Search Results

Targeting the Peptide Deformylase of Mycobacterium tuberculosis Leads to Drug Discovery

Authors: Singh, Vijai; Somvanshi, Pallavi

Source: Letters in Drug Design & Discovery, Volume 6, Number 7, October 2009 , pp. 487-493(7)

Publisher: Bentham Science Publishers

Peptide deformylase - a promising therapeutic target for tuberculosis and antibacterial drug discovery

Authors: Sharma, Anshika; Khuller, Gopal K; Sharma, Sadhna

Source: Expert Opinion on Therapeutic Targets, Volume 13, Number 7, July 2009 , pp. 753-765(13)

Publisher: Informa Healthcare

Synthesis and In Vitro Antibacterial Activity of (2S)-N-(Substitutedphenyl)-1-[(2R)-2-[(Formylhydroxyamino)Methyl]-1-Oxohexyl]-2-Pyrrolidinecarboxamides as Potential Peptide Deformylase Inhibitors

Authors: Wang, Zhenyu; Zhou, Weicheng

Source: Chemical Biology & Drug Design, Volume 73, Number 1, January 2009 , pp. 142-146(5)

Publisher: Blackwell Publishing

The Use of Structure-Guided Design to Discover New Anti-Microbial Agents: Focus on Antibacterial Resistance

Authors: Charifson, P. S.; Grossman, T. H.; Mueller, P.

Source: Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Infective Agents), Volume 8, Number 1, January 2009 , pp. 73-86(14)

Publisher: Bentham Science Publishers

Targeting Bacterial Metalloenzymes: A New Strategy for the Development of Anti-Infective Agents

Authors: Winum, Jean-Yves; Kohler, Stephan; Scozzafava, Andrea; Montero, Jean-Louis; Supuran, Claudiu T.

Source: Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Infective Agents), Volume 7, Number 3, July 2008 , pp. 169-179(11)

Publisher: Bentham Science Publishers

The Plastid-Like Organelle of Apicomplexan Parasites as Drug Target

Authors: Wiesner, J.; Reichenberg, A.; Heinrich, S.; Schlitzer, M.; Jomaa, H.

Source: Current Pharmaceutical Design, Volume 14, Number 9, March 2008 , pp. 855-871(17)

Publisher: Bentham Science Publishers

Comparative QSAR studies on peptide deformylase inhibitors

Authors: Lee, Ji; Doddareddy, Munikumar; Cho, Yong; Choo, Hyunah; Koh, Hun; Kang, Jae-Hoon; No, Kyoung; Pae, Ae

Source: Journal of Molecular Modeling, Volume 13, Number 5, May 2007 , pp. 543-558(16)

Publisher: Springer

Plant peptide deformylase: a novel selectable marker and herbicide target based on essential cotranslational chloroplast protein processing

Authors: Hou, Cai-Xia; Dirk, Lynnette M. A.; Pattanaik, Sitakanta; Das, Narayan C.; Maiti, Indu B.; Houtz, Robert L.; Williams, Mark A.

Source: Plant Biotechnology Journal, Volume 5, Number 2, March 2007 , pp. 275-281(7)

Publisher: Blackwell Publishing

Investigational treatments for postoperative surgical site infections

Authors: Poulakou, Garyphallia; Giamarellou, Helen

Source: Expert Opinion on Investigational Drugs, Volume 16, Number 2, February 2007 , pp. 137-155(19)

Publisher: Informa Healthcare

Peptide deformylase inhibitors: a survey of the patent literature

Authors: Molteni, Valentina; Kreusch, Andreas

Source: Expert Opinion on Therapeutic Patents, Volume 15, Number 10, 1 October 2005 , pp. 1423-1437(15)

Publisher: Informa Healthcare

Therapeutic potential of peptide deformylase inhibitors

Authors: Chen, D; Yuan, Z

Source: Expert Opinion on Investigational Drugs, Volume 14, Number 9, 1 September 2005 , pp. 1107-1116(10)

Publisher: Informa Healthcare

Bacterial Peptide Deformylase Inhibitors: A New Class of Antibacterial Agents

Authors: Jain, R.; Chen, D.; White, R. J.; Patel, D. V.; Yuan, Z.

Source: Current Medicinal Chemistry, Volume 12, Number 14, July 2005 , pp. 1607-1621(15)

Publisher: Bentham Science Publishers

PDF Inhibitors: An Emerging Class of Antibacterial Drugs

Authors: K. W. Johnson; D. Lofland; H. E. Moser

Source: Current Drug Targets - Infectious Disorders, Volume 5, Number 1, March 2005 , pp. 39-52(14)

Publisher: Bentham Science Publishers

Protein N-terminal methionine excision

Authors: Giglione, C.; Boularot, A.; Meinnel, T.

Source: Cellular and Molecular Life Sciences CMLS, Volume 61, Number 12, June 2004 , pp. 1455-1474(20)

Publisher: Springer

Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates

Authors: Ronald N. Jones; Gary J. Moet; Helio S. Sader; Thomas R. Fritsche

Source: Journal of Antimicrobial Chemotherapy, Volume 53, Number 5, May 2004 , pp. 804-807(4)

Publisher: Oxford University Press

Superbugs & Superdrugs: A Focus on Antibacterials – 6th Annual SMi Conference

Author: Georgopapadakou N.

Source: Expert Opinion on Emerging Drugs, Volume 9, Number 1, 1 May 2004 , pp. 191-195(5)

Publisher: Informa Healthcare

BB-3497, a peptide deformylase inhibitor, is active against Mycobacterium tuberculosis

Authors: Michael H. Cynamon; Enriques Alvirez-Freites; Anthony E. T. Yeo

Source: Journal of Antimicrobial Chemotherapy, Volume 53, Number 2, February 2004 , pp. 403-405(3)

Publisher: Oxford University Press

Peptide deformylase inhibitors with activity against respiratory tract pathogens

Authors: East S.P.; Beckett R.P.; Brookings D.C.; Clements J.M.; Doel S.; Keavey K.; Pain G.; Smith H.K.; Thomas W.; Thompson A.J.; Todd R.S.; Whittaker M.

Source: Bioorganic and Medicinal Chemistry Letters, Volume 14, Number 1, 5 January 2004 , pp. 59-62(4)

Publisher: Elsevier

Antibiotic resistance in Staphylococcus aureus: concerns, causes and cures

Author: Chopra, Ian

Source: Expert Review of Anti-Infective Therapy, Volume 1, Number 1, June 2003 , pp. 45-55(11)

Publisher: Expert Reviews

In vitro activities of nine peptide deformylase inhibitors and five comparator agents against respiratory and skin pathogens

Authors: Bowker K.E.; Noel A.R.; MacGowan A.P.

Source: International Journal of Antimicrobial Agents, Volume 22, Number 6, December 2003 , pp. 557-561(5)

Publisher: Elsevier