Search Results

Emerging Raf inhibitors

Authors: McCubrey, James A; Steelman, Linda S; Abrams, Steven L; Chappell, William H; Russo, Suzanne; Ove, Roger; Milella, Michele; Tafuri, Agostino; Lunghi, Paolo; Bonati, Antonio; Stivala, Franca; Nicoletti, Ferdinando; Libra, Massimo; Martelli, Alberto M; Montalto, Giuseppe; Cervello, Melchiorre

Source: Expert Opinion on Emerging Drugs, Volume 14, Number 4, December 2009 , pp. 633-648(16)

Publisher: Informa Healthcare

Effect of inhibition of extracellular signal-regulated kinase on relaxations to β-adrenoceptor agonists in porcine isolated blood vessels

Authors: Uhiara, CO; Alexander, SPH; Roberts, RE

Source: British Journal of Pharmacology, Volume 158, Number 7, December 2009 , pp. 1713-1719(7)

Publisher: Blackwell Publishing

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

Author: Ludwig, Stephan

Source: Journal of Antimicrobial Chemotherapy, Volume 64, Number 1, 14 July 2009 , pp. 1-4(4)

Publisher: Oxford University Press

Functional antagonism of IL-1α induced gene expression profiles define the cAMP/PKA pathway as a unique regulator of IL-1α signaling networks

Authors: Murray, David L.; Johnson, Eric N.; Wang, Ping; Gauthier, Josee; Bing, Nan; Vanderwall, Dana; Xu, Zangwei; Jensen, David; Cox, Richard F.; Kostura, Matthew; Sorensen, Scott D.

Source: Journal of Receptors and Signal Transduction, Volume 29, Number 5, October 2009 , pp. 246-256(11)

Publisher: Informa Healthcare

Cross-regulation between β₁- and β₃-adrenoceptors following chronic β-adrenergic stimulation in neonatal rat cardiomyocytes

Authors: Ufer, Christoph; Germack, Renée

Source: British Journal of Pharmacology, Volume 158, Number 1, September 2009 , pp. 300-313(14)

Publisher: Blackwell Publishing

Signal pathways regulating hyaluronan secretion into static and cycled synovial joints of rabbits

Authors: Ingram, K. R.; Wann, A. K. T.; Wingate, R. M.; Coleman, P. J.; McHale, N.; Levick, J. R.

Source: The Journal of Physiology, Volume 587, Number 17, September 2009 , pp. 4361-4376(16)

Publisher: Blackwell Publishing

Development of a novel chemical class of BRAF inhibitors offers new hope for melanoma treatment

Authors: Smalley, Keiran SM; Flaherty, Keith T

Source: Future Oncology, Volume 5, Number 6, August 2009 , pp. 775-778(4)

Publisher: Future Medicine

Cot/Tpl-2 Protein Kinase as a Target for the Treatment of Inflammatory Disease

Authors: George, D.; Salmeron, A.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 7, May 2009 , pp. 611-622(12)

Publisher: Bentham Science Publishers

CGRP stimulation of iNOS and NO release from trigeminal ganglion glial cells involves mitogen-activated protein kinase pathways

Authors: Vause, C. V.; Durham, P. L.

Source: Journal of Neurochemistry, Volume 110, Number 3, August 2009 , pp. 811-821(11)

Publisher: Blackwell Publishing

Developmental Abnormalities and Cancer Predisposition in Neurofibromatosis Type 1

Authors: Larizza, Lidia; Gervasini, Cristina; Natacci, Federica; Riva, Paola

Source: Current Molecular Medicine, Volume 9, Number 5, June 2009 , pp. 634-653(20)

Publisher: Bentham Science Publishers

Signaling Intermediates (PI3K/PTEN/AKT/mTOR and RAF/MEK/ERK Pathways) as Therapeutic Targets for Anti-Cancer and Anti-Angiogenesis Treatments

Authors: Ciuffreda, Ludovica; McCubrey, James A.; Milella, Michele

Source: Current Signal Transduction Therapy, Volume 4, Number 2, May 2009 , pp. 130-143(14)

Publisher: Bentham Science Publishers

IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways

Authors: Bibollet-Bahena, Olivia; Almazan, Guillermina

Source: Journal of Neurochemistry, Volume 109, Number 5, June 2009 , pp. 1440-1451(12)

Publisher: Blackwell Publishing

Breast cancer resistance protein/ABCG2 is differentially regulated downstream of extracellular signal-regulated kinase

Authors: Imai, Yasuo; Ohmori, Kyoko; Yasuda, Shin'ichi; Wada, Mariko; Suzuki, Tsukasa; Fukuda, Kazunori; Ueda, Yoshihiko

Source: Cancer Science, Volume 100, Number 6, June 2009 , pp. 1118-1127(10)

Publisher: Blackwell Publishing

Effect of inhibitors of mitogen-activated protein kinase kinase on α_1B-adrenoceptor phosphorylation

Authors: Alcántara-Hernández, R.; Adolfo García-Sáinz, J.

Source: Autonomic & Autacoid Pharmacology, Volume 29, Numbers 1-2, January 2009 , pp. 13-23(11)

Publisher: Blackwell Publishing

Cholesterol Oxidation Products and Disease: An Emerging Topic of Interest in Medicinal Chemistry

Authors: Sottero, Barbara; Gamba, Paola; Gargiulo, Simona; Leonarduzzi, Gabriella; Poli, Giuseppe

Source: Current Medicinal Chemistry, Volume 16, Number 6, February 2009 , pp. 685-705(21)

Publisher: Bentham Science Publishers

Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/ MEK/ERK Pathway

Author: Wong, Kwong-Kwok

Source: Recent Patents on Anti-Cancer Drug Discovery, Volume 4, Number 1, January 2009 , pp. 28-35(8)

Publisher: Bentham Science Publishers

Helicobacter pylori activate epidermal growth factor receptor- and phosphatidylinositol 3-OH kinase-dependent Akt and glycogen synthase kinase 3β phosphorylation

Authors: Tabassam, Fazal H.; Graham, David Y.; Yamaoka, Yoshio

Source: Cellular Microbiology, Volume 11, Number 1, January 2009 , pp. 70-82(13)

Publisher: Blackwell Publishing

Detection of BRAF V600E mutation by pyrosequencing

Authors: Tan, Yi Hui; Liu, Yanqun; Eu, Kong Weng; Ang, Pei Woon; Li, Wei Qi; Salto-Tellez, Manuel; Iacopetta, Barry; Soong, Richie

Source: Pathology, Volume 40, Number 3, March 2008 , pp. 295-298(4)

Publisher: Informa Healthcare

New treatment options for advanced pancreatic cancer

Authors: Middleton, Gary; Ghaneh, Paula; Costello, Eithne; Greenhalf, William; Neoptolemos, John P

Source: Expert Review of Gastroenterology and Hepatology, Volume 2, Number 5, October 2008 , pp. 673-696(24)

Publisher: Expert Reviews

Biologic therapies for advanced pancreatic cancer

Authors: He, Aiwu Ruth; Lindenberg, Andreas Peter; Marshall, John Lindsay

Source: Expert Review of Anticancer Therapy, Volume 8, Number 8, August 2008 , pp. 1331-1338(8)

Publisher: Expert Reviews