IngentaConnect Search Results

Ansamycin Inhibitors of Hsp90: Nature's Prototype for Anti-Chaperone Therapy

Authors: Porter, James R.; Ge, Jie; Lee, John; Normant, Emmanuel; West, Kip

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1386-1418(33)

Publisher: Bentham Science Publishers

Purine-Scaffold Hsp90 Inhibitors

Authors: Taldone, Tony; Chiosis, Gabriela

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1436-1446(11)

Publisher: Bentham Science Publishers

Alternate Strategies of Hsp90 Modulation for the Treatment of Cancer and Other Diseases

Authors: Brandt, Gary E.L.; Blagg, Brian S.J.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1447-1461(15)

Publisher: Bentham Science Publishers

Update on Hsp90 Inhibitors in Clinical Trial

Authors: Kim, Y. S.; Alarcon, S. V.; Lee, S.; Lee, M.-J.; Giaccone, G.; Neckers, L.; Trepel, J. B.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1479-1492(14)

Publisher: Bentham Science Publishers

Anti-myeloma activity of the novel 2-aminothienopyrimidine Hsp90 inhibitor NVP-BEP800

Authors: Stühmer, Thorsten; Chatterjee, Manik; Grella, Evelyn; Seggewiss, Ruth; Langer, Christian; Müller, Sabine; Schoepfer, Joseph; Garcia-Echeverria, Carlos; Quadt, Cornelia; Jensen, Michael R.; Einsele, Hermann; Bargou, Ralf C.

Source: British Journal of Haematology, Volume 147, Number 3, November 2009 , pp. 319-327(9)

Publisher: Blackwell Publishing

Pathogenesis-targeting therapeutics for spinal and bulbar muscular atrophy (SBMA)

Authors: Suzuki, Keisuke; Kastuno, Masahisa; Banno, Haruhiko; Sobue, Gen

Source: Neuropathology, Volume 29, Number 4, August 2009 , pp. 509-516(8)

Publisher: Blackwell Publishing

HSP90 Inhibitors: Multi-Targeted Antitumor Effects and Novel Combinatorial Therapeutic Approaches in Cancer Therapy

Authors: Hwang, Misun; Moretti, Luigi; Lu, Bo

Source: Current Medicinal Chemistry, Volume 16, Number 24, August 2009 , pp. 3081-3092(12)

Publisher: Bentham Science Publishers

Impact of heat-shock protein 90 on cancer metastasis

Authors: Tsutsumi, Shinji; Beebe, Kristin; Neckers, Len

Source: Future Oncology, Volume 5, Number 5, June 2009 , pp. 679-688(10)

Publisher: Future Medicine

Potent Triazolothione Inhibitor of Heat-Shock Protein-90

Authors: Feldman, Richard I.; Mintzer, Bob; Zhu, Daguang; Wu, James M.; Biroc, Sandra L.; Yuan, Shendong; Emayan, Kumar; Chang, Zheng; Chen, Deborah; Arnaiz, Damian O.; Bryant, Judi; Ge, Xue Snow; Whitlow, Marc; Adler, Marc; Polokoff, Mark A.; Li, Wei-Wei; Ferrer, Mike; Sato, Takashi; Gu, Jian-Ming; Shen, Jun; Tseng, Jih-Lie; Dinter, Harald; Buckman, Brad

Source: Chemical Biology & Drug Design, Volume 74, Number 1, July 2009 , pp. 43-50(8)

Publisher: Blackwell Publishing

Human 90 kDa Heat Shock Protein Hsp90 as a Target for Cancer Therapeutics

Authors: Gava, Lisandra M.; Ramos, Carlos H.I.

Source: Current Chemical Biology, Volume 3, Number 1, January 2009 , pp. 10-21(12)

Publisher: Bentham Science Publishers

Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide- binding Pocket

Authors: Donnelly, Alison; Blagg, Brian S.J.

Source: Current Medicinal Chemistry, Volume 15, Number 26, November 2008 , pp. 2702-2717(16)

Publisher: Bentham Science Publishers

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models

Authors: Banerji, Udai; Sain, Nivedita; Sharp, Swee; Valenti, Melanie; Asad, Yasmin; Ruddle, Ruth; Raynaud, Florence; Walton, Michael; Eccles, Suzanne; Judson, Ian; Jackman, Ann; Workman, Paul

Source: Cancer Chemotherapy and Pharmacology, Volume 62, Number 5, October 2008 , pp. 769-778(10)

Publisher: Springer

Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight

Authors: Baba, Taisuke; Nishimura, Masuhiro; Kuwahara, Yoshikazu; Ueda, Nobuhiko; Naitoh, Shinsaku; Kume, Makoto; Yamamoto, Yuzo; Fujita, Jun; Funae, Yoshihiko; Fukumoto, Manabu

Source: Pathology International, Volume 58, Number 9, September 2008 , pp. 589-595(7)

Publisher: Blackwell Publishing

Editorial [ Hot Topic: Novel Medicinal Chemistry Approaches to New Anti-cancer Agents (Guest Editor: Diane H. Boschelli) ]

Author: Boschelli, Diane H.

Source: Current Topics in Medicinal Chemistry, Volume 8, Number 10, July 2008 , pp. 840-840(1)

Publisher: Bentham Science Publishers

Oncologic, Endocrine & Metabolic Emerging drugs in B-cell non-Hodgkin's lymphoma

Authors: Kassam, Shireen; Montoto, Silvia

Source: Expert Opinion on Emerging Drugs, Volume 13, Number 2, June 2008 , pp. 323-343(21)

Publisher: Informa Healthcare

Membranes: a meeting point for lipids, proteins and therapies

Authors: Escribá, Pablo V.; González-Ros, José M.; Goñi, Félix M.; Kinnunen, Paavo K. J.; Vigh, Lászlo; Sánchez-Magraner, Lissete; Fernández, Asia M.; Busquets, Xavier; Horváth, Ibolya; Barceló-Coblijn, Gwendolyn

Source: Journal of Cellular and Molecular Medicine, Volume 12, Number 3, June 2008 , pp. 829-875(47)

Publisher: Blackwell Publishing

HER-2 Positive Breast Cancer: What Else Beyond Trastuzumab-Based Therapy?

Authors: Widakowich, Christian; Dinh, Phuong; Azambuja, Evandro d.; Awada, Ahmad; Piccart-Gebhart, Martine

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 5, June 2008 , pp. 488-496(9)

Publisher: Bentham Science Publishers

Structural Models and Binding Site Prediction of the C-terminal Domain of Human Hsp90: A New Target for Anticancer Drugs

Authors: Sgobba, Miriam; Degliesposti, Gianluca; Ferrari, Anna Maria; Rastelli, Giulio

Source: Chemical Biology & Drug Design, Volume 71, Number 5, May 2008 , pp. 420-433(14)

Publisher: Blackwell Publishing

Heat shock protein 90: The cancer chaperone

Author: Neckers, Len

Source: Journal of Biosciences, Volume 32, Number 3, April 2007 , pp. 517-530(14)

Publisher: Springer

Trichosanthin down-regulated p210^Bcr-Abl and enhanced imatinib-induced growth arrest in chronic myelogenous leukemia cell line K562

Authors: Zhang, Kunzhong; Xu, Jianhua; Huang, Xiuwang; Wu, Lixian; Wen, Caixia; Hu, Yingying; Su, Yu; Chen, Yuanzhong; Zhang, Zhiqiang

Source: Cancer Chemotherapy and Pharmacology, Volume 60, Number 4, September 2007 , pp. 581-587(7)

Publisher: Springer