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Structure-based Drug Metabolism Predictions for Drug Design

Authors: Sun, Hao; Scott, Dennis O.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 3-17(15)

Publisher: Blackwell Publishing

Inhibition of procarcinogen-bioactivating human CYP1A1, CYP1A2 and CYP1B1 enzymes by melatonin

Authors: Chang, Thomas K. H.; Chen, Jie; Yang, Guixiang; Yeung, Eugene Y. H.

Source: Journal of Pineal Research, Volume 48, Number 1, January 2010 , pp. 55-64(10)

Publisher: Blackwell Publishing

Editorial [Hot topic: Pharmacogenetics: Current Status and Future Perspectives (Executive Editor: Henk-Jan Guchelaar)]

Author: Guchelaar, Henk-Jan

Source: Current Pharmaceutical Design, Volume 16, Number 2, January 2010 , pp. 135-135(1)

Publisher: Bentham Science Publishers

Pharmacogenetics in Oncology: A Promising Field

Authors: Houtsma, D.; Guchelaar, H. J.; Gelderblom, H.

Source: Current Pharmaceutical Design, Volume 16, Number 2, January 2010 , pp. 155-163(9)

Publisher: Bentham Science Publishers

Pharmacogenetics of Phase I and Phase II Drug Metabolism

Authors: Crettol, Severine; Petrovic, Nenad; Murray, Michael

Source: Current Pharmaceutical Design, Volume 16, Number 2, January 2010 , pp. 204-219(16)

Publisher: Bentham Science Publishers

The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to cyp 2c19*2 genotype: first experience in patients

Authors: GURBEL, P. A.; BLIDEN, K. P.; ANTONINO, M. J.; STEPHENS, G.; GRETLER, D. D.; JUREK, M. M.; PAKYZ, R. E.; SHULDINER, A. R.; CONLEY, P. B.; TANTRY, U. S.

Source: Journal of Thrombosis and Haemostasis, Volume 8, Number 1, January 2010 , pp. 43-53(11)

Publisher: Blackwell Publishing

Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy

Authors: FERDER, N. S.; EBY, C. S.; DEYCH, E.; HARRIS, J. K.; RIDKER, P. M.; MILLIGAN, P. E.; GOLDHABER, S. Z.; KING, C. R.; GIRI, T.; MCLEOD, H. L.; GLYNN, R. J.; GAGE, B. F.

Source: Journal of Thrombosis and Haemostasis, Volume 8, Number 1, January 2010 , pp. 95-100(6)

Publisher: Blackwell Publishing

LETTER TO THE EDITOR: Richard Tecwyn Williams (1909-1979): An Appreciation

Author: Jones, A.W.

Source: Journal of Analytical Toxicology, Volume 33, Number 9, November/December 2009 , pp. 623-625(3)

Publisher: Preston Publications

Altered expression of CYP in TSOD mice: a model of type 2 diabetes and obesity

Authors: Kudo, T.; Shimada, T.; Toda, T.; Igeta, S.; Suzuki, W.; Ikarashi, N.; Ochiai, W.; Ito, K.; Aburada, M.; Sugiyama, K.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 889-902(14)

Publisher: Informa Healthcare

C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes

Authors: Zhang, Y.-Y.; Liu, Y.; Zhang, J.-W.; Ge, G.-B.; Liu, H.-X.; Wang, L.-M.; Sun, J.; Yang, L.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 903-914(12)

Publisher: Informa Healthcare

Effects of Escherichia coli lipopolysaccharide on the metformin pharmacokinetics in rats

Authors: Cho, Y. K.; Choi, Y. H.; Kim, S. H.; Lee, M. G.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 946-954(9)

Publisher: Informa Healthcare

Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annua

Authors: Teoh, Keat H.; Polichuk, Devin R.; Reed, Darwin W.; Covello, Patrick S.

Source: Botany, Volume 87, Number 6, 1 June 2009 , pp. 635-642(8)

Publisher: NRC Research Press

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

Authors: Scholz, Ina; Oberwittler, Heike; Riedel, Klaus-Dieter; Burhenne, Jürgen; Weiss, Johanna; Haefeli, Walter E.; Mikus, Gerd

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 906-915(10)

Publisher: Blackwell Publishing

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

Authors: Greenblatt, David J.; Peters, Diane E.; Oleson, Lauren E.; Harmatz, Jerold S.; MacNab, Malcolm W.; Berkowitz, Noah; Zinny, Miguel A.; Court, Michael H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 920-927(8)

Publisher: Blackwell Publishing

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A

Authors: Turpault, Sandrine; Brian, William; Van Horn, Robert; Santoni, Alix; Poitiers, Franck; Donazzolo, Yves; Boulenc, Xavier

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 928-935(8)

Publisher: Blackwell Publishing

Evaluation of Piperonyl Butoxide as a Deltamethrin Synergist for Pyrethroid-Resistant Bed Bugs

Authors: Romero, Alvaro; Potter, Michael F.; Haynes, Kenneth F.

Source: Journal of Economic Entomology, Volume 102, Number 6, December 2009 , pp. 2310-2315(6)

Publisher: Entomological Society of America

3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

Authors: Aboutabl, Mona E; Zordoky, Beshay NM; El-Kadi, Ayman OS

Source: British Journal of Pharmacology, Volume 158, Number 7, December 2009 , pp. 1808-1819(12)

Publisher: Blackwell Publishing

Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo

Authors: Bae, Soo H.; Bae, Soo K.; Lee, Myung G.

Source: Journal of Pharmacy and Pharmacology, Volume 61, Number 12, December 2009 , pp. 1637-1642(6)

Publisher: Pharmaceutical Press

Cytochrome P450 loss-of-function polymorphism genotyping on the Agilent Bioanalyzer and clinical application

Authors: Piatkov, Irina; Jones, Trudi; Rochester, Colin

Source: Pharmacogenomics, Volume 10, Number 12, December 2009 , pp. 1987-1994(8)

Publisher: Future Medicine

The effect of oral lipids and circulating lipoproteins on the metabolism of drugs

Authors: Patel, Jigar P; Brocks, Dion R

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 11, November 2009 , pp. 1385-1398(14)

Publisher: Informa Healthcare