Search Results

Altered expression of CYP in TSOD mice: a model of type 2 diabetes and obesity

Authors: Kudo, T.; Shimada, T.; Toda, T.; Igeta, S.; Suzuki, W.; Ikarashi, N.; Ochiai, W.; Ito, K.; Aburada, M.; Sugiyama, K.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 889-902(14)

Publisher: Informa Healthcare

Effects of Escherichia coli lipopolysaccharide on the metformin pharmacokinetics in rats

Authors: Cho, Y. K.; Choi, Y. H.; Kim, S. H.; Lee, M. G.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 946-954(9)

Publisher: Informa Healthcare

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

Authors: Greenblatt, David J.; Peters, Diane E.; Oleson, Lauren E.; Harmatz, Jerold S.; MacNab, Malcolm W.; Berkowitz, Noah; Zinny, Miguel A.; Court, Michael H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 920-927(8)

Publisher: Blackwell Publishing

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A

Authors: Turpault, Sandrine; Brian, William; Van Horn, Robert; Santoni, Alix; Poitiers, Franck; Donazzolo, Yves; Boulenc, Xavier

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 928-935(8)

Publisher: Blackwell Publishing

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans

Authors: Mukonzo, Jackson K.; Röshammar, Daniel; Waako, Paul; Andersson, Maria; Fukasawa, Takashi; Milani, Lili; Svensson, Jan Olof; Ogwal-Okeng, Jasper; Gustafsson, Lars L.; Aklillu, Eleni

Source: British Journal of Clinical Pharmacology, Volume 68, Number 5, November 2009 , pp. 690-699(10)

Publisher: Blackwell Publishing

Roles of Different CYP Enzymes in the Formation of Specific Fluvastatin Metabolites by Human Liver Microsomes

Authors: Toda, Takaki; Eliasson, Erik; Ask, Birgitta; Inotsume, Nobuo; Rane, Anders

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 5, November 2009 , pp. 327-332(6)

Publisher: Blackwell Publishing

Effects of rifampicin on the pharmacokinetics of roflumilast and roflumilast N-oxide in healthy subjects

Authors: Nassr, Nassr; Huennemeyer, Andreas; Herzog, Rolf; von Richter, Oliver; Hermann, Robert; Koch, Manuela; Duffy, Kevin; Zech, Karl; Lahu, Gezim

Source: British Journal of Clinical Pharmacology, Volume 68, Number 4, October 2009 , pp. 580-587(8)

Publisher: Blackwell Publishing

Delivery of high levels of anti-proliferative nucleoside triphosphates to CYP3A-expressing cells as a potential treatment for hepatocellular carcinoma

Authors: MacKenna, Deidre; Montag, Annika; Boyer, Serge; Linemeyer, David; Erion, Mark

Source: Cancer Chemotherapy and Pharmacology, Volume 64, Number 5, October 2009 , pp. 981-991(11)

Publisher: Springer

In vitro model for the prediction of clinical CYP3A4 induction using HepaRG cells

Authors: Kaneko, A.; Kato, M.; Sekiguchi, N.; Mitsui, T.; Takeda, K.; Aso, Y.

Source: Xenobiotica, Volume 39, Number 11, November 2009 , pp. 803-810(8)

Publisher: Informa Healthcare

Clinical Pharmacokinetics and Pharmacodynamics of Etravirine

Authors: Schöller-Gyüre, Monika; Kakuda, Thomas N.; Raoof, Araz; >Goedele De Smedt,; Hoetelmans, Richard M.W.

Source: Clinical Pharmacokinetics, Volume 48, Number 9, 1 September 2009 , pp. 561-574(14)

Publisher: Adis International

Immunotherapy in Elderly Transplant Recipients: A Guide to Clinically Significant Drug Interactions

Author: Kuypers, Dirk R.J.

Source: Drugs & Aging, Volume 26, Number 9, 1 September 2009 , pp. 715-737(23)

Publisher: Adis International

The effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole

Authors: Kovarik, John M.; Huang, Hsun-Lun A.; Slade, Alan; Sfikas, Nikos; Chandler, Patricia A.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 3, September 2009 , pp. 381-385(5)

Publisher: Blackwell Publishing

Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady-state in Korean epileptic patients

Authors: Park, P.-W.; Seo, Y. H.; Ahn, J. Y.; Kim, K.-A.; Park, J.-Y.

Source: Journal of Clinical Pharmacy & Therapeutics, Volume 34, Number 5, October 2009 , pp. 569-574(6)

Publisher: Blackwell Publishing

Preconditioned Cell Array Optimized for a Three-Dimensional Culture of Hepatocytes

Authors: Miyamoto, Yoshitaka; Ikeya, Takeshi; Enosawa, Shin

Source: Cell Transplantation, Volume 18, Numbers 5-6, 2009 , pp. 677-681(5)

Publisher: Cognizant Communication Corporation

Comparison of Pharmacokinetics of Cyclosporine A in Cadaveric and Living- Related Renal Transplant Recipients and in an Experimental Rat Model of Renal Failure

Authors: Sugioka, Nobuyuki; Fujimoto, Katsukuni; Tanaka, Yuka; Fukushima, Keizo; Ito, Yukako; Kokuhu, Takatoshi; Okamoto, Masahiko; Yoshimura, Norio; Takada, Kanji

Source: Drug Metabolism Letters, Volume 3, Number 3, August 2009 , pp. 152-161(10)

Publisher: Bentham Science Publishers

The In Vivo Response of Novel Buprenorphine Metabolites, M1 and M3, to Antiretroviral Inducers and Inhibitors of Buprenorphine Metabolism

Authors: Moody, David E.; Chang, Yan; Huang, Wei; McCance-Katz, Elinore F.

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 3, September 2009 , pp. 211-215(5)

Publisher: Blackwell Publishing

Modulation of androgen and estrogen receptor expression by antiepileptic drugs and steroids in hippocampus of patients with temporal lobe epilepsy

Authors: Killer, Nina; Hock, Monika; Gehlhaus, Marcel; Capetian, Philipp; Knoth, Rolf; Pantazis, Georgios; Volk, Benedikt; Meyer, Ralf P.

Source: Epilepsia, Volume 50, Number 8, August 2009 , pp. 1875-1890(16)

Publisher: Blackwell Publishing

Gefitinib-phenytoin interaction is not correlated with the ¹⁴C-erythromycin breath test in healthy male volunteers

Authors: Chhun, Stephanie; Verstuyft, Celine; Rizzo-Padoin, Nathalie; Simoneau, Guy; Becquemont, Laurent; Peretti, Ilana; Swaisland, Alan; Wortelboer, Robert; Bergmann, Jean Francois; Mouly, Stephane

Source: British Journal of Clinical Pharmacology, Volume 68, Number 2, August 2009 , pp. 226-237(12)

Publisher: Blackwell Publishing

Pharmacogenomics of CYP3A: considerations for HIV treatment

Authors: Lakhman, Sukhwinder S; Ma, Qing; Morse, Gene D

Source: Pharmacogenomics, Volume 10, Number 8, August 2009 , pp. 1323-1339(17)

Publisher: Future Medicine

Cocktail-substrate assay system for mechanism-based inhibition of CYP2C9, CYP2D6, and CYP3A using human liver microsomes at an early stage of drug development

Authors: Mori, K.; Hashimoto, H.; Takatsu, H.; Tsuda-Tsukimoto, M.; Kume, T.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 415-422(8)

Publisher: Informa Healthcare