Search Results

Phosphoinositide 3-Kinase Gamma (PI3Kγ) Inhibitors for the Treatment of Inflammation and Autoimmune Disease

Authors: Venable, Jennifer D.; Ameriks, Michael K.; Blevitt, Jonathan M.; Thurmond, Robin L.; Fung-Leung, Wai-Ping

Source: Recent Patents on Inflammation & Allergy Drug Discovery, Volume 4, Number 1, January 2010 , pp. 1-15(15)

Publisher: Bentham Science Publishers

The PKB/AKT Pathway in Cancer

Author: Carnero, Amancio

Source: Current Pharmaceutical Design, Volume 16, Number 1, January 2010 , pp. 34-44(11)

Publisher: Bentham Science Publishers

Pi3K-mTOR Signaling and AMOG Expression in Epilepsy-associated Glioneuronal Tumors

Authors: Boer, Karin; Troost, Dirk; Timmermans, Wendy; van Rijen, Peter C.; Spliet, Wim G.M.; Aronica, Eleonora

Source: Brain Pathology, Volume 20, Number 1, January 2010 , pp. 234-244(11)

Publisher: Blackwell Publishing

ACh receptors link two signaling pathways to neuroprotection against glutamate-induced excitotoxicity in isolated RGCs

Authors: Asomugha, Chinwe O.; Linn, David M.; Linn, Cindy L.

Source: Journal of Neurochemistry, Volume 112, Number 1, January 2010 , pp. 214-226(13)

Publisher: Blackwell Publishing

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells

Author: Sekido, Yoshitaka

Source: Cancer Science, Volume 101, Number 1, January 2010 , pp. 1-6(6)

Publisher: Blackwell Publishing

Independent and cooperative roles of tumor necrosis factor-α, nuclear factor-κB, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of MC3T3-E1 osteoblast-like cells

Authors: Graham, Tisheeka R.; Agrawal, Krishna C.; Abdel-Mageed, Asim B.

Source: Cancer Science, Volume 101, Number 1, January 2010 , pp. 103-111(9)

Publisher: Blackwell Publishing

Influence of hepatic artery occlusion on tumor growth and metastatic potential in a human orthotopic hepatoma nude mouse model: Relevance of epithelial-mesenchymal transition

Authors: Liu, Liang; Ren, Zheng-Gang; Shen, Yuan; Zhu, Xiao-Dong; Zhang, Wei; Xiong, Wei; Qin, Yi; Tang, Zhao-You

Source: Cancer Science, Volume 101, Number 1, January 2010 , pp. 120-128(9)

Publisher: Blackwell Publishing

Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways

Author: Lackner, Mark R

Source: Expert Review of Molecular Diagnostics, Volume 10, Number 1, January 2010 , pp. 75-87(13)

Publisher: Expert Reviews

Insulin/PI3K signaling protects dentate neurons from oxygen-glucose deprivation in organotypic slice cultures

Authors: Sun, Xiaolu; Yao, Hang; Douglas, Robert M.; Gu, Xiang Q.; Wang, Juan; Haddad, Gabriel G.

Source: Journal of Neurochemistry, Volume 112, Number 2, January 2010 , pp. 377-388(12)

Publisher: Blackwell Publishing

Monosodium urate crystals in inflammation and immunity

Authors: Shi, Yan; Mucsi, Ashley D.; Ng, Gilbert

Source: Immunological Reviews, Volume 233, Number 1, January 2010 , pp. 203-217(15)

Publisher: Blackwell Publishing

Leptin and the Regulation of Renal Sodium Handling and Renal Na+- Transporting ATPases: Role in the Pathogenesis of Arterial Hypertension

Author: Beltowski, Jerzy

Source: Current Cardiology Reviews, Volume 6, Number 1, February 2010 , pp. 31-40(10)

Publisher: Bentham Science Publishers

Rosiglitazone via upregulation of Akt/eNOS pathways attenuates dysfunction of endothelial progenitor cells, induced by advanced glycation end products

Authors: Liang, Chun; Ren, Yusheng; Tan, Hongbin; He, Zhiqing; Jiang, Qijun; Wu, Jianxiang; Zhen, Yi; Fan, Min; Wu, Zonggui

Source: British Journal of Pharmacology, Volume 158, Number 8, December 2009 , pp. 1865-1873(9)

Publisher: Blackwell Publishing

Roles of LPA in ovarian cancer development and progression

Authors: Pua, Tarah L; Wang, Feng-qiang; Fishman, David A

Source: Future Oncology, Volume 5, Number 10, December 2009 , pp. 1659-1673(15)

Publisher: Future Medicine

Dual EGFR and COX-2 Inhibition as a Novel Approach to Targeting Head and Neck Squamous Cell Carcinoma

Authors: Kao, J.; Sikora, A. T.; Fu, S.

Source: Current Cancer Drug Targets, Volume 9, Number 8, December 2009 , pp. 931-937(7)

Publisher: Bentham Science Publishers

Bioactive Lipids Lysophosphatidic Acid and Sphingosine 1-Phosphate Mediate Breast Cancer Cell Biological Functions Through Distinct Mechanisms

Authors: Boucharaba, Ahmed; Guillet, Benoit; Menaa, Farid; Hneino, Mohamed; van Wijnen, Andre J.; Philippe, Clézardin; Oliver, Peyruchaud

Source: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, Volume 18, Number 4, 2009 , pp. 173-184(12)

Publisher: Cognizant Communication Corporation

Mitochondrial K_ATP opening confers protection against lethal myocardial injury and ischaemia-induced arrhythmias in the rat heart via PI3K/Akt-dependent and -independent mechanisms

Authors: Matejíková, Jana; Ravingerová, Táňa; Pancza, Dezider; Čarnická, Slávka; Kolář, František

Source: Canadian Journal of Physiology and Pharmacology, Volume 87, Number 12, 1 December 2009 , pp. 1055-1062(8)

Publisher: NRC Research Press

Activation of proinflammatory response in human intestinal epithelial cells following Vibrio cholerae infection through PI3K/Akt pathway

Authors: Bandyopadhaya, Arunava; Bhowmick, Swati; Chaudhuri, Keya

Source: Canadian Journal of Microbiology, Volume 55, Number 11, 1 November 2009 , pp. 1310-1318(9)

Publisher: NRC Research Press

Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway

Authors: Maira, Sauveur-Michel; Furet, Pascal; Stauffer, Frédéric

Source: Future Medicinal Chemistry, Volume 1, Number 1, April 2009 , pp. 137-155(19)

Publisher: Future Science

The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic β-cells

Authors: Glauser, Dominique A.; Schlegel, Werner

Source: Journal of Receptors and Signal Transduction, Volume 29, Number 6, December 2009 , pp. 293-298(6)

Publisher: Informa Healthcare

Molecularly targeted therapies for malignant glioma: rationale for combinatorial strategies

Authors: Thaker, Nikhil G; Pollack, Ian F

Source: Expert Review of Neurotherapeutics, Volume 9, Number 12, December 2009 , pp. 1815-1836(22)

Publisher: Expert Reviews