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Design, Synthesis, and Biological Evaluation of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as Acetylcholinesterase Inhibitors

Authors: Liu, Si-Jie; Yang, Liu; Liu, Xiao-Guang; Luo, Ying; Cao, Zi-Jian; Cheong Wan, David C.; Lin, Huang-Quan; Hu, Chun

Source: Letters in Drug Design & Discovery, Volume 7, Number 1, January 2010 , pp. 5-8(4)

Publisher: Bentham Science Publishers

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Authors: Goble, Jessica L.; Adendorff, Matthew R.; de Beer, Tjaart A.P.; Stephens, Linda L.; Blatch, Gregory L.

Source: Protein and Peptide Letters, Volume 17, Number 1, January 2010 , pp. 109-120(12)

Publisher: Bentham Science Publishers

Biotransformation studies of prednisone using human intestinal bacteria Part II: Anaerobic incubation and docking studies

Authors: Al-Sanea, Mohamed M.; Abdel-Hafez, Atef A.; Omar, Farghaly A.; Youssef, Adel F.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 6, December 2009 , pp. 1211-1219(9)

Publisher: Informa Healthcare

Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity

Authors: Tripathi, Ashutosh; Durrant, David; Lee, Ray M.; Baruchello, Riccardo; Romagnoli, Romeo; Simoni, Daniele; Kellogg, Glen E.

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 6, December 2009 , pp. 1237-1244(8)

Publisher: Informa Healthcare

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism

Authors: Jaudzems, Kristaps; Kuka, Janis; Gutsaits, Aleksandrs; Zinovjevs, Kirils; Kalvinsh, Ivars; Liepinsh, Edgars; Liepinsh, Edvards; Dambrova, Maija

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 24, Number 6, December 2009 , pp. 1269-1275(7)

Publisher: Informa Healthcare

Tethering of ferredoxin:NADP⁺ oxidoreductase to thylakoid membranes is mediated by novel chloroplast protein TROL

Authors: Jurić, Snježana; Hazler-Pilepić, Kroata; Tomašić, Ana; Lepeduš, Hrvoje; Jeličić, Branka; Puthiyaveetil, Sujith; Bionda, Tihana; Vojta, Lea; Allen, John F.; Schleiff, Enrico; Fulgosi, Hrvoje

Source: The Plant Journal, Volume 60, Number 5, December 2009 , pp. 783-794(12)

Publisher: Blackwell Publishing

Free energy calculations of glycosaminoglycanprotein interactions

Authors: Gandhi, Neha S; Mancera, Ricardo L

Source: Glycobiology, Volume 19, Number 10, 30 October 2009 , pp. 1103-1115(13)

Publisher: Oxford University Press

Insilico analysis of homocamptothecin (hCPT) analogues for anti-tumour activity

Authors: Vadwai, Viral; Devaraj, Shine

Source: International Journal of Bioinformatics Research and Applications, Volume 5, Number 6, 29 October 2009 , pp. 603-615(13)

Publisher: Inderscience Publishers

Modifications of ampicillin structure and its implication: an in-silico approach

Authors: Poddar, Raju; Mathur, Aprajita; Kawalekar, Omkar Uday; Rai, Amit; Bhatnagar, Amogh

Source: International Journal of Bioinformatics Research and Applications, Volume 5, Number 6, 29 October 2009 , pp. 616-624(9)

Publisher: Inderscience Publishers

Cross-docking: increasing platform efficiency by sequencing incoming and outgoing semi-trailers

Authors: Maknoon, Mohammad Yousef; Baptiste, Pierre

Source: International Journal of Logistics, Volume 12, Number 4, August 2009 , pp. 249-261(13)

Publisher: Taylor and Francis Ltd

Protein-Protein Interaction Inhibition (2P2I): Fewer and Fewer Undruggable Targets

Authors: Betzi, Stephane; Guerlesquin, Francoise; Morelli, Xavier

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 10, December 2009 , pp. 968-983(16)

Publisher: Bentham Science Publishers

Exploring Novel Target Space: A Need to Partner High Throughput Docking and Ligand-Based Similarity Searches?

Authors: Shanmugasundaram, Kumaran; Rigby, Alan C.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 10, December 2009 , pp. 984-999(16)

Publisher: Bentham Science Publishers

Structure-Based Virtual Ligand Screening: Recent Success Stories

Authors: Villoutreix, Bruno O.; Eudes, Richard; Miteva, Maria A.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 10, December 2009 , pp. 1000-1016(17)

Publisher: Bentham Science Publishers

Editorial [Hot topic: In Silico Approaches in G Protein-Coupled Receptors (GPCRs) Drug Discovery: Quo Vadis? (Executive Editor: Stefano Moro)]

Author: Moro, Stefano

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 3992-3993(2)

Publisher: Bentham Science Publishers

Rhodopsin and the Others: A Historical Perspective on Structural Studies of G Protein-Coupled Receptors

Authors: Costanzi, Stefano; Siegel, Jeffrey; Tikhonova, Irina G.; Jacobson, Kenneth A.

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 3994-4002(9)

Publisher: Bentham Science Publishers

G Protein-Coupled Receptors: Target-Based In Silico Screening

Authors: Senderowitz, Hanoch; Marantz, Yael

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 4049-4068(20)

Publisher: Bentham Science Publishers

N-Heterocyclic Dipeptide Aldehyde Calpain Inhibitors

Authors: Jones, Seth A.; Jones, Matthew A.; McNabb, Stephen B.; Aitken, Steven G.; Coxon, James M.; Abell, Andrew D.

Source: Protein and Peptide Letters, Volume 16, Number 12, December 2009 , pp. 1466-1472(7)

Publisher: Bentham Science Publishers

An Investigation of the Molecular Interactions of Diacetylcurcumin with Ribonuclease A

Authors: Sahoo, Bijaya K.; Ghosh, Kalyan S.u.n.d.a.r.; Dasgupta, Swagata

Source: Protein and Peptide Letters, Volume 16, Number 12, December 2009 , pp. 1485-1495(11)

Publisher: Bentham Science Publishers

Comparison of the inward- and outward-open homology models and ligand binding of human P-glycoprotein

Authors: Pajeva, Ilza K.; Globisch, Christoph; Wiese, Michael

Source: FEBS Journal, Volume 276, Number 23, December 2009 , pp. 7016-7026(11)

Publisher: Blackwell Publishing

Structural and Computational Biology of the Molecular Chaperone Hsp90: From Understanding Molecular Mechanisms to Computer-Based Inhibitor Design

Authors: Verkhivker, Gennady M.; Dixit, Anshuman; Morra, Giulia; Colombo, Giorgio

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 15, November 2009 , pp. 1369-1385(17)

Publisher: Bentham Science Publishers