Search Results

Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits

Authors: WONG, P. C.; CRAIN, E. J.; WATSON, C. A.; XIN, B.

Source: Journal of Thrombosis and Haemostasis, Volume 7, Number 8, August 2009 , pp. 1313-1320(8)

Publisher: Blackwell Publishing

Pharmacological and clinical profile of bivalirudin in the treatment of patients with acute coronary syndrome

Author: White, Harvey D

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 5, May 2009 , pp. 529-538(10)

Publisher: Informa Healthcare

Aeruginosin Analogs and Other Compounds with Rigid Bicyclic Structure as Potential Antithrombotic Agents

Authors: Wang, Guijun; Goyal, Navneet

Source: Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents), Volume 7, Number 2, April 2009 , pp. 147-165(19)

Publisher: Bentham Science Publishers

Novel oral anticoagulants

Authors: Khoo, C. W.; Tay, K.-H.; Shantsila, E.; Lip, G. Y. H.

Source: International Journal of Clinical Practice, Volume 63, Number 4, April 2009 , pp. 630-641(12)

Publisher: Blackwell Publishing

Vitamin K deficiency amplifies anticoagulation response to ximelagatran: possible implications for direct thrombin inhibitors and their clinical safety

Authors: Kamali, Farhad; Wood, Peter; Ward, Alan

Source: Annals of Hematology, Volume 88, Number 2, February 2009 , pp. 141-149(9)

Publisher: Springer

The effect of ex vivo anticoagulants on whole blood platelet aggregation

Authors: Kalb, Madeleine; Potura, Lukasz; Scharbert, Gisela; Kozek-Langenecker, Sibylle

Source: Platelets, Volume 20, Number 1, February 2009 , pp. 7-11(5)

Publisher: Informa Healthcare

Coadministration of Dabigatran Etexilate and Atorvastatin: Assessment of Potential Impact on Pharmacokinetics and Pharmacodynamics

Authors: Stangier, Joachim; Rathgen, Karin; Stähle, Hildegard; Reseski, Kathrin; Körnicke, Thomas; Roth, Willy

Source: American Journal of Cardiovascular Drugs, Volume 9, Number 1, 2009 , pp. 59-68(10)

Publisher: Adis International

Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development

Authors: Eriksson, Bengt I.; Quinlan, Daniel J.; Weitz, Jeffrey I.

Source: Clinical Pharmacokinetics, Volume 48, Number 1, 2009 , pp. 1-22(22)

Publisher: Adis International

Nucleotide-Derived Thrombin Inhibitors: A New Tool for an Old Issue

Authors: Lancellotti, Stefano; De Cristofaro, Raimondo

Source: Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents), Volume 7, Number 1, January 2009 , pp. 19-28(10)

Publisher: Bentham Science Publishers

Understanding the therapeutic action of recombinant factor VIIa in platelet disorders

Authors: Hers, Ingeborg; Mumford, Andrew

Source: Platelets, Volume 19, Number 8, December 2008 , pp. 571-581(11)

Publisher: Informa Healthcare

Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase

Authors: MÜLLER, J.; FREITAG, D.; MAYER, G.; PÖTZSCH, B.

Source: Journal of Thrombosis and Haemostasis, Volume 6, Number 12, December 2008 , pp. 2105-2112(8)

Publisher: Blackwell Publishing

Heparin-induced thrombocytopenia - therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes

Authors: KRAUEL, K.; FÜRLL, B.; WARKENTIN, T. E.; WEITSCHIES, W.; KOHLMANN, T.; SHEPPARD, J. I.; GREINACHER, A.

Source: Journal of Thrombosis and Haemostasis, Volume 6, Number 12, December 2008 , pp. 2160-2167(8)

Publisher: Blackwell Publishing

Recent Research Developments in the Direct Inhibition of Coagulation Proteinases - Inhibitors of the Initiation Phase

Authors: Henry, Brian L.; Desai, Umesh R.

Source: Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents), Volume 6, Number 4, October 2008 , pp. 323-336(14)

Publisher: Bentham Science Publishers

Percutaneous coronary intervention and the use of glycoprotein IIb/IIIa inhibitors in patients with chronic kidney disease on dialysis: A single center experience

Authors: KHAJA, Azam; GARG, Rajeev; GOVINDARAJAN, Gurushanker; MADSEN, Richard; AGGARWAL, Kul

Source: Hemodialysis International, Volume 12, Supplement 2, October 2008 , pp. S2-S8(1)

Publisher: Blackwell Publishing

New therapeutic option for thromboembolism - dabigatran etexilate

Authors: Nishio, Hitoshi; Ieko, Masahiro; Nakabayashi, Toru

Source: Expert Opinion on Pharmacotherapy, Volume 9, Number 14, October 2008 , pp. 2509-2517(9)

Publisher: Informa Healthcare

Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures

Authors: Ainscow, Edward K; Pilling, James E; Brown, Nick M; Orme, Alexandra T; Sullivan, Michael; Hargreaves, Andy C; Cooke, Emma-Louise; Sullivan, Elaine; Carlsson, Stefan; Andersson, Tommy B

Source: Expert Opinion on Drug Safety, Volume 7, Number 4, July 2008 , pp. 351-365(15)

Publisher: Informa Healthcare

Pharmacological Strategies for Inhibition of Thrombin Activity

Author: Alban, S.

Source: Current Pharmaceutical Design, Volume 14, Number 12, April 2008 , pp. 1152-1175(24)

Publisher: Bentham Science Publishers

Current Update on Glycoprotein IIb-IIIa and Direct Thrombin Inhibition in Percutaneous Coronary Intervention for Non-ST Elevation Acute Coronary Syndromes: Balancing Bleeding Risk and Antiplatelet Efficacy

Authors: KWA, ANDREW T.; ROGERS, JASON H.

Source: Journal of Interventional Cardiology, Volume 21, Number 2, April 2008 , pp. 107-117(11)

Publisher: Blackwell Publishing

Clinical Pharmacokinetics and Pharmacodynamics of the Oral Direct Thrombin Inhibitor Dabigatran Etexilate

Author: Stangier, Joachim

Source: Clinical Pharmacokinetics, Volume 47, Number 5, 2008 , pp. 285-295(11)

Publisher: Adis International

Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo

Authors: NIEMAN, M. T.; BURKE, F.; WARNOCK, M.; ZHOU, Y.; SWEIGART, J.; CHEN, A.; RICKETTS, D.; LUCCHESI, B. R.; CHEN, Z.; DI CERA, E.; HILFINGER, J.; KIM, J. S.; MOSBERG, H. I.; SCHMAIER, A. H.

Source: Journal of Thrombosis and Haemostasis, Volume 6, Number 5, May 2008 , pp. 837-845(9)

Publisher: Blackwell Publishing