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Crystal structure of Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyl transferase L160I mutant − insights into inhibitor design

Authors: Chen, Qiang; You, Delin; Liang, Yuhe; Su, Xiaodong; Gu, Xiaocheng; Luo, Ming; Zheng, Xiaofeng

Source: FEBS Journal, Volume 274, Number 17, September 2007 , pp. 4408-4415(8)

Publisher: Blackwell Publishing

Acute renal failure from xanthine nephropathy during management of acute leukemia

Authors: LaRosa, Christopher; McMullen, Laura; Bakdash, Suzanne; Ellis, Demetrius; Krishnamurti, Lakshmanan; Wu, Hsi-Yang; Moritz, Michael

Source: Pediatric Nephrology, Volume 22, Number 1, January 2007 , pp. 132-135(4)

Publisher: Springer

Evaluation of the potential genotoxicity of the phosphate binder lanthanum carbonate

Authors: Damment, S.J.P.; Beevers, C.; Gatehouse, D.G.

Source: Mutagenesis, Volume 20, Number 1, January 2005 , pp. 29-37(9)

Publisher: Oxford University Press

New targets for an old drug: II. Hypoxanthine-guanine amidophosphoribosyltransferase as a new pharmacodynamic target of methotrexate

Authors: Slon-Usakiewicz, Jacek; Pasternak, Andrew; Reid, Neil; Toledo-Sherman, Leticia

Source: Clinical Proteomics, Volume 1, Numbers 3-4, September 2004 , pp. 227-234(8)

Publisher: Humana Press

Bioassay for detection of methotrexate in serum

Authors: Lathouder S.d.; Gerards A.; de Groot E.; Valkhof M.; Dijkmans B.; Aarden L.

Source: Scandinavian Journal of Rheumatology, Volume 33, Number 3, May 2004 , pp. 167-173(7)

Publisher: Informa Healthcare

The mutagenic potentiator effect of chlorophyllin by the HGPRT assay

Authors: Davidson Negraes P.; Quinzani Jordao B.; Pimenta Vicentini V.E.; Mantovani M.S.

Source: Toxicology in Vitro, Volume 18, Number 1, February 2004 , pp. 147-149(3)

Publisher: Elsevier

Cloning, purification, and characterization of thermostable hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis

Authors: Chen Q.; You D.; Hu M.; Gu X.; Luo M.; Lu S.

Source: Protein Expression and Purification, Volume 32, Number 2, December 2003 , pp. 239-245(7)

Publisher: Elsevier

APRT from erythrocytes of HGPRT deficient patients: Kinetic, regulatory and thermostability properties

Authors: Crespillo J.; Llorente P.; Argom´niz L.

Source: Molecular and Cellular Biochemistry, Volume 254, Numbers 1-2, 200312 , pp. 359-363(5)

Publisher: Springer

In vitro toxicity and mutagenicity of CoCrMo and Ti6Al wear particles

Authors: Katzer A.; Hockertz S.; Buchhorn G.H.; Loehr J.F.

Source: Toxicology, Volume 190, Number 3, 28 August 2003 , pp. 145-154(10)

Publisher: Elsevier

The DNA methylation inhibitor 5-azacytidine modulates 6-thioguanine toxicity in mammalian cells

Authors: Sciandrello G.; Caradonna F.; Barbata G.

Source: Toxicology Letters, Volume 142, Number 1, 30 April 2003 , pp. 29-35(7)

Publisher: Elsevier

Inhibition of inosine monophosphate dehydrogenase (IMPDH) by the antiviral compound, 2-vinylinosine monophosphate

Authors: Pal S.; Bera B.; Nair V.

Source: Bioorganic and Medicinal Chemistry, Volume 10, Number 11, November 2002 , pp. 3615-3618(4)

Publisher: Elsevier

Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase

Authors: Monzani P.S.; Alfonzo J.D.; Simpson L.; Oliva G.; Thiemann O.H.

Source: Biochimica et Biophysica Acta - Proteins and Proteomics, Volume 1598, Number 1, 29 July 2002 , pp. 3-9(7)

Publisher: Elsevier

Enantioselective route to key intermediates in the synthesis of carbocyclic phosphoribosyltransferase transition state analogues

Authors: Ahmadian M.; Khare N.K.; Riordan J.M.; Klon A.E.; Borhani D.W.

Source: Tetrahedron, Volume 57, Number 50, 10 December 2001 , pp. 9899-9909(11)

Publisher: Elsevier

Hypoxanthine-guanine phosphoribosyltransferase-deficiency produces aberrant neurite outgrowth of rodent neuroblastoma used to model the neurological disorder Lesch Nyhan syndrome

Author: Connolly G.P.

Source: Neuroscience Letters, Volume 314, Number 1, 13 November 2001 , pp. 61-64(4)

Publisher: Elsevier

Abnormal development of hypoxanthine-guanine phosphoribosyltransferase-deficient CNS neuroblastoma

Authors: Connolly G.P.; Duley J.A.; Stacey N.C.

Source: Brain Research, Volume 918, Number 1, 9 November 2001 , pp. 20-27(8)

Publisher: Elsevier

Requirement of de novo protein synthesis for aminopterin-induced apoptosis in a mouse myeloma cell line

Authors: Chung Y.-H.; Youn J.; Choi Y.; Jin Paik D.; Cho Y.-J.

Source: Immunology Letters, Volume 77, Number 3, 2 July 2001 , pp. 127-131(5)

Publisher: Elsevier

Unusual Substrate Specificity of a Chimeric Hypoxanthine-Guanine Phosphoribosyltransferase Containing Segments from the Plasmodium falciparum and Human Enzymes

Authors: Sujay Subbayya I.N.; Sukumaran S.; Shivashankar K.; Balaram H.

Source: Biochemical and Biophysical Research Communications, Volume 272, Number 2, 7 June 2000 , pp. 596-602(7)

Publisher: Elsevier

ROLE OF IRON IN THE CELLULAR EFFECTS OF ASBESTOS

Authors: Aust, Ann E.; Lund, Loren G.; Chao, Chien-Chung; Park, Sun-Hee; Fang, Ruihua

Source: Inhalation Toxicology, Volume 12, Supplement 1 to issue 10, 1 October 2000 , pp. 75-80(6)

Publisher: Informa Healthcare

2,4-PENTANEDIONE: EVALUATION OF THE GENOTOXIC POTENTIAL IN VITRO AND IN VIVO

Authors: Vergnes J. S.; Ballantyne B.

Source: Toxic Substance Mechanisms, Volume 19, Number 3, 1 July 2000 , pp. 151-175(25)

Publisher: Taylor and Francis Ltd

Substrate Deformation in a Hypoxanthine-Guanine Phosphoribosyltransferase Ternary Complex - The Structural Basis for Catalysis

Authors: Heroux&unknown; A.; White E.L.; Ross L.J.; Kuzin A.P.; Borhani&unknown; D.W.

Source: Structure, Volume 8, Number 12, December 2000 , pp. 1309-1318(10)

Publisher: Elsevier