Search Results

Molecular basis of thrombomodulin activation of slow thrombin

Authors: ADAMS, T. E.; LI, W.; HUNTINGTON, J. A.

Source: Journal of Thrombosis and Haemostasis, Volume 7, Number 10, October 2009 , pp. 1688-1695(8)

Publisher: Blackwell Publishing

Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa

Authors: Persson, Egon; Olsen, Ole H.

Source: FEBS Journal, Volume 276, Number 11, June 2009 , pp. 3099-3109(11)

Publisher: Blackwell Publishing

Turnover of ubiquinone-0 at the acceptor side of photosynthetic reaction center

Authors: Gerencsér, László; Maróti, Péter

Source: European Biophysics Journal, Volume 37, Number 7, September 2008 , pp. 1195-1205(11)

Publisher: Springer

The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity

Authors: Niemirowicz, Gabriela; Fernández, Daniel; Solà, Maria; Cazzulo, Juan J.; Avilés, Francesc X.; Gomis-Rüth, F. Xavier

Source: Molecular Microbiology, Volume 70, Number 4, November 2008 , pp. 853-866(14)

Publisher: Blackwell Publishing

Three-dimensional quantitative structure-activity relationship (CoMFA and CoMSIA) studies on galardin derivatives as gelatinase A (matrix metalloproteinase 2) inhibitors

Authors: Zheng, Jianbin; Wen, Ren; Guillaume, Dominique

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 23, Number 4, August 2008 , pp. 445-453(9)

Publisher: Informa Healthcare

Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo

Authors: NIEMAN, M. T.; BURKE, F.; WARNOCK, M.; ZHOU, Y.; SWEIGART, J.; CHEN, A.; RICKETTS, D.; LUCCHESI, B. R.; CHEN, Z.; DI CERA, E.; HILFINGER, J.; KIM, J. S.; MOSBERG, H. I.; SCHMAIER, A. H.

Source: Journal of Thrombosis and Haemostasis, Volume 6, Number 5, May 2008 , pp. 837-845(9)

Publisher: Blackwell Publishing

Role of Sulfonamide Group in Matrix Metalloproteinase Inhibitors

Authors: Cheng, Xian-Chao; Wang, Qiang; Fang, Hao; Xu, Wen-Fang

Source: Current Medicinal Chemistry, Volume 15, Number 4, February 2008 , pp. 368-373(6)

Publisher: Bentham Science Publishers

Thrombin inhibitors with novel P1 binding pocket functionality: free energy of binding analysis

Authors: Mlinsek, Gregor; Oblak, Marko; Hodoscek, Milan; Solmajer, Tom

Source: Journal of Molecular Modeling, Volume 13, Number 1, January 2007 , pp. 247-254(8)

Publisher: Springer

The molecular basis of urokinase inhibition: from the nonempirical analysis of intermolecular interactions to the prediction of binding affinity

Authors: Grzywa, Renata; Dyguda-Kazimierowicz, Edyta; Sieńczyk, Marcin; Feliks, Mikołaj; Sokalski, W.; Oleksyszyn, Józef

Source: Journal of Molecular Modeling, Volume 13, Numbers 6-7, July 2007 , pp. 677-683(7)

Publisher: Springer

Editorial [Hot Topic: Rational Drug Design (Executive Editor: M. Rami Reddy)]

Author: Reddy, M. R.

Source: Current Pharmaceutical Design, Volume 13, Number 34, December 2007 , pp. 3453-3453(1)

Publisher: Bentham Science Publishers

Molecular Dynamics Simulations of Metalloproteinases Types 2 and 3 Reveal Differences in the Dynamic Behavior of the S1' Binding Pocket

Authors: de Oliveira, Cesar Augusto F.; Zissen, Maurice; Mongon, John; Mccammon, J. A.

Source: Current Pharmaceutical Design, Volume 13, Number 34, December 2007 , pp. 3471-3475(5)

Publisher: Bentham Science Publishers

Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis

Authors: Mlčochová, Petra; Plechanovová, Anna; Bařinka, Cyril; Mahadevan, Daruka; Saldanha, Jose W.; Rulíšek, Lubomír; Konvalinka, Jan

Source: FEBS Journal, Volume 274, Number 18, September 2007 , pp. 4731-4741(11)

Publisher: Blackwell Publishing

Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding

Authors: Perazzolo, Chiara; Verde, Mariachiara; Homans, Steve; Bodenhausen, Geoffrey

Source: Journal of Biomolecular NMR, Volume 38, Number 1, May 2007 , pp. 3-9(7)

Publisher: Springer

Molecular Recognition of Ligands in Dipeptidyl Peptidase IV

Authors: Kuhn, Bernd; Hennig, Michael; Mattei, Patrizio

Source: Current Topics in Medicinal Chemistry, Volume 7, Number 6, March 2007 , pp. 609-620(12)

Publisher: Bentham Science Publishers

Crystal structure of the β-chain of human hepatocyte growth factor-like/macrophage stimulating protein

Authors: Carafoli, Federico; Chirgadze, Dimitri Y.; Blundell, Tom L.; Gherardi, Ermanno

Source: FEBS Journal, Volume 272, Number 22, November 2005 , pp. 5799-5807(9)

Publisher: Blackwell Publishing

Matrix Metalloproteinase Inhibitors: A Review on Pharmacophore Mapping and (Q)Sars Results

Authors: C. A. Kontogiorgis; P. Papaioannou; D. J. Hadjipavlou-Litina

Source: Current Medicinal Chemistry, Volume 12, Number 3, February 2005 , pp. 339-355(17)

Publisher: Bentham Science Publishers

Structure-based design of inhibitors of NS3 serine protease of hepatitis C virus

Authors: Frecer V.; Kabelac M.; De Nardi P.; Pricl S.; Miertus S.

Source: Journal of Molecular Graphics and Modelling, Volume 22, Number 3, January 2004 , pp. 209-220(12)

Publisher: Elsevier

Modeling of enzyme–substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10

Authors: Manzetti S.; McCulloch D.R.; Herington A.C.; van der Spoel D.

Source: Journal of Computer-Aided Molecular Design, Volume 17, Number 9, September 2003 , pp. 551-565(15)

Publisher: Springer

Structural Consequences of Accommodation of Four Non-cognate Amino Acid Residues in the S1 Pocket of Bovine Trypsin and Chymotrypsin

Authors: Helland R.; Czapinska H.; Leiros I.; Olufsen M.; Otlewski J.; Smalas A.O.

Source: Journal of Molecular Biology, Volume 333, Number 4, 31 October 2003 , pp. 845-861(17)

Publisher: Elsevier

Efficient Conformational Sampling of Local Side-chain Flexibility

Authors: Kallblad P.; Dean P.M.

Source: Journal of Molecular Biology, Volume 326, Number 5, 7 March 2003 , pp. 1651-1665(15)

Publisher: Elsevier