Search Results

MS-1020 is a novel small molecule that selectively inhibits JAK3 activity

Authors: Kim, Byung-Hak; Oh, Sei-Ryang; Yin, Chang-Hong; Lee, Sangku; Kim, Eun-Ah; Kim, Min-Seok; Sandoval, Claudio; Jayabose, Somasundaram; Bach, Erika A.; Lee, Hyeong-Kyu; Baeg, Gyeong-Hun

Source: British Journal of Haematology, Volume 148, Number 1, January 2010 , pp. 132-143(12)

Publisher: Blackwell Publishing

Serum testosterone bioassay evaluation in a large male cohort

Authors: Need, Eleanor F.; O'Loughlin, Peter D.; Armstrong, David T.; Haren, Matthew T.; Martin, Sean A.; Tilley, Wayne D.; Wittert, Gary A.; Buchanan, Grant

Source: Clinical Endocrinology, Volume 72, Number 1, January 2010 , pp. 87-98(12)

Publisher: Blackwell Publishing

Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions

Authors: Sharma, P.; Holmes, V. E.; Elsby, R.; Lambert, C.; Surry, D.

Source: Xenobiotica, Volume 40, Number 1, January 2010 , pp. 24-37(14)

Publisher: Informa Healthcare

Characterizing functional stem cell-cardiomyocyte interactions

Authors: Bursac, Nenad; Kirkton, Robert D; McSpadden, Luke C; Liau, Brian

Source: Regenerative Medicine, Volume 5, Number 1, January 2010 , pp. 87-105(19)

Publisher: Future Medicine

2-Arylbenzimidazoles as Antiviral and Antiproliferative Agents-Part 2

Authors: Vitale, Gabriella; Corona, Paola; Loriga, Mario; Carta, Antonio; Paglietti, Giuseppe; Colla, Paolo L.; Busonera, Bernardetta; Marongiu, Esther; Collu, David; Loddo, Roberta

Source: Medicinal Chemistry, Volume 5, Number 6, November 2009 , pp. 507-516(10)

Publisher: Bentham Science Publishers

Conference Report: Update on screening methodologies

Authors: Bardera, Ana Isabel; Martin, Julio

Source: Future Medicinal Chemistry, Volume 1, Number 2, May 2009 , pp. 253-256(4)

Publisher: Future Science

Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties

Authors: Hegedűs, C; Özvegy-Laczka, C; Apáti, Á; Magócsi, M; Német, K; Őrfi, L; Kéri, G; Katona, M; Takáts, Z; Váradi, A; Szakács, G; Sarkadi, B

Source: British Journal of Pharmacology, Volume 158, Number 4, October 2009 , pp. 1153-1164(12)

Publisher: Blackwell Publishing

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity

Authors: Beher, Dirk; Wu, John; Cumine, Suzanne; Kim, Ki Won; Lu, Shu-Chen; Atangan, Larissa; Wang, Minghan

Source: Chemical Biology & Drug Design, Volume 74, Number 6, December 2009 , pp. 619-624(6)

Publisher: Blackwell Publishing

Improvement of a dendritic cell-based tumour vaccine by an influenza virus

Authors: Sachet, M.; Friedl, J.; Hassler, M.; Ploder, M.; Stary, G.; Stift, A.; Bergmann, M.

Source: European Journal of Clinical Investigation, Volume 39, Number 11, November 2009 , pp. 1000-1009(10)

Publisher: Blackwell Publishing

Development of Extracellular Signal-Regulated Kinase Inhibitors

Authors: Burkhard, Kimberly; Smith, Sarice; Deshmukh, Rahul; MacKerell Jr., Alexander D.; Shapiro, Paul

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 8, May 2009 , pp. 678-689(12)

Publisher: Bentham Science Publishers

Comparative characterization of bone marrow-derived mesenchymal stromal cells from four different rat strains

Authors: Barzilay, Ran; Sadan, Ofer; Melamed, Eldad; Offen, Daniel

Source: Cytotherapy, Volume 11, Number 4, July 2009 , pp. 435-442(8)

Publisher: Informa Healthcare

Editorial [Hot topic: Label-Free Detection Technologies (Guest Editor: John D. McCarter)]

Author: McCarter, John D.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 8, September 2009 , pp. 740-740(1)

Publisher: Bentham Science Publishers

High Throughput Cell-Based Screening of Biodegradable Polyanhydride Libraries

Authors: Adler, Andrew F.; Petersen, Latrisha K.; Wilson, Jennifer H.; Torres, Maria P.; Thorstenson, Jon B.; Gardner, Stuart W.; Mallapragada, Surya K.; Wannemuehler, Michael J.; Narasimhan, Balaji

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 7, August 2009 , pp. 634-645(12)

Publisher: Bentham Science Publishers

Label-free optical biosensor: A tool for G protein-coupled receptors pharmacology profiling and inverse agonists identification

Author: Lee, Paul H.

Source: Journal of Receptors and Signal Transduction, Volume 29, Numbers 3-4, August 2009 , pp. 146-153(8)

Publisher: Informa Healthcare

Real-time quantitation of viral replication and inhibitor potency using a label-free optical biosensor

Authors: Owens, Róisín M.; Wang, ChangQing; You, Juyoung A.; Jiambutr, Jantorn; S.L. Xu, Arron; Marala, Ravi B.; Jin, Moonsoo M.

Source: Journal of Receptors and Signal Transduction, Volume 29, Numbers 3-4, August 2009 , pp. 195-201(7)

Publisher: Informa Healthcare

Differential effects of γ-secretase and BACE1 inhibition on brain Aβ levels in vitro and in vivo

Authors: Elvang, Anders Brandt; Volbracht, Christiane; Pedersen, Lars Østergaard; Jensen, Klaus Gjervig; Karlsson, Jens-Jakob; Larsen, Stine Anna; Mørk, Arne; Stensbøl, Tine Bryan; Bastlund, Jesper Frank

Source: Journal of Neurochemistry, Volume 110, Number 5, September 2009 , pp. 1377-1387(11)

Publisher: Blackwell Publishing

Drug-Like Property Concepts in Pharmaceutical Design

Authors: Di, Li; Kerns, Edward H.; Carter, Guy T.

Source: Current Pharmaceutical Design, Volume 15, Number 19, July 2009 , pp. 2184-2194(11)

Publisher: Bentham Science Publishers

In vitro cell-based assay for activity analysis of staphylococcal enterotoxin A in food

Authors: Rasooly, Reuven; Do, Paula M.

Source: FEMS Immunology & Medical Microbiology, Volume 56, Number 2, July 2009 , pp. 172-178(7)

Publisher: Blackwell Publishing

An overview of cell phenotypes in HCS: limitations and advantages

Author: Gasparri, Fabio

Source: Expert Opinion on Drug Discovery, Volume 4, Number 6, June 2009 , pp. 643-657(15)

Publisher: Informa Healthcare

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

Authors: Mazzoleni, Giovanna; Di Lorenzo, D.; Steimberg, N.

Source: Genes & Nutrition, Volume 4, Number 1, March 2009 , pp. 13-22(10)

Publisher: Springer