Search Results

Phosphoinositide 3-Kinase Gamma (PI3Kγ) Inhibitors for the Treatment of Inflammation and Autoimmune Disease

Authors: Venable, Jennifer D.; Ameriks, Michael K.; Blevitt, Jonathan M.; Thurmond, Robin L.; Fung-Leung, Wai-Ping

Source: Recent Patents on Inflammation & Allergy Drug Discovery, Volume 4, Number 1, January 2010 , pp. 1-15(15)

Publisher: Bentham Science Publishers

Structural Analysis of DFG-in and DFG-out Dual Src-Abl Inhibitors Sharing a Common Vinyl Purine Template

Authors: Zhou, Tianjun; Commodore, Lois; Huang, Wei-Sheng; Wang, Yihan; Sawyer, Tomi K.; Shakespeare, William C.; Clackson, Tim; Zhu, Xiaotian; Dalgarno, David C.

Source: Chemical Biology & Drug Design, Volume 75, Number 1, January 2010 , pp. 18-28(11)

Publisher: Blackwell Publishing

Crystal chemistry and nomenclature of the lovozerite group

Authors: Pekov, Igor V.; Krivovichev, Sergey V.; Zolotarev, Andrey A.; Yakovenchuk, Viktor N.; Armbruster, Thomas; Pakhomovsky, Yakov A.

Source: European Journal of Mineralogy, Volume 21, Number 5, October 2009 , pp. 1061-1071(11)

Publisher: E. Schweizerbart'sche Verlagsbuchhandlung

Synthesis and Crystal Structure of 7,8-Dihydroquinolino[2,3-a]acridine Derivatives

Authors: Han, Guang-Fan; Wang, Rui-Hua; Zhang, Wen-Tao; Zhao, Yu-Yuan; Xing, Zheng; Dai, Wei

Source: Synthetic Communications, Volume 39, Number 14, January 2009 , pp. 2492-2505(14)

Publisher: Taylor and Francis Ltd

Tuning of emission wavelength in chiral photonic crystals with an anisotropic defect layer

Authors: Gevorgyan, A. H.; Harutyunyan, M. Z.

Source: Journal of Modern Optics, Volume 56, Number 10, June 2009 , pp. 1163-1173(11)

Publisher: Taylor and Francis Ltd

Design of ultra-low and ultra-flattened dispersion single mode photonic crystal fiber by DE/EDA algorithm

Authors: Pourmahayabadi, M.; Mohammad Nejad, S.

Source: Journal of Modern Optics, Volume 56, Number 12, July 2009 , pp. 1348-1357(10)

Publisher: Taylor and Francis Ltd

Conducting Composites and Blends of Polythiophene and Polyoxymethylene

Authors: Ozgun, Aylin; Sari, Bekir; Uygun, Aysegul; Unal, H. Ibrahim; Cakanyildirim, Cetin

Source: International Journal of Polymer Analysis and Characterization, Volume 14, Number 6, August 2009 , pp. 469-480(12)

Publisher: Taylor and Francis Ltd

Facile synthesis of novel 2-(4'-N,N-dimethylbenzylidenoimino)-6-substituted-1,3-benzothiazoles and crystal structures of 2-(4'-N,N-dimethylbenzylidenoimino)-6-chloro-1,3-benzothiazole and the co-crystal of 2-amino-6-nitro-1,3-benzothiazole and 4-(N,N-dimethylamino)benzaldehyde

Authors: Drake, John; Hursthouse, Michael; Kriplani, Prashant; Light, Mark; Ojha, Krishan; Pareek, Pawan; Ratnani, Raju

Source: Main Group Chemistry, Volume 8, Number 1, March 2009 , pp. 21-32(12)

Publisher: Taylor and Francis Ltd

Challenges for Drug Discovery - A Case Study of Urokinase Receptor Inhibition

Authors: Chen, Zhuo; Lin, Lin; Huai, Qing; Huang, Mingdong

Source: Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 10, December 2009 , pp. 961-967(7)

Publisher: Bentham Science Publishers

Editorial [Hot topic: In Silico Approaches in G Protein-Coupled Receptors (GPCRs) Drug Discovery: Quo Vadis? (Executive Editor: Stefano Moro)]

Author: Moro, Stefano

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 3992-3993(2)

Publisher: Bentham Science Publishers

Unraveling the Structure and Function of G Protein-Coupled Receptors Through NMR Spectroscopy

Authors: Tikhonova, Irina G.; Costanzi, Stefano

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 4003-4016(14)

Publisher: Bentham Science Publishers

Progress in Elucidating the Structural and Dynamic Character of G Protein-Coupled Receptor Oligomers for Use in Drug Discovery

Authors: Bortolato, A.; Mobarec, J. C.; Provasi, D.; Filizola, M.

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 4017-4025(9)

Publisher: Bentham Science Publishers

Customizing G Protein-Coupled Receptor Models for Structure-Based Virtual Screening

Authors: de Graaf, Chris; Rognan, Didier

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 4026-4048(23)

Publisher: Bentham Science Publishers

G Protein-Coupled Receptors: Target-Based In Silico Screening

Authors: Senderowitz, Hanoch; Marantz, Yael

Source: Current Pharmaceutical Design, Volume 15, Number 35, December 2009 , pp. 4049-4068(20)

Publisher: Bentham Science Publishers

Robust Prediction of B-Factor Profile from Sequence Using Two-Stage SVR Based on Random Forest Feature Selection

Authors: Pan, Xiao-Yong; Shen, Hong-Bin

Source: Protein and Peptide Letters, Volume 16, Number 12, December 2009 , pp. 1447-1454(8)

Publisher: Bentham Science Publishers

Structure, Function, Regulation and Polymorphism of Human Cytochrome P450 2A6

Authors: Di, Yuan M.; Chow, Vivian D.e.h-W.e.i.; Yang, Li-Ping; Zhou, Shu-Feng

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 754-780(27)

Publisher: Bentham Science Publishers

Rational structure-based drug design and optimization in the ligand-binding domain of the glucocorticoid receptor-α

Authors: Onnis, Valeria; Kinsella, Gemma K; Carta, Giorgio; Fayne, Darren; Lloyd, David G

Source: Future Medicinal Chemistry, Volume 1, Number 2, May 2009 , pp. 345-359(15)

Publisher: Future Science

Radiation-induced defects in quartz: a multifrequency EPR study and DFT modelling of new peroxy radicals

Authors: Pan, Yuanming; Nilges, M.J.; Mashkovtsev, R.I.

Source: Mineralogical Magazine, Volume 73, Number 4, August 2009 , pp. 519-535(17)

Publisher: Mineralogical Society

Three-Dimensional Protein-Ligand Interaction Scaling of Two-Dimensional Fingerprints

Authors: Tan, Lu; Vogt, Martin; Bajorath, Jürgen

Source: Chemical Biology & Drug Design, Volume 74, Number 5, November 2009 , pp. 449-456(8)

Publisher: Blackwell Publishing

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

Authors: Zhai, Rong; Rizzi, Menico; Garavaglia, Silvia

Source: Cellular and Molecular Life Sciences CMLS, Volume 66, Number 17, September 2009 , pp. 2805-2818(14)

Publisher: Springer