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Protective mechanisms of activated protein C in severe inflammatory disorders

Authors: Neyrinck, Arne P; Liu, Kathleen D; Howard, James P; Matthay, Michael A

Source: British Journal of Pharmacology, Volume 158, Number 4, October 2009 , pp. 1034-1047(14)

Publisher: Blackwell Publishing

α-Fetoprotein as a modulator of the pro-inflammatory response of human keratinocytes

Authors: Potapovich, AI; Pastore, S; Kostyuk, VA; Lulli, D; Mariani, V; De Luca, C; Dudich, EI; Korkina, LG

Source: British Journal of Pharmacology, Volume 158, Number 5, November 2009 , pp. 1236-1247(12)

Publisher: Blackwell Publishing

Evaluation of anti-activated protein C antibody development in patients with severe sepsis from four clinical studies with drotrecogin alfa (activated)

Authors: YAN, S. B.; BRANDT, J. T.; CORRELL, N. L.; UM, S. L.; BOURDAGE, J. S.

Source: Journal of Thrombosis and Haemostasis, Volume 7, Number 11, November 2009 , pp. 1787-1794(8)

Publisher: Blackwell Publishing

Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma

Authors: Krisinger, Michael J.; Guo, Li Jun; Salvagno, Gian Luca; Guidi, Gian Cesare; Lippi, Giuseppe; Dahlbäck, Björn

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6586-6602(17)

Publisher: Blackwell Publishing

Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1

Authors: Gupta, Akanksha; Williams, Mark D.; Macias, William L.; Molitoris, Bruce A.; Grinnell, Brian W.

Source: Current Drug Targets, Volume 10, Number 12, December 2009 , pp. 1212-1226(15)

Publisher: Bentham Science Publishers

Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor α agonist in preclinical species and human

Authors: Frederick, K.S.; Maurer, T.S.; Kalgutkar, A.S.; Royer, L.J.; Francone, O.L.; Winter, S.M.; Terra, S.G.; Chen, D.; Gao, X.

Source: Xenobiotica, Volume 39, Number 10, October 2009 , pp. 766-781(16)

Publisher: Informa Healthcare

5-HT_1A receptors are involved in the effects of xaliproden on G-protein activation, neurotransmitter release and nociception

Authors: Martel, J-C; Assié, M-B; Bardin, L; Depoortère, R; Cussac, D; Newman-Tancredi, A

Source: British Journal of Pharmacology, Volume 158, Number 1, September 2009 , pp. 232-242(11)

Publisher: Blackwell Publishing

High molecular weight kininogen binds to laminin - characterization and kinetic analysis

Authors: Schousboe, Inger; Nystrøm, Birthe

Source: FEBS Journal, Volume 276, Number 18, September 2009 , pp. 5228-5238(11)

Publisher: Blackwell Publishing

Coagulation Disorders in Acute Lung Injury

Authors: Adda, Melanie; Ferrer, Ricard; Puig, Ferranda; Crespo, Javier; Artigas, Antoni

Source: Current Respiratory Medicine Reviews, Volume 5, Number 3, August 2009 , pp. 149-159(11)

Publisher: Bentham Science Publishers

Tirofiban and Activated Protein C Synergistically Inhibit the Instant Blood Mediated Inflammatory Reaction (IBMIR) from Allogeneic Islet Cells Exposure to Human Blood

Authors: Akima, S.; Hawthorne, W. J.; Favaloro, E.; Patel, A.; Blyth, K.; Mudaliar, Y.; Chapman, J. R.; O'Connell, P. J.

Source: American Journal of Transplantation, Volume 9, Number 7, July 2009 , pp. 1533-1540(8)

Publisher: Blackwell Publishing

Activation of latent transforming growth factor-β1 by nitric oxide in macrophages: Role of soluble guanylate cyclase and MAP kinases

Authors: Metukuri, Mallikarjuna Reddy; Namas, Rajaie; Gladstone, Chase; Clermont, Thierry; Jefferson, Bahiyya; Barclay, Derek; Hermus, Linda; Billiar, Timothy R.; Zamora, Ruben; Vodovotz, Yoram

Source: Wound Repair and Regeneration, Volume 17, Number 4, July/August 2009 , pp. 578-588(11)

Publisher: Blackwell Publishing

Thioredoxin reduces C-C chemokine-induced chemotaxis of human eosinophils

Authors: Kobayashi, N.; Yamada, Y.; Ito, W.; Ueki, S.; Kayaba, H.; Nakamura, H.; Yodoi, J.; Chihara, J.

Source: Allergy, Volume 64, Number 8, August 2009 , pp. 1130-1135(6)

Publisher: Blackwell Publishing

The non-proteolytic house dust mite allergen Der p 2 induce NF-κB and MAPK dependent activation of bronchial epithelial cells

Authors: Österlund, C.; Grönlund, H.; Polovic, N.; Sundström, S.; Gafvelin, G.; Bucht, A.

Source: Clinical & Experimental Allergy, Volume 39, Number 8, August 2009 , pp. 1199-1208(10)

Publisher: Blackwell Publishing

Insulin-Like Growth Factor-I Deficiency in Children with Growth Hormone Insensitivity: Current and Future Treatment Options

Author: Kemp, Stephen F.

Source: BioDrugs, Volume 23, Number 3, 3 June 2009 , pp. 155-163(9)

Publisher: Adis International

Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli

Authors: Bae, M.-Y.; Cho, N.-H.; Seong, S.-Y.

Source: Clinical & Experimental Immunology, Volume 157, Number 1, July 2009 , pp. 128-138(11)

Publisher: Blackwell Publishing

Expression Pattern, Ethanol-Metabolizing Activities, and Cellular Localization of Alcohol and Aldehyde Dehydrogenases in Human Pancreas: Implications for Pathogenesis of Alcohol-Induced Pancreatic Injury

Authors: Chiang, Chien-Ping; Wu, Chew-Wun; Lee, Shiao-Pieng; Chung, Chia-Chi; Wang, Chi-Wei; Lee, Shou-Lun; Nieh, Shin; Yin, Shih-Jiun

Source: Alcoholism Clinical and Experimental Research, Volume 33, Number 6, June 2009 , pp. 1059-1068(10)

Publisher: Blackwell Publishing

The use of drotrecogin alfa (activated) in solid organ transplant patients: a case series

Authors: Berkman, S.; Weimert, N.A.; Taber, D.J.; Baillie, G.M.; Lin, A.; Baliga, P.; Chavin, K.D.

Source: Transplant Infectious Disease, Volume 11, Number 3, June 2009 , pp. 269-276(8)

Publisher: Blackwell Publishing

T cells and eosinophils in bronchial smooth muscle cell death in asthma

Authors: Solarewicz-Madejek, K.; Basinski, T. M.; Crameri, R.; Akdis, M.; Akkaya, A.; Blaser, K.; Rabe, K. F.; Akdis, C. A.; Jutel, M.

Source: Clinical & Experimental Allergy, Volume 39, Number 6, June 2009 , pp. 845-855(11)

Publisher: Blackwell Publishing

Activated protein C for the treatment of severe sepsis

Authors: Houston, G.; Cuthbertson, B. H.

Source: Clinical Microbiology & Infection, Volume 15, Number 4, April 2009 , pp. 319-324(6)

Publisher: Blackwell Publishing

Recombinant Human Erythropoietin Protects Against Experimental Spinal Cord Trauma Injury by Regulating Expression of the Proteins MKP-1 and p-ERK

Authors: Huang, H.; Fan, S.; Ji, X.; Zhang, Y.; Bao, F.; Zhang, G.

Source: The Journal of International Medical Research, Volume 37, Number 2, March 2009 , pp. 511-519(9)

Publisher: Field House Publishing