Search Results

S100A1: Structure, Function, and Therapeutic Potential

Authors: Wright, Nathan T.; Cannon, Brian R.; Zimmer, Danna B.; Weber, David J.

Source: Current Chemical Biology, Volume 3, Number 2, May 2009 , pp. 138-145(8)

Publisher: Bentham Science Publishers

Novel class of hybrid natural products as antidiabetic agents

Authors: Raj, Kanwal; Misra, Namita; Pachauri, Geetali; Sharma, Mithelesh; Tamrakar, Akhilesh Kumar; Singh, Amar Bahadur; Srivastava, Arvind Kumar; Phani Kiran, K.; Narasimha Rao, C.V.; Prubhu, S. R.

Source: Natural Product Research, Volume 23, Number 1, October 2009 , pp. 60-69(10)

Publisher: Taylor and Francis Ltd

Editorial [Hot Topic: The Medicinal Chemistry of Glycosidase Inhibitors(Guest Editors: Seiichiro Ogawa and Hideya Yuasa)]

Authors: Ogawa, Seiichiro; Yuasa, Hideya

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 1, January 2009 , pp. 1-2(2)

Publisher: Bentham Science Publishers

New Inhibitors of Glycogen Phosphorylase as Potential Antidiabetic Agents

Authors: Somsak, L.; Czifrak, K.; Toth, M.; Bokor, E.; Chrysina, E. D.; Alexacou, K.-M.; Hayes, J. M.; Tiraidis, C.; Lazoura, E.; Leonidas, D. D.; Zographos, S. E.; Oikonomakos, N. G.

Source: Current Medicinal Chemistry, Volume 15, Number 28, December 2008 , pp. 2933-2983(51)

Publisher: Bentham Science Publishers

Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs

Authors: Hampson, L.; Mackin, P.; Agius, L.

Source: Diabetologia, Volume 50, Number 8, August 2007 , pp. 1743-1751(9)

Publisher: Springer

Impact of Weight-Loss Medications on the Cardiovascular System: Focus on Current and Future Anti-Obesity Drugs

Authors: Drolet, Benoit; Simard, Chantale; Poirier, Paul

Source: American Journal of Cardiovascular Drugs, Volume 7, Number 4, 2007 , pp. 273-288(16)

Publisher: Adis International

Glycogen Phosphorylase Inhibitors

Authors: Henke, Brad R.; Sparks, Steven M.

Source: Mini Reviews in Medicinal Chemistry, Volume 6, Number 8, August 2006 , pp. 845-857(13)

Publisher: Bentham Science Publishers

Glycogen phosphorylase inhibition as a therapeutic target: a review of the recent patent literature

Authors: Baker, David J; Greenhaff, Paul L; Timmons, James A

Source: Expert Opinion on Therapeutic Patents, Volume 16, Number 4, 1 April 2006 , pp. 459-466(8)

Publisher: Informa Healthcare

Recent Developments in the Synthesis and Evaluation of Glucose Analog Inhibitors of Glycogen Phosphorylases as Potential Antidiabetic Agents

Authors: Somsak, Laszlo; Nagy, Veronika; Hadady, Zsuzsa; Felfoldi, Nora; Docsa, Tibor; Gergely, Pal

Source: Frontiers in Medicinal Chemistry - Online, Volume 2, Number 1, January 2005 , pp. 253-272(20)

Publisher: Bentham Science Publishers

Intervention of Hepatic Glucose Production. Small Molecule Regulators of Potential Targets for Type 2 Diabetes Therapy

Author: Tjeerd Barf

Source: Mini Reviews in Medicinal Chemistry, Volume 4, Number 8, October 2004 , pp. 897-908(12)

Publisher: Bentham Science Publishers

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b: Comparison with ligand binding to pCDK2-cyclin A complex

Authors: Kosmopoulou, Magda N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Bischler, Nicolas; Eisenbrand, Gerhard; Sakarellos, Constantinos E.; Pauptit, Richard; Oikonomakos, Nikos G.

Source: FEBS Journal, Volume 271, Number 11, June 2004 , pp. 2280-2290(11)

Publisher: Blackwell Publishing

Novel 3,4-Dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a

Authors: Rosauer K.G.; Ogawa A.K.; Willoughby C.A.; Ellsworth K.P.; Geissler W.M.; Myers R.W.; Deng Q.; Chapman K.T.; Harris G.; Moller D.E.

Source: Bioorganic and Medicinal Chemistry Letters, Volume 13, Number 24, 15 December 2003 , pp. 4385-4388(4)

Publisher: Elsevier

Crystallographic Studies on - and -D-glucopyranosyl Formamide Analogues, Inhibitors of Glycogen Phosphorylase

Authors: Leonidas D.D.; Kovács L.; Docsa T.; Gergely P.; Somsák L.; Chrysina E.D.; Bischler N.; Zographos S.E.; Oikonomakos N.G.; Kosmopoulou M.N.

Source: Biocatalysis and Biotransformation, Volume 21, Numbers 4-5, Numbers 4-5/August 2003 , pp. 233-242(10)

Publisher: Informa Healthcare

Alternative binding modes of an inhibitor to two different kinases

Authors: De Moliner, Erika; Brown, Nick R.; Johnson, Louise N.

Source: FEBS Journal, Volume 270, Number 15, August 2003 , pp. 3174-3181(8)

Publisher: Blackwell Publishing

Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis

Authors: Aiston, Susan; Coghlan, Matthew P.; Agius, Loranne

Source: FEBS Journal, Volume 270, Number 13, July 2003 , pp. 2773-2781(9)

Publisher: Blackwell Publishing

Glucose Analog Inhibitors of Glycogen Phosphorylases as Potential Antidiabetic Agents: Recent Developments

Authors: Somsak, L.; Nagy, V.; Hadady, Z.; Docsa, T.; Gergely, P.

Source: Current Pharmaceutical Design, Volume 9, Number 15, June 2003 , pp. 1177-1189(13)

Publisher: Bentham Science Publishers

Regulation of ₁-adrenoceptor-linked phosphoinositide metabolism in cultured glia: involvement of protein phosphatases and kinases

Authors: Assari T.; Cox S.; Munday M.R.; Pearce B.

Source: Cellular Signalling, Volume 15, Number 4, April 2003 , pp. 403-412(10)

Publisher: Elsevier

Potential Drug Targets and Progress Towards Pharmacologic Inhibition of Hepatic Glucose Production

Authors: Kurukulasuriya R.; Link J.T.; Madar D.J.; Pei Z.; Richards S.J.; Rohde J.J.; Souers A.J.; Szczepankiewicz B.G.

Source: Current Medicinal Chemistry, Volume 10, Number 2, January 2003 , pp. 123-153(31)

Publisher: Bentham Science Publishers

Glycogen Phosphorylase as a Molecular Target for Type 2 Diabetes Therapy

Author: Oikonomakos N.G.

Source: Current Protein and Peptide Science, Volume 3, Number 6, December 2002 , pp. 561-586(26)

Publisher: Bentham Science Publishers

Structure-Activity Analysis of the Purine Binding Site of Human Liver Glycogen Phosphorylase

Authors: Ekstrom J.L.; Pauly T.A.; Carty M.D.; Soeller W.C.; Culp J.; Danley D.E.; Hoover D.J.; Treadway J.L.; Gibbs E.M.; Fletterick R.J.; Day Y.S.N.; Myszka D.G.; Rath V.L.

Source: Chemistry & Biology, Volume 9, Number 8, August 2002 , pp. 915-924(10)

Publisher: Elsevier