Search Results

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A

Authors: Turpault, Sandrine; Brian, William; Van Horn, Robert; Santoni, Alix; Poitiers, Franck; Donazzolo, Yves; Boulenc, Xavier

Source: British Journal of Clinical Pharmacology, Volume 68, Number 6, December 2009 , pp. 928-935(8)

Publisher: Blackwell Publishing

Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis

Authors: Kim, Sang-Heon; Kim, Sang-Hoon; Bahn, Joon-Woo; Kim, Yoon-Keun; Chang, Yoon-Seok; Shin, Eun-Soon; Kim, Youn-Seup; Park, Jae-Seuk; Kim, Bo-Hyung; Jang, In-Jin; Song, Junghan; Kim, Seung-Hyun; Park, Hae-Sim; Min, Kyung-Up; Jee, Young-Koo

Source: Pharmacogenomics, Volume 10, Number 11, November 2009 , pp. 1767-1779(13)

Publisher: Future Medicine

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance: Part II

Author: Zhou, Shu-Feng

Source: Clinical Pharmacokinetics, Volume 48, Number 12, 1 December 2009 , pp. 761-804(44)

Publisher: Adis International

The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

Authors: Muschler, Eugen; Lal, Jawahar; Jetter, Alexander; Rattay, Anke; Zanger, Ulrich; Zadoyan, Gregor; Fuhr, Uwe; Kirchheiner, Julia

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 6, December 2009 , pp. 374-379(6)

Publisher: Blackwell Publishing

Editorial [Hot topic: Novel Approaches to Pharmacogenomic Investigations (Executive Editor: Kelan G. Tantisira)]

Author: Tantisira, Kelan G.

Source: Current Pharmaceutical Design, Volume 15, Number 32, November 2009 , pp. 3732-3733(2)

Publisher: Bentham Science Publishers

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

Authors: Wang, Bo; Yang, Li-Ping; Zhang, Xiao-Zhuang; Huang, Shui-Qing; Bartlam, Mark; Zhou, Shu-Feng

Source: Drug Metabolism Reviews, Volume 41, Number 4, November 2009 , pp. 573-643(71)

Publisher: Informa Healthcare

The Design and Development of Fesoterodine as a Prodrug of 5- Hydroxymethyl Tolterodine (5-HMT), the Active Metabolite of Tolterodine

Authors: Malhotra, B.; Gandelman, K.; Sachse, R.; Wood, N.; Michel, M. C.

Source: Current Medicinal Chemistry, Volume 16, Number 33, November 2009 , pp. 4481-4489(9)

Publisher: Bentham Science Publishers

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance: Part I

Author: Zhou, Shu-Feng

Source: Clinical Pharmacokinetics, Volume 48, Number 11, 1 November 2009 , pp. 689-723(35)

Publisher: Adis International

Pharmacogenomics - Implications in the Development of HIV-Associated Brain Disease

Authors: Nolting, Thorsten; Arendt, Gabriele

Source: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Cu, Volume 8, Number 2, June 2009 , pp. 164-168(5)

Publisher: Bentham Science Publishers

Pharmacogenomics and therapeutic strategies for dementia

Author: Cacabelos, Ramón

Source: Expert Review of Molecular Diagnostics, Volume 9, Number 6, September 2009 , pp. 567-611(45)

Publisher: Expert Reviews

Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy

Authors: Ververs, F.F. Tessa; Voorbij, Heronimus A.M.; Zwarts, Petra; Belitser, Svetlana V.; Egberts, Toine C.G.; Visser, Gerard H.A.; Schobben, Alfred F.A.M.

Source: Clinical Pharmacokinetics, Volume 48, Number 10, 1 October 2009 , pp. 677-683(7)

Publisher: Adis International

Discovery of 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: Integrated Drug-Design and Structure-Activity Relationships for Orally Potent, Metabolically Stable and Potential-Risk Reduced Novel Non-Peptide Nociceptin/Orphanin FQ Receptor Agonist as Antianxiety Drug

Authors: Hayashi, Shigeo; Hirao, Akiko; Nakamura, Hiroshi; Yamamura, Kenzo; Mizuno, Kunihiko; Yamashita, Hiroyo

Source: Chemical Biology & Drug Design, Volume 74, Number 4, October 2009 , pp. 369-381(13)

Publisher: Blackwell Publishing

Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix Extracts on Cytochrome P450 Activities in Healthy Volunteers

Authors: Yi, SoJeong; Cho, Joo-Youn; Lim, Kyoung Soo; Kim, Kyu-pyo; Kim, JaeWoo; Kim, Bo-Hyung; Hong, Jang-hee; Jang, In-Jin; Shin, Sang-Goo; Yu, Kyung-Sang

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 4, October 2009 , pp. 249-256(8)

Publisher: Blackwell Publishing

Metabolism of Loratadine and Further Characterization of Its In Vitro Metabolites

Authors: Ghosal, Anima; Gupta, Samir; Ramanathan, Ragu; Yuan, Yuan; Lu, Xiaowen; Su, Ai D.u.e.n.I.r.i.s.; Alvarez, Narciso; Zbaida, Shmuel; Chowdhury, Swapan K.; Alton, Kevin B.

Source: Drug Metabolism Letters, Volume 3, Number 3, August 2009 , pp. 162-170(9)

Publisher: Bentham Science Publishers

Implementation of CYP2D6 genotyping in psychiatry

Authors: Loovers, Harriët M; van der Weide, Jan

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 9, September 2009 , pp. 1065-1077(13)

Publisher: Informa Healthcare

The Impact of CYP2D6 Genetic Polymorphisms on Postoperative Morphine Consumption

Authors: Candiotti, Keith A.; Yang, Zongqi; Rodriguez, Yiliam; Crescimone, Andres; Sanchez, Greys C.; Takacs, Peter; Medina, Carlos; Zhang, Yanping; Liu, Huanliang; Gitlin, Melvin C.

Source: Pain Medicine, Volume 10, Number 5, July/August 2009 , pp. 799-805(7)

Publisher: Blackwell Publishing

Variation in the CYP2D6 gene is associated with a lower serum sodium concentration in patients on antidepressants

Authors: Kwadijk-de Gijsel, Sonja; Bijl, Monique J.; Visser, Loes E.; van Schaik, Ron H. N.; Hofman, Albert; Vulto, Arnold G.; van Gelder, Teun; Ch. Stricker, Bruno H.

Source: British Journal of Clinical Pharmacology, Volume 68, Number 2, August 2009 , pp. 221-225(5)

Publisher: Blackwell Publishing

Gefitinib-phenytoin interaction is not correlated with the ¹⁴C-erythromycin breath test in healthy male volunteers

Authors: Chhun, Stephanie; Verstuyft, Celine; Rizzo-Padoin, Nathalie; Simoneau, Guy; Becquemont, Laurent; Peretti, Ilana; Swaisland, Alan; Wortelboer, Robert; Bergmann, Jean Francois; Mouly, Stephane

Source: British Journal of Clinical Pharmacology, Volume 68, Number 2, August 2009 , pp. 226-237(12)

Publisher: Blackwell Publishing

Fragment-based prediction of cytochromes P450 2D6 and 1A2 inhibition by recursive partitioning

Authors: Burton, J.; Danloy, E.; Vercauteren, D. P.

Source: SAR and QSAR in Environmental Research, Volume 20, Numbers 3-4, April 2009 , pp. 185-205(21)

Publisher: Taylor and Francis Ltd

Substrate Specificity, Inhibitors and Regulation of Human Cytochrome P450 2D6 and Implications in Drug Development

Authors: Zhou, Shu-Feng; Liu, Jun-Ping; Lai, Xin-Sheng

Source: Current Medicinal Chemistry, Volume 16, Number 21, July 2009 , pp. 2661-2805(145)

Publisher: Bentham Science Publishers