Search Results

α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation

Authors: Jäger, Sebastian; Leuchtenberger, Stefanie; Martin, Anne; Czirr, Eva; Wesselowski, Johanna; Dieckmann, Marco; Waldron, Elaine; Korth, Carsten; Koo, Edward H.; Heneka, Michael; Weggen, Sascha; Pietrzik, Claus U.

Source: Journal of Neurochemistry, Volume 111, Number 6, December 2009 , pp. 1369-1382(14)

Publisher: Blackwell Publishing

Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery

Authors: Cousins, Sarah L.; Hoey, Sarah E. A.; Anne Stephenson, F.; Perkinton, Michael S.

Source: Journal of Neurochemistry, Volume 111, Number 6, December 2009 , pp. 1501-1513(13)

Publisher: Blackwell Publishing

The structure and function of Alzheimer's gamma secretase enzyme complex

Authors: Krishnaswamy, Sudarsan; Verdile, Giuseppe; Groth, David; Kanyenda, Limbikani; Martins, Ralph N

Source: Critical Reviews in Clinical Laboratory Sciences, Volume 46, Numbers 5-6, December 2009 , pp. 282-301(20)

Publisher: Informa Healthcare

Suppression of APP-containing vesicle trafficking and production of β-amyloid by AID/DHHC-12 protein

Authors: Mizumaru, Chie; Saito, Yuhki; Ishikawa, Takao; Yoshida, Tomohiro; Yamamoto, Tohru; Nakaya, Tadashi; Suzuki, Toshiharu

Source: Journal of Neurochemistry, Volume 111, Number 5, December 2009 , pp. 1213-1224(12)

Publisher: Blackwell Publishing

Reduction of Aβ42 in brains of transgenic APPswemice by 2-3-chlorophenylaminophenylacetate

Authors: Cohen, Margo P; Shearman, Clyde W

Source: Clinical and Experimental Pharmacology and Physiology, Volume 36, Number 11, November 2009 , pp. 1099-1103(5)

Publisher: Blackwell Publishing

Metabolic stabilization of p53 by FE65 in the nuclear matrix of osmotically stressed cells

Authors: Nakaya, Tadashi; Kawai, Tomoko; Suzuki, Toshiharu

Source: FEBS Journal, Volume 276, Number 21, November 2009 , pp. 6364-6374(11)

Publisher: Blackwell Publishing

Unusual Death of a Transvestite: Identification of Crime Weapon and Survival Time

Authors: Cornetta, Sandra; Addante, Annalisa; Zotti, Fiorenza; Dell'Erba, Alessandro

Source: Journal of Forensic Sciences, Volume 54, Number 5, September 2009 , pp. 1149-1151(3)

Publisher: Blackwell Publishing

Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model

Authors: Choi, Jennifer H. K.; Berger, Jason D.; Mazzella, Matthew J.; Morales-Corraliza, Jose; Cataldo, Anne M.; Nixon, Ralph A.; Ginsberg, Stephen D.; Levy, Efrat; Mathews, Paul M.

Source: Journal of Neurochemistry, Volume 110, Number 6, September 2009 , pp. 1818-1827(10)

Publisher: Blackwell Publishing

The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

Author: Hardy, John

Source: Journal of Neurochemistry, Volume 110, Number 4, August 2009 , pp. 1129-1134(6)

Publisher: Blackwell Publishing

Disease-Modifying Approach to the Treatment of Alzheimer's Disease: From α-Secretase Activators to γ-Secretase Inhibitors and Modulators

Authors: Panza, Francesco; Solfrizzi, Vincenzo; Frisardi, Vincenza; Capurso, Cristiano; D'Introno, Alessia; Colacicco, Anna M.; Vendemiale, Gianluigi; Capurso, Antonio; Imbimbo, Bruno P.

Source: Drugs & Aging, Volume 26, Number 7, 1 July 2009 , pp. 537-555(19)

Publisher: Adis International

ADAM19/Adamalysin 19 Structure, Function, and Role as a Putative Target in Tumors and Inflammatory Diseases

Authors: Qi, Bin; Newcomer, Robert G.; Sang, Qing-Xiang A.

Source: Current Pharmaceutical Design, Volume 15, Number 20, July 2009 , pp. 2336-2348(13)

Publisher: Bentham Science Publishers

Astrocyte Networks and Epilepsy: When Stars Collide

Source: Epilepsy Currents, Volume 9, Number 4, July/August 2009 , pp. 113-115(3)

Publisher: Blackwell Publishing

Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-β secretion in vitro

Authors: Lv, J.; Jia, H.; Jiang, Y.; Ruan, Y.; Liu, Z.; Yue, W.; Beyreuther, K.; Tu, P.; Zhang, D.

Source: Acta Physiologica, Volume 196, Number 4, August 2009 , pp. 419-425(7)

Publisher: Blackwell Publishing

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

Authors: Kasher, Paul R.; De Vos, Kurt J.; Wharton, Stephen B.; Manser, Catherine; Bennett, Ellen J.; Bingley, Megan; Wood, Jonathan D.; Milner, Roy; McDermott, Christopher J.; Miller, Christopher C. J.; Shaw, Pamela J.; Grierson, Andrew J.

Source: Journal of Neurochemistry, Volume 110, Number 1, July 2009 , pp. 34-44(11)

Publisher: Blackwell Publishing

Mild cholesterol depletion reduces amyloid-β production by impairing APP trafficking to the cell surface

Authors: Guardia-Laguarta, Cristina; Coma, Mireia; Pera, Marta; Clarimón, Jordi; Sereno, Lidia; Agulló, José M.; Molina-Porcel, Laura; Gallardo, Eduard; Deng, Amy; Berezovska, Oksana; Hyman, Bradley T.; Blesa, Rafael; Gómez-Isla, Teresa; Lleó, Alberto

Source: Journal of Neurochemistry, Volume 110, Number 1, July 2009 , pp. 220-230(11)

Publisher: Blackwell Publishing

Genetically Altering Aβ Distribution from the Brain to the Vasculature Ameliorates Tau Pathology

Authors: Oddo, Salvatore; Caccamo, Antonella; Cheng, David; LaFerla, Frank M.

Source: Brain Pathology, Volume 19, Number 3, July 2009 , pp. 421-430(10)

Publisher: Blackwell Publishing

Progress in the Development of Nonpeptidomimetic BACE 1 Inhibitors for Alzheimer's Disease

Authors: Huang, Wen-Hai; Sheng, Rong; Hu, Yong-Zhou

Source: Current Medicinal Chemistry, Volume 16, Number 14, May 2009 , pp. 1806-1820(15)

Publisher: Bentham Science Publishers

Interleukin-1β enhances nucleotide-induced and α-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y₂ receptor

Authors: Kong, Qiongman; Peterson, Troy S.; Baker, Olga; Stanley, Emily; Camden, Jean; Seye, Cheikh I.; Erb, Laurie; Simonyi, Agnes; Wood, W. Gibson; Sun, Grace Y.; Weisman, Gary A.

Source: Journal of Neurochemistry, Volume 109, Number 5, June 2009 , pp. 1300-1310(11)

Publisher: Blackwell Publishing

Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway

Authors: Takahashi, Keita; Niidome, Tetsuhiro; Akaike, Akinori; Kihara, Takeshi; Sugimoto, Hachiro

Source: Journal of Neurochemistry, Volume 109, Number 5, June 2009 , pp. 1324-1337(14)

Publisher: Blackwell Publishing

Calsyntenins Mediate TGN Exit of APP in a Kinesin-1-Dependent Manner

Authors: Ludwig, Alexander; Blume, Jessica; Diep, Tu-My; Yuan, Ju; Mateos, José María; Leuthäuser, Kerstin; Steuble, Martin; Streit, Peter; Sonderegger, Peter

Source: Traffic, Volume 10, Number 5, May 2009 , pp. 572-589(18)

Publisher: Blackwell Publishing