Search Results

Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model

Authors: You, Mi-Hyeon; Kim, Wang-Joon; Shim, Wooyoung; Lee, Sang-Rim; Lee, Gwang; Choi, Sangdun; Kim, Dae-Yong; Kim, Yong Man; Kim, Hyunsoo; Han, Sang-Uk

Source: Journal of Gastroenterology and Hepatology, Volume 24, Number 8, August 2009 , pp. 1393-1400(8)

Publisher: Blackwell Publishing

Radiosensitization and Anti-tumour Effects of Cytosine Deaminase and Thymidine Kinase Fusion Suicide Gene in Human Adenoid Cystic Carcinoma Cells

Authors: Huang, S-Y.; Zhang, D-S.; Han, J-Q.; Zhang, N.; Zhang, S-Z.; Mu, W-L.; Wei, F-C.

Source: The Journal of International Medical Research, Volume 37, Number 2, March 2009 , pp. 479-490(12)

Publisher: Field House Publishing

A novel method to generate unmarked gene deletions in the intracellular pathogen Rhodococcus equi using 5-fluorocytosine conditional lethality

Authors: van der Geize, R.; de Jong, W.; Hessels, G. I.; Grommen, A. W. F.; Jacobs, A. A. C.; Dijkhuizen, L.

Source: Nucleic Acids Research, Volume 36, Number 22, 3 December 2008 , pp. e151-e151(1)

Publisher: Oxford University Press

Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein

Authors: Xing, Ligang; Deng, Xuelong; Kotedia, Khushali; Ackerstaff, Ellen; Ponomarev, Vladimir; Clifton Ling, C.; Koutcher, Jason; Li, Gloria

Source: Acta Oncologica, Volume 47, Number 7, 2008 , pp. 1211-1220(10)

Publisher: Informa Healthcare

Apoptotic Induction with Bifunctional E.coli Cytosine Deaminase-Uracil Phosphoribosyltransferase Mediated Suicide Gene Therapy is Synergized by Curcumin Treatment In vitro

Authors: Gopinath, P.; Ghosh, Siddhartha

Source: Molecular Biotechnology, Volume 39, Number 1, May 2008 , pp. 39-48(10)

Publisher: Humana Press

Improved effects of a double suicide gene system on prostate cancer cells by targeted regulation of prostate-specific membrane antigen promoter and enhancer

Authors: Zhang, Peng; Zeng, Hao; Wei, Qiang; Lu, Yiping; Li, Xiang; Wang, Jia; Zhao, Fujun; Li, Hong

Source: International Journal of Urology, Volume 15, Number 5, May 2008 , pp. 442-448(7)

Publisher: Blackwell Publishing

Targeted suicide gene therapy for small cell lung cancer

Authors: Pedersen, Nina; Poulsen, Hans Skovgaard; Christensen, Camilla Laulund

Source: Apmis, Volume 116, Number 5, May 2008 , pp. 412-413(2)

Publisher: Blackwell Publishing

Antitumor effects of cytosine deaminase and thymidine kinase fusion suicide gene under the control of mdr1 promoter in mdr1 positive leukemia cells

Authors: Wang, Xiangling; Ji, Chunyan; Ma, Daoxin; Zhao, Jianqiang; Hou, Ming; Yu, Haiqing; Zang, Shaolei

Source: Leukemia and Lymphoma, Volume 48, Number 8, August 2007 , pp. 1600-1609(10)

Publisher: Informa Healthcare

Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats

Authors: Sasaki, Takayuki; Fujimori, Minoru; Hamaji, Yoshinori; Hama, Yoshihisa; Ito, Ken-ichi; Amano, Jun; Taniguchi, Shun'ichiro

Source: Cancer Science, Volume 97, Number 7, July 2006 , pp. 649-657(9)

Publisher: Blackwell Publishing

Procaspase-3 enhances the in vitro effect of cytosine deaminase–thymidine kinase disuicide gene therapy on human ovarian cancer

Authors: SONG; KONG; MA; QU; JIANG

Source: International Journal of Gynecological Cancer, Volume 16, Number 1, January 2006 , pp. 156-164(9)

Publisher: Blackwell Publishing

Antitumor effect of cytosine deaminase/5-fluorocytosine suicide gene therapy system mediated by Bifidobacterium infantis on melanoma

Authors: YI, Cheng; HUANG, Ying; GUO, Zhi-ying; WANG, Shu-ren

Source: Acta Pharmacologica Sinica, Volume 26, Number 5, May 2005 , pp. 629-634(6)

Publisher: Blackwell Publishing

Development of Prodrugs for Enzyme-Mediated, Tumor-Selective Therapy

Authors: K. J. Yoon; Philip M. Potter; Mary K. Danks

Source: Current Medicinal Chemistry - Anti-Cancer Agents, Volume 5, Number 2, March 2005 , pp. 107-113(7)

Publisher: Bentham Science Publishers

Apoptosis Induction With 5-Fluorocytosine/Cytosine Deaminase gene Therapy for Human Malignant Glioma Cells Mediated by Adenovirus

Authors: Kurozumi K.; Tamiya T.; Ono Y.; Otsuka S.; Kambara H.; Adachi Y.; Ichikawa T.; Hamada H.; Ohmoto T.

Source: Journal of Neuro-Oncology, Volume 66, Numbers 1-2, January 2004 , pp. 117-127(11)

Publisher: Springer

Potential benefits of combining cytosine deaminase/5-fluorocytosine gene therapy and irradiation for prostate cancer: Experimental study

Authors: KATO H.; KOSHIDA K.; YOKOYAMA K.; MIZOKAMI A.; NAMIKI M.

Source: International Journal of Urology, Volume 9, Number 10, October 2002 , pp. 567-576(10)

Publisher: Blackwell Publishing

Quantitation of Cytosine Deaminase mRNA by Real-Time Reverse Transcription Polymerase Chain Reaction: A Sensitive Method for Assessing 5-Fluorocytosine Toxicity in Vitro

Authors: Miller C.R.; Gustin A.N.; Buchsbaum D.J.; Vickers S.M.; Manne U.; Grizzle W.E.; Cloud G.A.; Diasio R.B.; Johnson M.R.

Source: Analytical Biochemistry, Volume 301, Number 2, February 2002 , pp. 189-199(11)

Publisher: Academic Press

Cytotoxic effect of the cytosine deaminase gene delivered by the adenovirus vector in murine gastric cancer

Authors: Long, Cui; Yanzhen, Lin; Guoxiang, Jin; Dehong, Yu; Yue, Tu; Jun, Gao; Xuehua, Chen; Baoming, Yu

Source: Chinese Journal of Digestive Diseases, Volume 2, Number 1, March 2001 , pp. 1-4(4)

Publisher: Blackwell Publishing

Evaluation of the Acute and Subchronic Toxic Effects in Mice, Rats, and Monkeys of the Genetically Engineered and Escherichia coli Cytosine Deaminase Gene-Incorporated Salmonella Strain, TAPET-CD, Being Developed as an Antitumor Agent

Authors: Lee K.C.; Zheng L-M.; Margitich D.; Almassian B.; King I.

Source: International Journal of Toxicology, Volume 20, Number 4, 1 July 2001 , pp. 207-217(11)

Publisher: Informa Healthcare

Suicide gene therapy on LNCaP human prostate cancer cells

Authors: Yoshimura I.; Suzuki S.; Tadakuma T.; Hayakawa M.

Source: International Journal of Urology, Volume 8, Number 7, July 2001 , pp. S5-S8(4)

Publisher: Blackwell Publishing

Evaluation of the Biodistribution, Persistence, Toxicity, and Potential of Germ-Line Transmission of a Replication-Competent Human Adenovirus Following Intraprostatic Administration in the Mouse

Authors: Paielli D.L.; Wing M.S.; Rogulski K.R.; Gilbert J.D.; Kolozsvary A.; Kim J.H.; Hughes J.; Schnell M.; Thompson T.; Freytag S.O.

Source: Molecular Therapy, Volume 1, Number 3, March 2000 , pp. 263-274(12)

Publisher: Elsevier

Gene Therapy Enhances the Antiproliferative Effect of Radiation in Intimal Hyperplasia

Authors: Fortunato J.E.; Mauceri H.J.; Kocharyan H.; Song R.H.; Salloum R.; Vosicky J.; Swedberg K.; Malik S.; Abusharif F.; Glagov S.; Weichselbaum R.R.; Bassiouny H.S.

Source: Journal of Surgical Research, Volume 89, Number 2, April 2000 , pp. 155-162(8)

Publisher: Elsevier