Search Results

Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice

Authors: Cool, Bethany H.; Zitnik, Galynn; Martin, George M.; Hu, Qubai

Source: Journal of Neurochemistry, Volume 112, Number 2, January 2010 , pp. 410-419(10)

Publisher: Blackwell Publishing

Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model

Authors: Choi, Jennifer H. K.; Berger, Jason D.; Mazzella, Matthew J.; Morales-Corraliza, Jose; Cataldo, Anne M.; Nixon, Ralph A.; Ginsberg, Stephen D.; Levy, Efrat; Mathews, Paul M.

Source: Journal of Neurochemistry, Volume 110, Number 6, September 2009 , pp. 1818-1827(10)

Publisher: Blackwell Publishing

Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice

Authors: Cohen, A. D.; Ikonomovic, M. D.; Abrahamson, E. E.; Paljug, W. R.; DeKosky, S. T.; Lefterov, I. M.; Koldamova, R. P.; Shao, L.; Debnath, M. L.; Mason, N. S.; Mathis, C. A.; Klunk, W. E.

Source: Letters in Drug Design & Discovery, Volume 6, Number 6, September 2009 , pp. 437-444(8)

Publisher: Bentham Science Publishers

ADAM19/Adamalysin 19 Structure, Function, and Role as a Putative Target in Tumors and Inflammatory Diseases

Authors: Qi, Bin; Newcomer, Robert G.; Sang, Qing-Xiang A.

Source: Current Pharmaceutical Design, Volume 15, Number 20, July 2009 , pp. 2336-2348(13)

Publisher: Bentham Science Publishers

What is `early onset dementia'?

Author: MIYOSHI, Koho

Source: Psychogeriatrics, Volume 9, Number 2, June 2009 , pp. 67-72(6)

Publisher: Blackwell Publishing

Genetically Altering Aβ Distribution from the Brain to the Vasculature Ameliorates Tau Pathology

Authors: Oddo, Salvatore; Caccamo, Antonella; Cheng, David; LaFerla, Frank M.

Source: Brain Pathology, Volume 19, Number 3, July 2009 , pp. 421-430(10)

Publisher: Blackwell Publishing

Gene regulation as a potential avenue for the treatment of neurodegenerative disorders

Author: Brown, David R

Source: Expert Opinion on Drug Discovery, Volume 4, Number 5, May 2009 , pp. 515-524(10)

Publisher: Informa Healthcare

Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway

Authors: Takahashi, Keita; Niidome, Tetsuhiro; Akaike, Akinori; Kihara, Takeshi; Sugimoto, Hachiro

Source: Journal of Neurochemistry, Volume 109, Number 5, June 2009 , pp. 1324-1337(14)

Publisher: Blackwell Publishing

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

Authors: Guglielmotto, Michela; Aragno, Manuela; Autelli, Riccardo; Giliberto, Luca; Novo, Erica; Colombatto, Sebastiano; Danni, Oliviero; Parola, Maurizio; Smith, Mark A.; Perry, George; Tamagno, Elena; Tabaton, Massimo

Source: Journal of Neurochemistry, Volume 108, Number 4, February 2009 , pp. 1045-1056(12)

Publisher: Blackwell Publishing

Molecular genetics of Alzheimer's disease: An update

Authors: Brouwers, Nathalie; Sleegers, Kristel; Van Broeckhoven, Christine

Source: Annals of Medicine, Volume 40, Number 8, December 2008 , pp. 562-583(22)

Publisher: Informa Healthcare

Interview

Author: Goate, Alison

Source: Biomarkers in Medicine, Volume 2, Number 6, December 2008 , pp. 541-545(5)

Publisher: Future Medicine

Protein expression of BACE1, BACE2 and APP in Down syndrome brains

Authors: Cheon, M. S.; Dierssen, M.; Kim, S. H.; Lubec, G.

Source: Amino Acids, Volume 35, Number 2, August 2008 , pp. 339-343(5)

Publisher: Springer

A novel presenilin 2 mutation (V393M) in early-onset dementia with profound language impairment

Authors: Lindquist, S. G.; Hasholt, L.; Bahl, J. M. C.; Heegaard, N. H. H.; Andersen, B. B.; Nørremølle, A.; Stokholm, J.; Schwartz, M.; Batbayli, M.; Laursen, H.; Pardossi-Piquard, R.; Chen, F.; St George-Hyslop, P.; Waldemar, G.; Nielsen, J. E.

Source: European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1135-1139(5)

Publisher: Blackwell Publishing

Biomarkers for early diagnosis of Alzheimer disease: `ALZheimer ASsociated gene'- a new blood biomarker?

Authors: Jellinger, Kurt A.; Janetzky, Bernd; Attems, Johannes; Kienzl, Elisabeth

Source: Journal of Cellular and Molecular Medicine, Volume 12, Number 4, August 2008 , pp. 1094-1117(24)

Publisher: Blackwell Publishing

The Catalytic Core of γ-Secretase: Presenilin Revisited

Author: Steiner, Harald

Source: Current Alzheimer Research, Volume 5, Number 2, April 2008 , pp. 147-157(11)

Publisher: Bentham Science Publishers

Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

Authors: Cho, Hyun Jin; Jin, Seok Min; Youn, Hong Deuk; Huh, Kyoon; Mook-Jung, Inhee

Source: Aging Cell, Volume 7, Number 2, April 2008 , pp. 137-147(11)

Publisher: Blackwell Publishing

Functional Role of Lipoprotein Receptors in Alzheimer's Disease

Authors: Pietrzik, Claus U.; Jaeger, Sebastian

Source: Current Alzheimer Research, Volume 5, Number 1, February 2008 , pp. 15-25(11)

Publisher: Bentham Science Publishers

Pharmacogenetic Basis for Therapeutic Optimization in Alzheimer's Disease

Author: Cacabelos, Ramón

Source: Molecular Diagnosis & Therapy, Volume 11, Number 6, 2007 , pp. 385-405(21)

Publisher: Adis International

Is Alpha-Synuclein Pathology a Target for Treatment of Neurodegenerative Disorders?

Authors: Windisch, Manfred; Wolf, Hans-Jorg; Hutter-Paier, Birgit; Wronski, Robert

Source: Current Alzheimer Research, Volume 4, Number 5, December 2007 , pp. 556-561(6)

Publisher: Bentham Science Publishers

RNA Interference as a Tool for Alzheimer's Disease Therapy

Authors: Orlacchio, Antonio; Bernardi, Giorgio; Orlacchio, Aldo; Martino, Sabata

Source: Mini Reviews in Medicinal Chemistry, Volume 7, Number 11, November 2007 , pp. 1166-1176(11)

Publisher: Bentham Science Publishers