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393 articles with title/keywords/abstract containing First-pass metabolism

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Design and Development of Nanovehicle-Based Delivery Systems for Preventive or Therapeutic Supplementation with Flavonoids

Authors: Leonarduzzi, G.; Testa, G.; Sottero, B.; Gamba, P.; Poli, G.

Source: Current Medicinal Chemistry, Volume 17, Number 1, January 2010 , pp. 74-95(22)

Publisher: Bentham Science Publishers

Content loaded within last 14 days Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action

Authors: Bazzoli, Caroline; Jullien, Vincent; >Clotilde Le Tiec,; Rey, Elisabeth; Mentré, France; Taburet, Anne-Marie

Source: Clinical Pharmacokinetics, Volume 49, Number 1, 1 January 2010 , pp. 17-45(29)

Publisher: Adis International

Content loaded within last 14 days Formulations of Fentanyl for the Management of Pain

Authors: Grape, Sina; Schug, Stephan A.; Lauer, Stefan; Schug, Barbara S.

Source: Drugs, Volume 70, Number 1, 1 January 2010 , pp. 57-72(16)

Publisher: Adis International

Cross-species comparisons of the pharmacokinetics of ibudilast

Authors: Sanftner, L. M.; Gibbons, J. A.; Gross, M. I.; Suzuki, B. M.; Gaeta, F. C. A.; Johnson, K. W.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 964-977(14)

Publisher: Informa Healthcare

Rapid Oral Transmucosal Absorption of Sumatriptan, and Pharmacodynamics in Acute Migraine

Authors: Dilone, Enrique; Bergstrom, David; Cabana, Bernard; Nedumpara, Mercy; Fox, Anthony W.

Source: Headache: The Journal of Head and Face Pain, Volume 49, Number 10, November/December 2009 , pp. 1445-1453(9)

Publisher: Blackwell Publishing

Formulation and evaluation of nasal mucoadhesive microspheres of Sumatriptan succinate

Authors: Jain, Snehal A.; Chauk, Dheeraj S.; Mahajan, Hitendra S.; Tekade, Avinash R.; Gattani, Surendra G.

Source: Journal of Microencapsulation, Volume 26, Number 8, December 2009 , pp. 711-721(11)

Publisher: Informa Healthcare

Inhibition of the active principle of the weak opioid tilidine by the triazole antifungal voriconazole

Authors: Grün, Barbara; Krautter, Stefanie; Riedel, Klaus-Dieter; Mikus, Gerd

Source: British Journal of Clinical Pharmacology, Volume 68, Number 5, November 2009 , pp. 712-720(9)

Publisher: Blackwell Publishing

Trichloroethylene risk assessment: A review and commentary

Authors: Jollow, David J.; Bruckner, James V.; McMillan, David C.; Fisher, Jeffrey W.; Hoel, David G.; Mohr, Lawrence C.

Source: Critical Reviews in Toxicology, Volume 39, Number 9, October 2009 , pp. 782-797(16)

Publisher: Informa Healthcare

Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate

Authors: Fonsi, M.; Fiore, F.; Jones, P.; Kinzel, O.; Laufer, R.; Rowley, M.; Monteagudo, E.

Source: Xenobiotica, Volume 39, Number 10, October 2009 , pp. 722-737(16)

Publisher: Informa Healthcare

Maraviroc modelling strategy: use of early phase 1 data to support a semi-mechanistic population pharmacokinetic model

Authors: Weatherley, Barry; McFadyen, Lynn

Source: British Journal of Clinical Pharmacology, Volume 68, Number 3, September 2009 , pp. 355-369(15)

Publisher: Blackwell Publishing

Contribution of a significant first-pass effect of dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylene dioxybiphenyl-2,2′-dicarboxylate in the liver to its poor bioavailability in rats

Authors: Yu, Kyung-Ha; Lee, Ye-Rie; Ahn, Sung-Hoon; Kim, Dae-Duk; Shim, Chang-Koo; Chung, Suk-Jae

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 9, September 2009 , pp. 1197-1203(7)

Publisher: Pharmaceutical Press

Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein

Authors: Tachibana, T.; Kato, M.; Watanabe, T.; Mitsui, T.; Sugiyama, Y.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 430-443(14)

Publisher: Informa Healthcare

Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect

Authors: Kang, H. E.; Cho, Y. K.; Jung, H. Y.; Choi, K. Y.; Sohn, S. I.; Baek, S. R.; Lee, M. G.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 465-475(11)

Publisher: Informa Healthcare

Pharmacokinetics and drug metabolism in the elderly

Author: Klotz, Ulrich

Source: Drug Metabolism Reviews, Volume 41, Number 2, May 2009 , pp. 67-76(10)

Publisher: Informa Healthcare

Cytochrome P450-mediated metabolism in the human gut wall

Authors: Thelen, Kirstin; Dressman, Jennifer B.

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 5, May 2009 , pp. 541-558(18)

Publisher: Pharmaceutical Press

Effect of hesperidin on the oral pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats

Authors: Cho, Young-Ah; Choi, Dong-Hyun; Choi, Jun-Shik

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 6, June 2009 , pp. 825-829(5)

Publisher: Pharmaceutical Press

Enhanced Transdermal Drug Delivery Techniques: An Extensive Review of Patents

Authors: Rizwan, Mohammad; Aqil, Mohammad; Talegaonkar, Sushama; Azeem, Adnan; Sultana, Yasmin; Ali, Asgar

Source: Recent Patents on Drug Delivery & Formulation, Volume 3, Number 2, June 2009 , pp. 105-124(20)

Publisher: Bentham Science Publishers

The Intestinal Environment in Health and Disease - Recent Insights on the Potential of Intestinal Bacteria to Influence Human Health

Authors: Possemiers, Sam; Grootaert, Charlotte; Vermeiren, Joan; Gross, Gabriele; Marzorati, Massimo; Verstraete, Willy; de Wiele, Tom V.

Source: Current Pharmaceutical Design, Volume 15, Number 18, June 2009 , pp. 2051-2065(15)

Publisher: Bentham Science Publishers

Efficacy and safety of mometasone furoate nasal spray in allergic rhinitis, acute rhinosinusitis and nasal polyposis

Authors: Small, Catherine B; Teper, Ariel

Source: Therapy, Volume 6, Number 3, May 2009 , pp. 393-406(14)

Publisher: Future Medicine

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