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Optimizing Sustained Use of Sedation in Mechanically Ventilated Patients: Focus on Safety

Authors: Arnold, Heather M.; Hollands, James M.; Skrupky, Lee P.; Micek, Scott T.

Source: Current Drug Safety, Volume 5, Number 1, January 2010 , pp. 6-12(7)

Publisher: Bentham Science Publishers

The Role of Pemetrexed in Advanced Non Small-Cell Lung Cancer: Special Focus on Pharmacology and Mechanism of Action

Authors: Joerger, M.; Omlin, A.; Cerny, T.; Fruh, M.

Source: Current Drug Targets, Volume 11, Number 1, January 2010 , pp. 37-47(11)

Publisher: Bentham Science Publishers

Predictive Markers for Haematological Toxicity of Pemetrexed

Authors: Kao, S. C.H.; Phan, V. H.; Clarke, S. J.

Source: Current Drug Targets, Volume 11, Number 1, January 2010 , pp. 48-57(10)

Publisher: Bentham Science Publishers

Effects of Velusetrag (TD-5108) on gastrointestinal transit and bowel function in health and pharmacokinetics in health and constipation

Authors: manini, m. l.; camilleri, m.; goldberg, m.; sweetser, s.; mckinzie, s.; burton, d.; wong, s.; kitt, m. m.; li, y.-p.; zinsmeister, a. r.

Source: Neurogastroenterology and Motility, Volume 22, Number 1, January 2010 , pp. 42-e8(-41)

Publisher: Blackwell Publishing

Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice

Authors: Käenmäki, M; Tammimäki, A; Garcia-Horsman, JA; Myöhänen, T; Schendzielorz, N; Karayiorgou, M; Gogos, JA; Männistö, PT

Source: British Journal of Pharmacology, Volume 158, Number 8, December 2009 , pp. 1884-1894(11)

Publisher: Blackwell Publishing

Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1

Authors: Dreiseitel, A; Oosterhuis, B; Vukman, KV; Schreier, P; Oehme, A; Locher, S; Hajak, G; Sand, PG

Source: British Journal of Pharmacology, Volume 158, Number 8, December 2009 , pp. 1942-1950(9)

Publisher: Blackwell Publishing

Pharmacokinetics and pharmacodynamics of a new reformulated microemulsion and the long-chain triglyceride emulsion of propofol in beagle dogs

Authors: Lee, S-H; Ghim, J-L; Song, M-H; Choi, H-G; Choi, B-M; Lee, H-M; Lee, E-K; Roh, Y-J; Noh, G-J

Source: British Journal of Pharmacology, Volume 158, Number 8, December 2009 , pp. 1982-1995(14)

Publisher: Blackwell Publishing

Mercury exposure with thiomersal vax shows little risk in newborns

Source: Reactions, Volume 1, Number 1279, 2009-11-21 , pp. 4-4(1)

Publisher: Adis International

Altered expression of CYP in TSOD mice: a model of type 2 diabetes and obesity

Authors: Kudo, T.; Shimada, T.; Toda, T.; Igeta, S.; Suzuki, W.; Ikarashi, N.; Ochiai, W.; Ito, K.; Aburada, M.; Sugiyama, K.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 889-902(14)

Publisher: Informa Healthcare

Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage

Authors: Miura, M.; Inoue, K.; Kagaya, H.; Saito, M.; Habuchi, T.; Satoh, S.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 939-945(7)

Publisher: Informa Healthcare

Effects of Escherichia coli lipopolysaccharide on the metformin pharmacokinetics in rats

Authors: Cho, Y. K.; Choi, Y. H.; Kim, S. H.; Lee, M. G.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 946-954(9)

Publisher: Informa Healthcare

Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism

Authors: Chen, L.; Yang, J.; Davey, A. K.; Chen, Y.-X.; Wang, J.-P.; Liu, X.-Q.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 955-963(9)

Publisher: Informa Healthcare

Cross-species comparisons of the pharmacokinetics of ibudilast

Authors: Sanftner, L. M.; Gibbons, J. A.; Gross, M. I.; Suzuki, B. M.; Gaeta, F. C. A.; Johnson, K. W.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 964-977(14)

Publisher: Informa Healthcare

Preparation, characterization, and pharmacokinetics of the inclusion complex of genipin-β-cyclodextrin

Authors: Lu, Yi; Zhang, Tong; Tao, Jiansheng; Ji, Guang; Wang, Shaomin

Source: Drug Development and Industrial Pharmacy, Volume 35, Number 12, December 2009 , pp. 1452-1459(8)

Publisher: Informa Healthcare

Formulation design and pharmaceutical development of a novel controlled release form of azithromycin for single-dose therapy

Authors: Lo, Julian B.; Appel, Leah E.; Herbig, Scott M.; McCray, Scott B.; Thombre, Avinash G.

Source: Drug Development and Industrial Pharmacy, Volume 35, Number 12, December 2009 , pp. 1522-1529(8)

Publisher: Informa Healthcare

Determination of Phenytoin and its Major Metabolite in Human Serum by MEKC

Authors: Jabbaribar, F.; Mortazavi, S.A.; Jouyban, A.

Source: Journal of Chromatographic Science, Volume 47, Number 10, November/December 2009 , pp. 877-880(4)

Publisher: Preston Publications

Determination of Adefovir by LC-ESI-MS-MS and Its Application to a Pharmacokinetic Study in Healthy Chinese Volunteers

Authors: Zou, Jianjun; Di, Bin; Zhang, Junren; Dai, Li; Ding, Li; Zhu, Yubing; Fan, Hongwei; Xiao, DaWei

Source: Journal of Chromatographic Science, Volume 47, Number 10, November/December 2009 , pp. 889-894(6)

Publisher: Preston Publications

Pharmacokinetics and safety of fibrinogen concentrate

Authors: MANCO-JOHNSON, M. J.; DIMICHELE, D.; CASTAMAN, G.; FREMANN, S.; KNAUB, S.; KALINA, U.; PEYVANDI, F.; PISEDDU, G.; MANNUCCI, P.

Source: Journal of Thrombosis and Haemostasis, Volume 7, Number 12, December 2009 , pp. 2064-2069(6)

Publisher: Blackwell Publishing

Heterogeneity of tumour response to combined radiotherapy and EGFR inhibitors: Differences between antibodies and TK inhibitors

Authors: Krause, Mechthild; Gurtner, Kristin; Deuse, Yvonne; Baumann, Michael

Source: International Journal of Radiation Biology, Volume 85, Number 11, November 2009 , pp. 943-954(12)

Publisher: Informa Healthcare

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers

Authors: Lim, Kyoung Soo; Cho, Joo-Youn; Kim, Bo-Hyung; Kim, Jung-Ryul; Kim, Hwa-Sook; Kim, Dong-Kyu; Kim, Sung-Ho; Yim, Hyeon Joo; Lee, Sung-Hack; Shin, Sang-Goo; Jang, In-Jin; Yu, Kyung-Sang

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 883-890(8)

Publisher: Blackwell Publishing