Search Results

C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes

Authors: Zhang, Y.-Y.; Liu, Y.; Zhang, J.-W.; Ge, G.-B.; Liu, H.-X.; Wang, L.-M.; Sun, J.; Yang, L.

Source: Xenobiotica, Volume 39, Number 12, December 2009 , pp. 903-914(12)

Publisher: Informa Healthcare

The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

Authors: Muschler, Eugen; Lal, Jawahar; Jetter, Alexander; Rattay, Anke; Zanger, Ulrich; Zadoyan, Gregor; Fuhr, Uwe; Kirchheiner, Julia

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 6, December 2009 , pp. 374-379(6)

Publisher: Blackwell Publishing

Roles of Different CYP Enzymes in the Formation of Specific Fluvastatin Metabolites by Human Liver Microsomes

Authors: Toda, Takaki; Eliasson, Erik; Ask, Birgitta; Inotsume, Nobuo; Rane, Anders

Source: Basic & Clinical Pharmacology & Toxicology, Volume 105, Number 5, November 2009 , pp. 327-332(6)

Publisher: Blackwell Publishing

The Transcriptional Regulation of the Human CYP2C Genes

Authors: Chen, Yuping; Goldstein, Joyce A.

Source: Current Drug Metabolism, Volume 10, Number 6, July 2009 , pp. 567-578(12)

Publisher: Bentham Science Publishers

Metabolism of Loratadine and Further Characterization of Its In Vitro Metabolites

Authors: Ghosal, Anima; Gupta, Samir; Ramanathan, Ragu; Yuan, Yuan; Lu, Xiaowen; Su, Ai D.u.e.n.I.r.i.s.; Alvarez, Narciso; Zbaida, Shmuel; Chowdhury, Swapan K.; Alton, Kevin B.

Source: Drug Metabolism Letters, Volume 3, Number 3, August 2009 , pp. 162-170(9)

Publisher: Bentham Science Publishers

Bisphosphonate-related osteonecrosis: genetic and acquired risk factors

Authors: Sarasquete, ME; González, M; San Miguel, JF; García-Sanz, R

Source: Oral Diseases, Volume 15, Number 6, September 2009 , pp. 382-387(6)

Publisher: Blackwell Publishing

Pharmacokinetic studies of enantiomers of ibuprofen and its chiral metabolites in humans with different variants of genes coding CYP2C8 and CYP2C9 isoenzymes

Authors: Karaźniewicz-łada, M.; łuczak, M.; Główka, F.

Source: Xenobiotica, Volume 39, Number 6, June 2009 , pp. 476-485(10)

Publisher: Informa Healthcare

In vitro and in vivo assessment of the effect of dalcetrapib on a panel of CYP substrates

Authors: Derks, Michael; Fowler, Stephen; Kuhlmann, Olaf

Source: Current Medical Research and Opinion, Volume 25, Number 4, April 2009 , pp. 891-902(12)

Publisher: Informa Healthcare

Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology

Authors: Kaspera, Rüdiger; Totah, Rheem A

Source: Expert Opinion on Drug Metabolism and Toxicology, Volume 5, Number 7, July 2009 , pp. 757-771(15)

Publisher: Informa Healthcare

Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel

Authors: Zhang, Y. -Y.; Liu, Y.; Zhang, J. -W.; Ge, G. -B.; Wang, L. -M.; Sun, J.; Yang, L.

Source: Xenobiotica, Volume 39, Number 4, April 2009 , pp. 283-292(10)

Publisher: Informa Healthcare

Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design

Authors: Perloff, E. S.; Mason, A. K.; Dehal, S. S.; Blanchard, A. P.; Morgan, L.; Ho, T.; Dandeneau, A.; Crocker, R. M.; Chandler, C. M.; Boily, N.; Crespi, C. L.; Stresser, D. M.

Source: Xenobiotica, Volume 39, Number 2, February 2009 , pp. 99-112(14)

Publisher: Informa Healthcare

Pharmacogenetic Studies of Paclitaxel in the Treatment of Ovarian Cancer

Authors: Gréen, Henrik; Söderkvist, Peter; Rosenberg, Per; Mirghani, Rajaa A.; Rymark, Per; Lundqvist, Elisabeth Åvall; Peterson, Curt

Source: Basic & Clinical Pharmacology & Toxicology, Volume 104, Number 2, February 2009 , pp. 130-137(8)

Publisher: Blackwell Publishing

Inflammatory reactions and drug response: importance of cytochrome P450 and membrane transporters

Authors: Dumais, Guillaume; Iovu, Mirela; du Souich, Patrick

Source: Expert Review of Clinical Pharmacology, Volume 1, Number 5, September 2008 , pp. 627-647(21)

Publisher: Expert Reviews

Pharmacogenetic tools for malaria and TB in the Developing World

Authors: Ferreira, Pedro Eduardo; Cavaco, Isa; Gil, José Pedro

Source: Personalized Medicine, Volume 5, Number 6, November 2008 , pp. 627-639(13)

Publisher: Future Medicine

Amodiaquine pharmacogenetics

Author: Gil, Jose Pedro

Source: Pharmacogenomics, Volume 9, Number 10, October 2008 , pp. 1385-1390(6)

Publisher: Future Medicine

Analyses of CYP2C in Porcine Microsomes

Authors: Skaanild, Mette T.; Friis, Christian

Source: Basic & Clinical Pharmacology & Toxicology, Volume 103, Number 5, November 2008 , pp. 487-492(6)

Publisher: Blackwell Publishing

Editorial

Author: Prakash, Chandra

Source: Drug Metabolism Letters, Volume 2, Number 3, August 2008 , pp. 151-152(2)

Publisher: Bentham Science Publishers

Troglitazone Thiol Adduct Formation in Human Liver Microsomes: Enzyme Knietics and Reaction Phenotyping

Authors: Gan, Jinping; Qu, Qinling; He, Bing; Shyu, Wen C.; Rodrigues, A. D.; He, Kan

Source: Drug Metabolism Letters, Volume 2, Number 3, August 2008 , pp. 184-189(6)

Publisher: Bentham Science Publishers

Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin

Authors: Neuvonen, Pertti J.; Backman, Janne T.; Niemi, Mikko

Source: Clinical Pharmacokinetics, Volume 47, Number 7, 2008 , pp. 463-474(12)

Publisher: Adis International

Heterotropic Cooperativity in Oxidation Mediated by Cytochrome P450

Authors: Niwa, Toshiro; Murayama, Norie; Yamazaki, Hiroshi

Source: Current Drug Metabolism, Volume 9, Number 5, June 2008 , pp. 453-462(10)

Publisher: Bentham Science Publishers