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Insilico analysis of homocamptothecin (hCPT) analogues for anti-tumour activity

Authors: Vadwai, Viral; Devaraj, Shine

Source: International Journal of Bioinformatics Research and Applications, Volume 5, Number 6, 29 October 2009 , pp. 603-615(13)

Publisher: Inderscience Publishers

Editorial [Special Board Members Issue]

Author: Prakash, Chandra

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 659-660(2)

Publisher: Bentham Science Publishers

Pharmacokinetics of Biotech Drugs: Peptides, Proteins and Monoclonal Antibodies

Author: Lin, Jiunn H.

Source: Current Drug Metabolism, Volume 10, Number 7, September 2009 , pp. 661-691(31)

Publisher: Bentham Science Publishers

Conference Report: Update on ADMET

Author: Dearden, John C

Source: Future Medicinal Chemistry, Volume 1, Number 2, May 2009 , pp. 249-251(3)

Publisher: Future Science

Editorial

Author: Reitz, Allen B.

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 11, August 2009 , pp. 964-964(1)

Publisher: Bentham Science Publishers

ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery

Authors: Caldwell, Gary W.; Yan, Zhengyin; Tang, Weimin; Dasgupta, Malini; Hasting, Becki

Source: Current Topics in Medicinal Chemistry, Volume 9, Number 11, August 2009 , pp. 965-980(16)

Publisher: Bentham Science Publishers

Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties

Authors: Hegedűs, C; Özvegy-Laczka, C; Apáti, Á; Magócsi, M; Német, K; Őrfi, L; Kéri, G; Katona, M; Takáts, Z; Váradi, A; Szakács, G; Sarkadi, B

Source: British Journal of Pharmacology, Volume 158, Number 4, October 2009 , pp. 1153-1164(12)

Publisher: Blackwell Publishing

Psychological distress and mental health treatment among persons with and without active duty military experience, Behavioral Risk Factor Surveillance System, United States, 2007

Authors: Safran, Marc; Strine, Tara; Dhingra, Satvinder; Berry, Joyce; Manderscheid, Ron; Mokdad, Ali

Source: International Journal of Public Health, Volume 54, Supplement 1, June 2009 , pp. 61-67(7)

Publisher: Springer

Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally bioavailable systemic Hedgehog signalling pathway inhibitor

Authors: Wong, H.; Chen, J.Z.; Chou, B.; Halladay, J.S.; Kenny, J.R.; La, H.; Marsters, J.C.; Plise, E.; Rudewicz, P.J.; Robarge, K.; Shin, Y.; Wong, S.; Zhang, C.; Khojasteh, S.C.

Source: Xenobiotica, Volume 39, Number 11, November 2009 , pp. 850-861(12)

Publisher: Informa Healthcare

Importance of Influx and Efflux Systems and Xenobiotic Metabolizing Enzymes in Intratumoral Disposition of Anticancer Agents

Author: Rochat, B.

Source: Current Cancer Drug Targets, Volume 9, Number 5, August 2009 , pp. 652-674(23)

Publisher: Bentham Science Publishers

Multivariate Linear Regression Models Based on ADME Descriptors and Predictions of ADMET Profile for Structurally Diverse Thermolysin Inhibitors

Authors: Khan, Mahmud T.H.; Sylte, Ingebrigt

Source: Letters in Drug Design & Discovery, Volume 6, Number 6, September 2009 , pp. 428-436(9)

Publisher: Bentham Science Publishers

Variation of Drug Kinetics in Pregnancy

Authors: Pavek, Petr; Ceckova, Martina; Staud, Frantisek

Source: Current Drug Metabolism, Volume 10, Number 5, June 2009 , pp. 520-529(10)

Publisher: Bentham Science Publishers

Site of metabolism prediction for six biotransformations mediated by cytochromes P450

Authors: Zheng, Mingyue; Luo, Xiaomin; Shen, Qiancheng; Wang, Yong; Du, Yun; Zhu, Weiliang; Jiang, Hualiang

Source: Bioinformatics, Volume 25, Number 10, 15 May 2009 , pp. 1251-1258(8)

Publisher: Oxford University Press

Fragment-based prediction of cytochromes P450 2D6 and 1A2 inhibition by recursive partitioning

Authors: Burton, J.; Danloy, E.; Vercauteren, D. P.

Source: SAR and QSAR in Environmental Research, Volume 20, Numbers 3-4, April 2009 , pp. 185-205(21)

Publisher: Taylor and Francis Ltd

Drug-Like Property Concepts in Pharmaceutical Design

Authors: Di, Li; Kerns, Edward H.; Carter, Guy T.

Source: Current Pharmaceutical Design, Volume 15, Number 19, July 2009 , pp. 2184-2194(11)

Publisher: Bentham Science Publishers

Translational strategies to implement personalized medicine: rheumatoid arthritis examples

Author: Littman, Bruce H

Source: Personalized Medicine, Volume 6, Number 4, July 2009 , pp. 429-437(9)

Publisher: Future Medicine

Determination of Human Serum α1-Acid Glycoprotein and Albumin Binding of Various Marketed and Preclinical Kinase Inhibitors

Authors: Zsila, Ferenc; Fitos, Ilona; Bencze, Gyula; Keri, Gyorgy; Orfi, Laszlo

Source: Current Medicinal Chemistry, Volume 16, Number 16, June 2009 , pp. 1964-1977(14)

Publisher: Bentham Science Publishers

Advances in the Integration of Drug Metabolism into the Lead Optimization Paradigm

Author: Korfmacher, Walter A.

Source: Mini Reviews in Medicinal Chemistry, Volume 9, Number 6, June 2009 , pp. 703-716(14)

Publisher: Bentham Science Publishers

Edtiorial [Hot Topic: In Silico ADME/Tox Models: Progress and Challenges (Guest Editors: Robert K. DeLisle and David J. Diller)]

Authors: DeLisle, Robert K.; Diller, David J.

Source: Current Computer - Aided Drug Design, Volume 5, Number 2, June 2009 , pp. 69-70(2)

Publisher: Bentham Science Publishers

Computational Models for Central Nervous System Penetration

Author: Klon, Anthony E.

Source: Current Computer - Aided Drug Design, Volume 5, Number 2, June 2009 , pp. 71-89(19)

Publisher: Bentham Science Publishers