Search Results

Population pharmacokinetic and pharmacodynamic analysis in allergic diseases

Authors: Lovern, Mark; Sargentini-Maier, Maria-Laura; Otoul, Christian; Watelet, Jean-Baptiste

Source: Drug Metabolism Reviews, Volume 41, Number 3, August 2009 , pp. 475-485(11)

Publisher: Informa Healthcare

Pharmacokinetic-Pharmacodynamic Modeling of Antihypertensive Drugs: From Basic Research to Clinical Practice

Authors: Hocht, Christian; Mayer, Marcos A.; Opezzo, Javier A.W.; Bertera, Facundo M.; Taira, Carlos A.

Source: Current Hypertension Reviews, Volume 4, Number 4, November 2008 , pp. 289-302(14)

Publisher: Bentham Science Publishers

Pharmacokinetic/pharmacodynamic modeling of cardiac toxicity in human acute overdoses: utility and limitations

Authors: Mégarbane, Bruno; Aslani, Arsia Amir; Deye, Nicolas; Baud, Frédéric J

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 4, Number 5, May 2008 , pp. 569-579(11)

Publisher: Informa Healthcare

Population pharmacokinetic and pharmacodynamic modeling of norvancomycin

Authors: Zhang, J.; Zhang, Y.; Shi, Y.; Rui, J.; Yu, J.; Cao, G.; Wu, J.

Source: European Journal of Clinical Microbiology and Infectious Diseases, Volume 27, Number 4, April 2008 , pp. 275-284(10)

Publisher: Springer

Applications of Computer-Aided Pharmacokinetic and Pharmacodynamic Methods from Drug Discovery Through Registration

Authors: Dong, Jennifer Q.; Chen, Bin; Gibbs, Megan A.; Emery, Maurice; Gibbs, John P.

Source: Current Computer - Aided Drug Design, Volume 4, Number 1, March 2008 , pp. 54-66(13)

Publisher: Bentham Science Publishers

A Pharmacokinetic/Pharmacodynamic Approach to Predict Total Prednisolone Concentrations in Human Plasma

Authors: Xu, J.; Winkler, J.; Derendorf, H.

Source: Journal of Pharmacokinetics and Pharmacodynamics, Volume 34, Number 3, June 2007 , pp. 355-372(18)

Publisher: Springer

Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents - minimum inhibitory concentration versus time-kill curves

Authors: Schmidt, Stephan; Schuck, Edgar; Kumar, Vipul; Burkhardt, Olaf; Derendorf, Hartmut

Source: Expert Opinion on Drug Discovery, Volume 2, Number 6, June 2007 , pp. 849-860(12)

Publisher: Informa Healthcare

Population Pharmacokinetic/Pharmacodynamic Modeling of Systemic Corticosteroid Inhibition of Whole Blood Lymphocytes: Modeling Interoccasion Pharmacodynamic Variability

Authors: Hong, Ying; Mager, Donald; Blum, Robert; Jusko, William

Source: Pharmaceutical Research, Volume 24, Number 6, June 2007 , pp. 1088-1097(10)

Publisher: Springer

Sevoflurane increases fade of neuromuscular response to TOF stimulation following rocuronium administration in children. A PK/PD analysis

Authors: WOLOSZCZUK-GEBICKA, BOGUMILA; WYSKA, ELŻBIETA; GRABOWSKI, TOMASZ

Source: Paediatric Anaesthesia, Volume 17, Number 7, July 2007 , pp. 637-646(10)

Publisher: Blackwell Publishing

Mixture Modeling for the Detection of Subpopulations in a Pharmacokinetic/Pharmacodynamic analysis

Authors: Lemenuel-diot, Annabelle; Laveille, Christian; Frey, Nicolas; Jochemsen, Roeline; Mallet, Alain

Source: Journal of Pharmacokinetics and Pharmacodynamics, Volume 34, Number 2, April 2007 , pp. 157-181(25)

Publisher: Springer

Application of Scaling Factors in Simultaneous Modeling of Microarray Data from Diverse Chips

Authors: Yao, Zhenling; Zhao, Baiteng; Hoffman, Eric; Ghimbovschi, Svetlana; DuBois, Debra; Almon, Richard; Jusko, William

Source: Pharmaceutical Research, Volume 24, Number 4, April 2007 , pp. 643-649(7)

Publisher: Springer

Modeling Cardiac Uptake and Negative Inotropic Response of Verapamil in Rat Heart: Effect of Amiodarone

Authors: Sermsappasuk, Pakawadee; Abdelrahman, Osama; Weiss, Michael

Source: Pharmaceutical Research, Volume 24, Number 1, January 2007 , pp. 48-57(10)

Publisher: Springer

Use of Three-Dimensional Tissue Cultures to Model Extravascular Transport and Predict In Vivo Activity of Hypoxia-Targeted Anticancer Drugs

Authors: Hicks, Kevin O.; Pruijn, Frederik B.; Secomb, Timothy W.; Hay, Michael P.; Hsu, Richard; Brown, J. Martin; Denny, William A.; Dewhirst, Mark W.; Wilson, William R.

Source: Journal of the National Cancer Institute, Volume 98, Number 16, 16 August 2006 , pp. 1118-1128(11)

Publisher: Oxford University Press

Pharmacokinetic/Pharmacodynamic Modeling of Total Lymphocytes and Selected Subtypes After Oral Budesonide

Authors: Stark, Jeffrey; Werner, Sybille; Homrighausen, Susanne; Tang, Yufei; Krieg, Michael; Derendorf, Hartmut; Moellmann, Helmut; Hochhaus, Guenther

Source: Journal of Pharmacokinetics and Pharmacodynamics, Volume 33, Number 4, August 2006 , pp. 441-459(19)

Publisher: Springer

How Modeling and Simulation Have Enhanced Decision Making in New Drug Development

Authors: Miller, Raymond; Ewy, Wayne; Corrigan, Brian; Ouellet, Daniele; Hermann, David; Kowalski, Kenneth; Lockwood, Peter; Koup, Jeffrey; Donevan, Sean; El-Kattan, Ayman; Li, Cheryl; Werth, John; Feltner, Douglas; Lalonde, Richard

Source: Journal of Pharmacokinetics and Pharmacodynamics, Volume 32, Number 2, April 2005 , pp. 185-197(13)

Publisher: Springer

Control-Relevant Modeling of the Antitumor Effects of 9-Nitrocamptothecin in SCID Mice Bearing HT29 Human Colon Xenografts

Authors: Harrold, John; Eiseman, Julie; Joseph, Erin; Strychor, Sandra; Zamboni, William; Parker, Robert

Source: Journal of Pharmacokinetics and Pharmacodynamics, Volume 32, Number 1, February 2005 , pp. 65-83(19)

Publisher: Springer

The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies

Authors: GAUSSEM, P.; RENY, J.-L.; THALAMAS, C.; CHATELAIN, N.; KROUMOVA, M.; JUDE, B.; BONEU, B.; FIESSINGER, J.-N.

Source: Journal of Thrombosis and Haemostasis, Volume 3, Number 7, July 2005 , pp. 1437-1445(9)

Publisher: Blackwell Publishing

Pharmacodynamic Assessment of the Benztropine Analogues AHN-1055 and AHN-2005 Using Intracerebral Microdialysis to Evaluate Brain Dopamine Levels and Pharmacokinetic/Pharmacodynamic Modeling

Authors: Raje, Sangeeta; Cornish, Jennifer; Newman, Amy H.; Cao, Jianjing; Katz, Jonathan L.; Eddington, Natalie D.

Source: Pharmaceutical Research, Volume 22, Number 4, April 2005 , pp. 603-612(10)

Publisher: Springer

Pharmacokinetics/Pharmacodynamics (PK/PD) Modeling of Risks of Kidney Toxicity from Exposure to Cadmium: Estimates of Dietary Risks in the U.S. Population

Authors: Gary Diamond; William Thayer; Harlal Choudhury

Source: Journal of Toxicology and Environmental Health Part A, Volume 66, Number 22, January 2003 , pp. 2141-2164(24)

Publisher: Taylor and Francis Ltd

In vivo multi-tissue corticosteroid microarray time series available online at Public Expression Profile Resource (PEPR)

Authors: Almon, Richard R; Chen, Josephine; Snyder, Grayson; DuBois, Debra C; Jusko, William J; Hoffman, Eric P

Source: Pharmacogenomics, Volume 4, Number 6, November 2003 , pp. 791-799(9)

Publisher: Future Medicine