Search Results

Edaravone (MCI-186), a free radical scavenger, attenuates retinal ischemia/reperfusion injury in rats

Authors: SONG, Yi; GONG, Yuan-yuan; XIE, Zheng-gao; LI, Cai-hong; GU, Qing; WU, Xing-wei

Source: Acta Pharmacologica Sinica, Volume 29, Number 7, July 2008 , pp. 823-828(6)

Publisher: Blackwell Publishing

Effects of MCI-186 upon neutrophil-derived active oxygens

Authors: Sumitomo, K.; Shishido, N.; Aizawa, H.; Hasebe, N.; Kikuchi, K.; Nakamura, M.

Source: Redox Report, Volume 12, Number 4, August 2007 , pp. 189-194(6)

Publisher: Maney Publishing

Melatonin influences the proliferative and differentiative activity of neural stem cells

Authors: Moriya, Takahiro; Horie, Nobutaka; Mitome, Masato; Shinohara, Kazuyuki

Source: Journal of Pineal Research, Volume 42, Number 4, May 2007 , pp. 411-418(8)

Publisher: Blackwell Publishing

THE SPECIFIC FREE RADICAL SCAVENGER EDARAVONE SUPPRESSES BLEOMYCIN-INDUCED ACUTE PULMONARY INJURY IN RABBITS

Authors: Asai, Toshihiro; Ohno, Yasushi; Minatoguchi, Shinya; Funaguchi, Norihiko; Yuhgetsu, Hideyuki; Sawada, Masahiro; Takemura, Genzou; Komada, A; Fujiwara, Takako; Fujiwara, Hisayoshi

Source: Clinical and Experimental Pharmacology and Physiology, Volume 34, Numbers 1-2, January 2007 , pp. 22-26(5)

Publisher: Blackwell Publishing

Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats

Authors: Lee, Jeong Hyun; Park, So Youn; Lee, Won Suk; Hong, Ki Whan

Source: Neurological Research, Volume 27, Number 5, July 2005 , pp. 483-492(10)

Publisher: Maney Publishing

MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia–reperfusion injury in rats

Authors: Suzuki, Fumitaka; Hashikura, Yasuhiko; Ise, Hirohiko; Ishida, Akiko; Nakayama, Jun; Takahashi, Masafumi; Miyagawa, Shin-ichi; Ikeda, Uichi

Source: Transplant International, Volume 18, Number 7, July 2005 , pp. 844-853(10)

Publisher: Blackwell Publishing

ONO-1078 reduces NMDA-induced brain injury and vascular cell adhesion molecule-1 expression in rats

Authors: ZHANG, Li-hui; WEI, Er-qing

Source: Acta Pharmacologica Sinica, Volume 26, Number 4, April 2005 , pp. 435-440(6)

Publisher: Blackwell Publishing

Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney

Authors: Doi, Kent; Suzuki, Yoshifumi; Nakao, Akihide; Fujita, Toshiro; Noiri, Eisei

Source: Kidney International, Volume 65, Number 5, May 2004 , pp. 1714-1723(10)

Publisher: Blackwell Publishing

Protective effects of a free radical scavenger, MCI-186, on high-glucose–induced dysfunction of human dermal microvascular endothelial cells

Authors: Dong Jiaojun; Yoshihiro Takami; Hideharu Tanaka; Ryo Yamaguchi; Guo Jingping; Qing Chun; Lu Shuliang; Shuji Shimazaki; Ken Ogo

Source: Wound Repair and Regeneration, Volume 12, Number 6, November 2004 , pp. 607-612(6)

Publisher: Blackwell Publishing

The hydroxyl radical scavenger MCI-186 protects the liver from experimental cold ischaemia–reperfusion injury

Authors: Ninomiya M.; Shimada M.; Harada N.; Soejima Y.; Suehiro T.; Maehara Y.

Source: British Journal of Surgery, Volume 91, Number 2, February 2004 , pp. 184-190(7)

Publisher: John Wiley & Sons, Ltd.

The free radical scavenger MCI-186, reduces lipid peroxidation in hypoxic-ischemic brain damage of the neonatal rat

Authors: Jesmin I., NOOR; Tomoaki, IKEDA; Hiroshi, SAMESHIMA; Tsuyomu, IKENOUE

Source: The Journal of Obstetrics and Gynaecology Research, Volume 29, Number 3, June 2003 , pp. 218-218(1)

Publisher: Blackwell Publishing

Application of in vivo ESR spectroscopy to measurement of cerebrovascular ROS generation in stroke

Authors: Yamato M.; Egashira T.; Utsumi H.

Source: Free Radical Biology and Medicine, Volume 35, Number 12, 15 December 2003 , pp. 1619-1631(13)

Publisher: Elsevier

Synthesis of the metabolites of a free radical scavenger edaravone (MCI-186, Radicut™)

Authors: Watanabe K.; Taniguchi M.; Shinoda M.

Source: Redox Report, Volume 8, Number 3, June 2003 , pp. 157-161(5)

Publisher: Maney Publishing

Protective effect of 3-methyl-1-phenyl-2-pyrazolin-5-one, a free radical scavenger, on acute toxicity of paraquat in mice

Authors: Saibara T.; Toda K.; Wakatsuki A.; Ogawa Y.; Ono M.; Onishi S.

Source: Toxicology Letters, Volume 143, Number 1, 5 June 2003 , pp. 51-54(4)

Publisher: Elsevier

Edaravone protects against ischemia/reperfusion-induced oxidative damage to mitochondria in rat liver

Authors: Okatani Y.; Wakatsuki A.; Enzan H.; Miyahara Y.

Source: European Journal of Pharmacology, Volume 465, Number 1, 28 March 2003 , pp. 163-170(8)

Publisher: Elsevier

Myocardial protection of MCI-186 in rabbit ischemia-reperfusion

Authors: Wu T.-W.; Zeng L.-H.; Wu J.; Fung K.-P.

Source: Life Sciences, Volume 71, Number 19, 27 September 2002 , pp. 2249-2255(7)

Publisher: Elsevier

Effect of the free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats

Authors: Ikeda T.; Xia Y.X.; Kaneko M.; Sameshima H.; Ikenoue T.

Source: Neuroscience Letters, Volume 329, Number 1, 23 August 2002 , pp. 33-36(4)

Publisher: Elsevier

MCI-186 - further histochemical and biochemical evidence of neuroprotection

Authors: Wu T.-W.; Zeng L.-H.; Wu J.; Fung K.-P.

Source: Life Sciences, Volume 67, Number 19, 29 September 2000 , pp. 2387-2392(6)

Publisher: Elsevier

Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat - Implications for endothelial injury from nitric oxide and superoxide

Authors: Nakashima M.; Niwa M.; Iwai T.; Uematsu T.

Source: Free Radical Biology and Medicine, Volume 26, Number 5, March 1999 , pp. 722-729(8)

Publisher: Elsevier

Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion

Authors: Takamatsu H.; Kondo K.; Ikeda Y.; Umemura K.

Source: European Journal of Pharmacology, Volume 362, Number 2, 4 December 1998 , pp. 137-142(6)

Publisher: Elsevier