Search Results

The chemokine receptor antagonist, TAK-779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function

Authors: Ni, Jia; Zhu, Yi-Na; Zhong, Xiang-Gen; Ding, Yu; Hou, Li-Fei; Tong, Xian-Kun; Tang, Wei; Ono, Shiro; Yang, Yi-Fu; Zuo, Jian-Ping

Source: British Journal of Pharmacology, Volume 158, Number 8, December 2009 , pp. 2046-2056(11)

Publisher: Blackwell Publishing

A crucial role for TNF-α in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5

Authors: Vieira, SM; Lemos, HP; Grespan, R; Napimoga, MH; Dal-Secco, D; Freitas, A; Cunha, TM; Verri Jr, WA; Souza-Junior, DA; Jamur, MC; Fernandes, KS; Oliver, C; Silva, JS; Teixeira, MM; Cunha, FQ

Source: British Journal of Pharmacology, Volume 158, Number 3, October 2009 , pp. 779-789(11)

Publisher: Blackwell Publishing

Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A₁ receptors

Authors: Valério, DA; Ferreira, FI; Cunha, TM; Alves-Filho, JC; Lima, FO; De Oliveira, JR; Ferreira, SH; Cunha, FQ; Queiroz, RH; Verri Jr, WA

Source: British Journal of Pharmacology, Volume 158, Number 2, September 2009 , pp. 558-568(11)

Publisher: Blackwell Publishing

Pulmonary Inflammation and Airway Hyperresponsiveness in a Mouse Model of Asthma Complicated by Acid Aspiration

Authors: Nemzek, Jean A.; Kim, Jiyoun

Source: Comparative Medicine, Volume 59, Number 4, August 2009 , pp. 321-330(10)

Publisher: American Association for Laboratory Animal Science

SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor

Authors: Bradley, ME; Bond, ME; Manini, J; Brown, Z; Charlton, SJ

Source: British Journal of Pharmacology, Volume 158, Number 1, September 2009 , pp. 328-338(11)

Publisher: Blackwell Publishing

Morphine enhances Tat-induced activation in murine microglia

Authors: Bokhari, Sirosh; Yao, Honghong; Bethel-Brown, Crystal; Fuwang, Peng; Williams, Rachel; Dhillon, Navneet; Hegde, Ramakrishna; Kumar, Anil; Buch, Shilpa

Source: Journal of NeuroVirology, Volume 15, Number 3, June 2009 , pp. 219-228(10)

Publisher: Informa Healthcare

Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients

Authors: Vandekerckhove, Linos; Verhofstede, Chris; Vogelaers, Dirk

Source: Journal of Antimicrobial Chemotherapy, Volume 63, Number 6, 30 June 2009 , pp. 1087-1096(10)

Publisher: Oxford University Press

3D-Pharmacophere Models for CC Chemokine Receptor 1 Antagonists

Authors: Liu, Yixi; Andre, Philippe; Wei, Jing; Zhao, Kang

Source: Medicinal Chemistry, Volume 5, Number 4, July 2009 , pp. 318-324(7)

Publisher: Bentham Science Publishers

Physiological evidence for interaction between the HIV-1 co-receptor CXCR4 and the cannabinoid system in the brain

Authors: Benamar, Khalid; Yondorf, Menachem; Geller, Ellen B; Eisenstein, Toby K; Adler, Martin W

Source: British Journal of Pharmacology, Volume 157, Number 7, August 2009 , pp. 1225-1231(7)

Publisher: Blackwell Publishing

CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway

Authors: Wu, Yumei; Peng, Hui; Cui, Min; Whitney, Nicholas P.; Huang, Yunlong; Zheng, Jialin C.

Source: Journal of Neurochemistry, Volume 109, Number 4, May 2009 , pp. 1157-1167(11)

Publisher: Blackwell Publishing

Recent developments in CCR2 antagonists

Authors: Xia, Mingde; Sui, Zhihua

Source: Expert Opinion on Therapeutic Patents, Volume 19, Number 3, March 2009 , pp. 295-303(9)

Publisher: Informa Healthcare

Selective CB1 cannabinoid receptor antagonist, SR141716A, attenuates liver injury induced by Concanavalin A

Authors: Kojima, Midori; Kato, Naoto; Hirano, Daisuke; Ochi, Takashi; Nii, Aisuke; Shinjo, Katsuhiro; Eda, Hiroyuki

Source: Hepatology Research, Volume 39, Number 4, April 2009 , pp. 408-414(7)

Publisher: Blackwell Publishing

The chemokine system and CCR5 antagonists: potential in HIV treatment and other novel therapies

Authors: Dhami, H.; Fritz, C. E.; Gankin, B.; Pak, S. H.; Yi, W.; Seya, M.-J.; Raffa, R. B.; Nagar, S.

Source: Journal of Clinical Pharmacy & Therapeutics, Volume 34, Number 2, April 2009 , pp. 147-160(14)

Publisher: Blackwell Publishing

Chemokine Receptors as Targets for Cancer Therapy

Authors: Wu, Xuesong; Lee, Vivian C.; Chevalier, Eric; Hwang, Sam T.

Source: Current Pharmaceutical Design, Volume 15, Number 7, March 2009 , pp. 742-757(16)

Publisher: Bentham Science Publishers

Investigation of the Structural Requirement for Blocking the Human CCR5 Chemokine Receptor. An Insight from Quantitative Structure Activity Relationships Study

Author: Dessalew, Nigus

Source: Letters in Drug Design & Discovery, Volume 6, Number 2, March 2009 , pp. 114-124(11)

Publisher: Bentham Science Publishers

Antiviral activity and safety of aplaviroc, a CCR5 antagonist, in combination with lopinavir/ritonavir in HIV-infected, therapy-naïve patients: results of the EPIC study (CCR100136)

Authors: Yeni, P; LaMarca, A; Berger, D; Cimoch, P; Lazzarin, A; Salvato, P; Smaill, FM; Teofilo, E; Madison, SJ; Nichols, WG; Adkison, KK; Bonny, T; Millard, J; McCarty, D

Source: HIV Medicine, Volume 10, Number 2, February 2009 , pp. 116-124(9)

Publisher: Blackwell Publishing

Chemokine receptor antagonists: part 2

Authors: Pease, James E; Horuk, Richard

Source: Expert Opinion on Therapeutic Patents, Volume 19, Number 2, February 2009 , pp. 199-221(23)

Publisher: Informa Healthcare

The Chemokine CCL5 Is Essential for Leukocyte Recruitment in a Model of Severe Herpes simplex Encephalitis

Authors: Vilela, Márcia Carvalho; Mansur, Daniel Santos; Lacerda-Queiroz, Norinne; Rodrigues, David Henrique; Lima, Graciela Kunrath; Arantes, Rosa Maria Esteves; Kroon, Erna Geessien; da Silva Campos, Marco Antônio; Teixeira, Mauro Martins; Teixeira, Antônio Lúcio

Source: Annals of the New York Academy of Sciences, Volume 1153, Number 1, February 2009 , pp. 256-263(8)

Publisher: Blackwell Publishing

Activation of P2X₇ receptors induces CCL3 production in microglial cells through transcription factor NFAT

Authors: Kataoka, Ayako; Tozaki-Saitoh, Hidetoshi; Koga, Yui; Tsuda, Makoto; Inoue, Kazuhide

Source: Journal of Neurochemistry, Volume 108, Number 1, January 2009 , pp. 115-125(11)

Publisher: Blackwell Publishing

HAART in treatment-experienced patients in the 21st century: the audacity of hope

Author: Conway, Brian

Source: Future Virology, Volume 4, Number 1, January 2009 , pp. 39-41(3)

Publisher: Future Medicine