Search Results

Structure-activity relationships of the glucuronidation of flavonoids by human glucuronosyltransferases

Authors: Wong, Yin Cheong; Zhang, Li; Lin, Ge; Zuo, Zhong

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 11, November 2009 , pp. 1399-1419(21)

Publisher: Informa Healthcare

Effect of telmisartan, valsartan and candesartan on mycophenolate mofetil pharmacokinetics in Japanese renal transplant recipients

Authors: Miura, M.; Satoh, S.; Kagaya, H.; Saito, M.; Inoue, T.; Ohkubo, T.; Habuchi, T.; Suzuki, T.

Source: Journal of Clinical Pharmacy & Therapeutics, Volume 34, Number 6, December 2009 , pp. 683-692(10)

Publisher: Blackwell Publishing

Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion

Authors: He, Xi; Hesse, Leah M.; Hazarika, Suwagmani; Masse, Gina; Harmatz, Jerold S.; Greenblatt, David J.; Court, Michael H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 5, November 2009 , pp. 721-730(10)

Publisher: Blackwell Publishing

Oral bioavailability and brain penetration of (−)-stepholidine, a tetrahydroprotoberberine agonist at dopamine D₁ and antagonist at D₂ receptors, in rats

Authors: Sun, Yan; Dai, Jieyu; Hu, Zheyi; Du, Feifei; Niu, Wei; Wang, Fengqing; Liu, Fei; Jin, Guozhang; Li, Chuan

Source: British Journal of Pharmacology, Volume 158, Number 5, November 2009 , pp. 1302-1312(11)

Publisher: Blackwell Publishing

Studies on induction of lamotrigine metabolism in transgenic UGT1 mice

Authors: Argikar, U. A.; Senekeo-Effenberger, K.; Larson, E. E.; Tukey, R. H.; Remmel, R. P.

Source: Xenobiotica, Volume 39, Number 11, November 2009 , pp. 826-835(10)

Publisher: Informa Healthcare

Lasofoxifene: a new-generation SERM for the treatment of postmenopausal osteoporosis

Authors: Gennari, Luigi; Merlotti, Daniela; Nuti, Ranuccio

Source: Expert Review of Obstretrics and Gynecology, Volume 4, Number 6, November 2009 , pp. 607-617(11)

Publisher: Expert Reviews

In-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry

Authors: Gorman, Gregory S.; Coward, Lori; Kerstner-Wood, Corenna; Freeman, Lea; Hebert, Charles D.; Kapetanovic, Izet M.

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 10, October 2009 , pp. 1309-1318(10)

Publisher: Pharmaceutical Press

Limited Sampling Models and Bayesian Estimation for Mycophenolic Acid Area under the Curve Prediction in Stable Renal Transplant Patients Co-Medicated with Ciclosporin or Sirolimus

Authors: Musuamba, Flora T.; Rousseau, Annick; Bosmans, Jean-Louis; Senessael, Jean-Jacques; Cumps, Jean; Marquet, Pierre; Wallemacq, Pierre; Verbeeck, Roger K.

Source: Clinical Pharmacokinetics, Volume 48, Number 11, 1 November 2009 , pp. 745-758(14)

Publisher: Adis International

Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor α agonist in preclinical species and human

Authors: Frederick, K.S.; Maurer, T.S.; Kalgutkar, A.S.; Royer, L.J.; Francone, O.L.; Winter, S.M.; Terra, S.G.; Chen, D.; Gao, X.

Source: Xenobiotica, Volume 39, Number 10, October 2009 , pp. 766-781(16)

Publisher: Informa Healthcare

Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: Inhibition by NSAIDs

Authors: Knights, Kathleen M.; Winner, Leanne K.; Elliot, David J.; Bowalgaha, Kushari; Miners, John O.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 3, September 2009 , pp. 402-412(11)

Publisher: Blackwell Publishing

Altered expression of MRP2, MRP3 and UGT2B1 in the liver affects the disposition of morphine and its glucuronide conjugate in a rat model of cholestasis

Authors: Hasegawa, Yoshitaka; Kishimoto, Shuichi; Takahashi, Hirokazu; Inotsume, Nobuo; Takeuchi, Yoshikazu; Fukushima, Shoji

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 9, September 2009 , pp. 1205-1210(6)

Publisher: Pharmaceutical Press

Pharmacokinetic Modelling of the Plasma Protein Binding of Mycophenolic Acid in Renal Transplant Recipients

Authors: van Hest, Reinier M.; >Teun van Gelder,; Vulto, Arnold G.; Shaw, Leslie M.; Mathot, Ron A.A.

Source: Clinical Pharmacokinetics, Volume 48, Number 7, 1 July 2009 , pp. 463-476(14)

Publisher: Adis International

UGT1A1, UGT1A6 and UGT1A7 Genetic Analysis: Repercussion for Irinotecan Pharmacogenetics in the São Miguel Island Population (Azores, Portugal)

Authors: Pacheco, Paula R.; Brilhante, Maria J.; Ballart, Cristina; Sigalat, Francesc; Polena, Helena; Cabral, Rita; Branco, Claudia C.; Mota-Vieira, Luisa

Source: Molecular Diagnosis & Therapy, Volume 13, Number 4, 1 August 2009 , pp. 261-268(8)

Publisher: Adis International

Morphine Glucuronidation in Preterm Neonates, Infants and Children Younger than 3 Years

Authors: Knibbe, Catherijne A.J.; Krekels, Elke H.J.; >Johannes N. van den Anker,; DeJongh, Joost; Santen, Gijs W.E.; >Monique van Dijk,; Simons, Sinno H.P.; van Lingen, Richard A.; Jacqz-Aigrain, Evelyne M.; Danhof, Meindert; Tibboel, Dick

Source: Clinical Pharmacokinetics, Volume 48, Number 6, 6 June 2009 , pp. 371-385(15)

Publisher: Adis International

Studies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction

Authors: Zheng, M.; Wang, J.; Lubinski, J.; Flint, O. P.; Krishna, R.; Yao, M.; Pursley, J. M.; Thakur, A.; Boulton, D. W.; Santone, K. S.; Barten, D. M.; Anderson, J. J.; Felsenstein, K. M.; Hansel, S. B.

Source: Xenobiotica, Volume 39, Number 7, July 2009 , pp. 544-555(12)

Publisher: Informa Healthcare

Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect

Authors: Kang, H. E.; Cho, Y. K.; Jung, H. Y.; Choi, K. Y.; Sohn, S. I.; Baek, S. R.; Lee, M. G.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 465-475(11)

Publisher: Informa Healthcare

Raltegravir: A Review of its Use in the Management of HIV Infection in Treatment-Experienced Patients

Authors: Croxtall, Jamie D.; Keam, Susan J.

Source: Drugs, Volume 69, Number 8, 4 June 2009 , pp. 1059-1075(17)

Publisher: Adis International

Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages

Authors: Dao Duong Thi, M.; Helen Grant, M.; Mullen, Alexander B.; Tettey, Justice N. A.; MacKay, Simon P.; Clark, Rachel L.

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 3, March 2009 , pp. 399-406(8)

Publisher: Pharmaceutical Press

Glucuronidation of Buprenorphine and Norbuprenorphine by Human Liver Microsomes and UDP-Glucuronosyltransferases

Authors: Chang, Yan; Moody, David E.

Source: Drug Metabolism Letters, Volume 3, Number 2, April 2009 , pp. 101-107(7)

Publisher: Bentham Science Publishers

Variation in glucuronidation of lamotrigine in human liver microsomes

Authors: Argikar, U. A.; Remmel, R. P.

Source: Xenobiotica, Volume 39, Number 5, May 2009 , pp. 355-363(9)

Publisher: Informa Healthcare