Ltd

Galantamine-induced improvements in cognitive function are not related to alterations in α₄β₂ nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[¹⁸F]Fluoro-A-85380 PET

Authors: Ellis, J.; Nathan, P.; Villemagne, V.; Mulligan, R.; Saunder, T.; Young, K.; Smith, C.; Welch, J.; Woodward, M.; Wesnes, K.; Savage, G.; Rowe, C.

Source: Psychopharmacology, Volume 202, Numbers 1-3, January 2009 , pp. 79-91(13)

Publisher: Springer

Responders to ChEI Treatment of Alzheimer's Disease Show Restitution of Normal Regional Cortical Activation

Authors: Venneri, Annalena; McGeown, William J.; Shanks, Michael F.

Source: Current Alzheimer Research, Volume 6, Number 2, April 2009 , pp. 97-111(15)

Publisher: Bentham Science Publishers

Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease

Authors: Smith, Gwenn S.; Kramer, Elisse; Ma, Yilong; Hermann, Carol R.; Dhawan, Vijay; Chaly, Thomas; Eidelberg, David

Source: Brain, Volume 132, Number 2, 5 February 2009 , pp. 392-401(10)

Publisher: Oxford University Press