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Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Authors: Roberts, Jason A.; Kirkpatrick, Carl M. J.; Roberts, Michael S.; Robertson, Thomas A.; Dalley, Andrew J.; Lipman, Jeffrey

Source: Journal of Antimicrobial Chemotherapy, Volume 64, Number 1, 14 July 2009 , pp. 142-150(9)

Publisher: Oxford University Press

Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats

Authors: Scholz, M.; Engel, C.; Apt, D.; Sankar, S. L.; Goldstein, E.; Loeffler, M.

Source: Cell Proliferation, Volume 42, Number 6, December 2009 , pp. 823-837(15)

Publisher: Blackwell Publishing

Retrospective population pharmacokinetic/pharmacodynamic analysis of pyridostigmine, a cholinesterase inhibitor, in Chinese males

Authors: Seng, Kok-Yong; Loke, Weng-Keong; Moochhala, Shabbir; Zhao, Bin; Lee, Jon-Deoon Edmund

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 9, September 2009 , pp. 1187-1196(10)

Publisher: Pharmaceutical Press

Pharmacokinetic-Pharmacodynamic Modelling of the Antihistaminic (H₁) Effect of Bilastine

Authors: Jauregizar, Nerea; >Leire de la Fuente,; >Maria Luisa Lucero,; Sologuren, Ander; Leal, Nerea; Rodríguez, Mónica

Source: Clinical Pharmacokinetics, Volume 48, Number 8, 1 August 2009 , pp. 543-554(12)

Publisher: Adis International

Morphine Glucuronidation in Preterm Neonates, Infants and Children Younger than 3 Years

Authors: Knibbe, Catherijne A.J.; Krekels, Elke H.J.; >Johannes N. van den Anker,; DeJongh, Joost; Santen, Gijs W.E.; >Monique van Dijk,; Simons, Sinno H.P.; van Lingen, Richard A.; Jacqz-Aigrain, Evelyne M.; Danhof, Meindert; Tibboel, Dick

Source: Clinical Pharmacokinetics, Volume 48, Number 6, 6 June 2009 , pp. 371-385(15)

Publisher: Adis International

From pharmacokinetics to therapeutics

Authors: Church, Martin K.; Gillard, Michel; Sargentini-Maier, Maria Laura; Poggesi, Italo; Campbell, Alison; Benedetti, Margherita Strolin

Source: Drug Metabolism Reviews, Volume 41, Number 3, August 2009 , pp. 455-474(20)

Publisher: Informa Healthcare

Population pharmacokinetic and pharmacodynamic analysis in allergic diseases

Authors: Lovern, Mark; Sargentini-Maier, Maria-Laura; Otoul, Christian; Watelet, Jean-Baptiste

Source: Drug Metabolism Reviews, Volume 41, Number 3, August 2009 , pp. 475-485(11)

Publisher: Informa Healthcare

Increased sensitivity to diltiazem hypotensive effect in an experimental model of high-renin hypertension

Authors: Bertera, Facundo M.; Mayer, Marcos A.; Opezzo, Javier A.W.; Taira, Carlos A.; Höcht, Christian

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 1, January 2009 , pp. 79-87(9)

Publisher: Pharmaceutical Press

Pharmacokinetics and pharmacodynamics of antimicrobial drugs

Authors: Czock, David; Markert, Christoph; Hartman, Bertram; Keller, Frieder

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 5, May 2009 , pp. 475-487(13)

Publisher: Informa Healthcare

Measurement and prediction of the rate and extent of drug delivery into and through the skin

Authors: Russell, LM; Guy, RH

Source: Expert Opinion on Drug Delivery, Volume 6, Number 4, April 2009 , pp. 355-369(15)

Publisher: Informa Healthcare

Modelling of α₁-adrenoceptor-mediated temporal dynamics of inotropic response in rat heart to assess ligand binding and signal transduction parameters

Authors: Sermsappasuk, P; Weiss, M

Source: British Journal of Pharmacology, Volume 156, Number 5, March 2009 , pp. 764-773(10)

Publisher: Blackwell Publishing

Use of pharmacokinetic/ pharmacodynamic modelling for starting dose selection in first-in-human trials of high-risk biologics

Author: Agoram, Balaji M.

Source: British Journal of Clinical Pharmacology, Volume 67, Number 2, February 2009 , pp. 153-160(8)

Publisher: Blackwell Publishing

Use of a pharmacokinetic/pharmacodynamic approach in the cat to determine a dosage regimen for the COX-2 selective drug robenacoxib

Authors: GIRAUDEL, J. M.; KING, J. N.; JEUNESSE, E. C.; LEES, P.; TOUTAIN, P.-L.

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 32, Number 1, February 2009 , pp. 18-30(13)

Publisher: Blackwell Publishing

Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib

Authors: GIRAUDEL, J. M; TOUTAIN, P.-L.; KING, J. N.; LEES, P.

Source: Journal of Veterinary Pharmacology & Therapeutics, Volume 32, Number 1, February 2009 , pp. 31-40(10)

Publisher: Blackwell Publishing

Development of an integrated semi-automated system for in vitro pharmacodynamic modelling

Authors: Wang, Liangsu; Wismer, Michael K.; Racine, Fred; Conway, Donald; Giacobbe, Robert A.; Berejnaia, Olga; Kath, Gary S.

Source: Journal of Antimicrobial Chemotherapy, Volume 62, Number 5, 30 November 2008 , pp. 1070-1077(8)

Publisher: Oxford University Press

Sample Size Calculations for Population Pharmacodynamic Experiments Involving Repeated Dichotomous Observations

Authors: Ogungbenro, Kayode; Aarons, Leon

Source: Journal of Biopharmaceutical Statistics, Volume 18, Number 6, November 2008 , pp. 1212-1227(16)

Publisher: Taylor and Francis Ltd

Hydroxyzine and cetirizine pharmacokinetics and pharmacodynamics after oral and intravenous administration of hydroxyzine to healthy dogs

Authors: Bizikova, Petra; Papich, Mark G.; Olivry, Thierry

Source: Veterinary Dermatology, Volume 19, Number 6, December 2008 , pp. 348-357(10)

Publisher: Blackwell Publishing

A comparative study of two methods for attaining constant alcohol levels

Authors: Zoethout, Remco W. M.; van Gerven, Joop M. A.; Dumont, Glenn J. H.; Paltansing, Sunita; van Burgel, Nathalie D.; van der Linden, Monique; Dahan, Albert; Cohen, Adam F.; Schoemaker, Rik C.

Source: British Journal of Clinical Pharmacology, Volume 66, Number 5, November 2008 , pp. 674-681(8)

Publisher: Blackwell Publishing

Pharmacokinetic/Pharmacodynamic Modelling of Venlafaxine: Pupillary Light Reflex as a Test System for Noradrenergic Effects

Authors: Lindauer, Andreas; Siepmann, Timo; Oertel, Reinhard; Jung, Angelika; Ziemssen, Tjalf; Jaehde, Ulrich; Kirch, Wilhelm; Siepmann, Martin

Source: Clinical Pharmacokinetics, Volume 47, Number 11, 2008 , pp. 721-731(11)

Publisher: Adis International

Population pharmacokinetic and pharmacodynamic analysis to support treatment optimization of combination chemotherapy with indisulam and carboplatin

Authors: Zandvliet, Anthe S.; Schellens, Jan H. M.; Dittrich, Christian; Wanders, Jantien; Beijnen, Jos H.; Huitema, Alwin D. R.

Source: British Journal of Clinical Pharmacology, Volume 66, Number 4, October 2008 , pp. 485-497(13)

Publisher: Blackwell Publishing