Search Results

The Small GTPase Activity of the ROC Domain from LRRK2, a Parkinson's Disease Related Protein

Authors: Fu, Qing-Shan; Song, Ai-Xin; Li, Su-Xia; Hu, Hong-Yu

Source: Protein and Peptide Letters, Volume 16, Number 12, December 2009 , pp. 1442-1446(5)

Publisher: Bentham Science Publishers

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment

Authors: Klein, Christian L.; Rovelli, Giorgio; Springer, Wolfdieter; Schall, Christoph; Gasser, Thomas; Kahle, Philipp J.

Source: Journal of Neurochemistry, Volume 111, Number 3, November 2009 , pp. 703-715(13)

Publisher: Blackwell Publishing

Screening for LRRK2 R1441 mutations in a cohort of PSP patients from Germany

Authors: Madžar, D.; Schulte, C.; Gasser, T.

Source: European Journal of Neurology, Volume 16, Number 11, November 2009 , pp. 1230-1232(3)

Publisher: Blackwell Publishing

Kinase Inhibitors as Potential Therapeutics for Acute and Chronic Neurodegenerative Conditions

Author: Cuny, G. D.

Source: Current Pharmaceutical Design, Volume 15, Number 34, December 2009 , pp. 3919-3939(21)

Publisher: Bentham Science Publishers

LRRK2 in Parkinson's disease: building an understanding of disease etiology

Author: Braithwaite, Steven P.

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6427-6427(1)

Publisher: Blackwell Publishing

LRRK2 in Parkinson's disease: biochemical functions

Authors: Anand, Vasanti S.; Braithwaite, Steven P.

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6428-6435(8)

Publisher: Blackwell Publishing

LRRK2 in Parkinson's disease: function in cells and neurodegeneration

Authors: Webber, Philip J.; West, Andrew B.

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6436-6444(9)

Publisher: Blackwell Publishing

LRRK2 in Parkinson's disease: in vivo models and approaches for understanding pathogenic roles

Author: Yue, Zhenyu

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6445-6454(10)

Publisher: Blackwell Publishing

LRRK2 in Parkinson's disease: genetic and clinical studies from patients

Authors: Kumari, Udhaya; Tan, E. K.

Source: FEBS Journal, Volume 276, Number 22, November 2009 , pp. 6455-6463(9)

Publisher: Blackwell Publishing

Etiopathogenesis and Treatment of Parkinson's Disease

Authors: Gallagher, David A.; Schapira, Anthony H.V.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 10, July 2009 , pp. 860-868(9)

Publisher: Bentham Science Publishers

New Molecular Avenues in Parkinson's Disease Therapy

Author: Di Napoli, Mario

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 10, July 2009 , pp. 913-948(36)

Publisher: Bentham Science Publishers

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?

Author: Gillardon, Frank

Source: Journal of Neurochemistry, Volume 110, Number 5, September 2009 , pp. 1514-1522(9)

Publisher: Blackwell Publishing

Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain

Authors: Gao, L.; Gómez-Garre, P.; Díaz-Corrales, F. J.; Carrillo, F.; Carballo, M.; Palomino, A.; Díaz-Martín, J.; Mejías, R.; Vime, P. J.; López-Barneo, J.; Mir, P.

Source: European Journal of Neurology, Volume 16, Number 8, August 2009 , pp. 957-960(4)

Publisher: Blackwell Publishing

Parkinson's Disease and Low Frequency Alleles Found Together Throughout LRRK2

Authors: Paisán-Ruiz, Coro; Washecka, Nicole; Nath, Priti; Singleton, Andrew B.; Corder, Elizabeth H.

Source: Annals of Human Genetics, Volume 73, Number 4, July 2009 , pp. 391-403(13)

Publisher: Blackwell Publishing

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro

Authors: Gloeckner, Christian Johannes; Schumacher, Annette; Boldt, Karsten; Ueffing, Marius

Source: Journal of Neurochemistry, Volume 109, Number 4, May 2009 , pp. 959-968(10)

Publisher: Blackwell Publishing

Investigation of leucine-rich repeat kinase 2: Enzymological properties and novel assays

Authors: Anand, Vasanti S.; Reichling, Laurie J.; Lipinski, Kerri; Stochaj, Wayne; Duan, Weili; Kelleher, Kerry; Pungaliya, Pooja; Brown, Eugene L.; Reinhart, Peter H.; Somberg, Richard; Hirst, Warren D.; Riddle, Steven M.; Braithwaite, Steven P.

Source: FEBS Journal, Volume 276, Number 2, January 2009 , pp. 466-478(13)

Publisher: Blackwell Publishing

Update on the functional biology of Lrrk2

Author: Melrose, Heather

Source: Future Neurology, Volume 3, Number 6, November 2008 , pp. 669-681(13)

Publisher: Future Medicine

Emerging pathways in genetic Parkinson's disease: tangles, Lewy bodies and LRRK2

Authors: Devine, Michael J.; Lewis, Patrick A.

Source: FEBS Journal, Volume 275, Number 23, December 2008 , pp. 5748-5757(10)

Publisher: Blackwell Publishing

Genetic mouse models for behavioral analysis through transgenic RNAi technology

Authors: Delic; Streif; Deussing; Weber; Ueffing; Hölter; Wurst; Kühn

Source: Genes, Brain & Behavior, Volume 7, Number 7, October 2008 , pp. 821-830(10)

Publisher: Blackwell Publishing

Screening for LRRK2 mutations in patients with Parkinson's disease in Russia: identification of a novel LRRK2 variant

Authors: Pchelina, S. N.; Yakimovskii, A. F.; Emelyanov, A. K.; Ivanova, O. N.; Schwarzman, A. L.; Singleton, A. B.

Source: European Journal of Neurology, Volume 15, Number 7, July 2008 , pp. 692-696(5)

Publisher: Blackwell Publishing