Search Results

Key role of topoisomerase I inhibitors in the treatment of recurrent and refractory epithelial ovarian carcinoma

Authors: Wethington, Stephanie L; Wright, Jason D; Herzog, Thomas J

Source: Expert Review of Anticancer Therapy, Volume 8, Number 5, May 2008 , pp. 819-831(13)

Publisher: Expert Reviews

Effect of pH and human serum albumin on the cytotoxicity of a glucuronide prodrug of 9-aminocamptothecin

Authors: Prijovich, Zeljko; Leu, Yu-Lin; Roffler, Steve

Source: Cancer Chemotherapy and Pharmacology, Volume 60, Number 1, June 2007 , pp. 7-17(11)

Publisher: Springer

Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes

Authors: Zamboni, William; Ramanathan, Ramesh; McLeod, Howard; Mani, Sridhar; Potter, Douglas; Strychor, Sandra; Maruca, Lauren; King, Cristi; Jung, Laura; Parise, Robert; Egorin, Merrill; Davis, Todd; Marsh, Sharon

Source: Investigational New Drugs, Volume 24, Number 5, September 2006 , pp. 393-401(9)

Publisher: Springer

Alternative administration of camptothecin analogues

Authors: Glaberman, Ursa; Rabinowitz, Ian; Verschraegen, Claire F

Source: Expert Opinion on Drug Delivery, Volume 2, Number 2, 1 March 2005 , pp. 323-333(11)

Publisher: Informa Healthcare

Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck

Author: Barbara A Murphy

Source: Expert Opinion on Pharmacotherapy, Volume 6, Number 1, 1 January 2005 , pp. 85-92(8)

Publisher: Informa Healthcare

Plasma and cerebrospinal fluid pharmacokinetic study of BNP1350 in nonhuman primates

Authors: Thompson, Patrick; Berg, Stacey; Aleksic, Alexander; Kerr, Jody; McGuffey, Leticia; Dauser, Robert; Nuchtern, Jed; Hausheer, Fred; Blaney, Susan

Source: Cancer Chemotherapy and Pharmacology, Volume 53, Number 6, June 2004 , pp. 527-532(6)

Publisher: Springer

Pharmacokinetic studies of 9-nitrocamptothecin on intermittent and continuous schedules of administration in patients with solid tumors

Authors: Jung, Laura; Ramanathan, Ramesh; Egorin, Merrill; Jin, Ruzhi; Belani, Chandra; Potter, Douglas; Strychor, Sandra; Trump, Donald; Walko, Christine; Fakih, Marwan; Zamboni, William

Source: Cancer Chemotherapy and Pharmacology, Volume 54, Number 6, December 2004 , pp. 487-496(10)

Publisher: Springer

9-Aminocamptothecin (9-AC) given as a 120-hour continuous infusion in patients with advanced adenocarcinomas of the stomach and gastroesophageal junction: A phase II trial of the University of Chicago phase II consortium

Authors: Kindler, Hedy; Avadhani, Anjali; Wade-Oliver, Kurombi; Karrison, Theodore; Mani, Sridhar; Vokes, Everett

Source: Investigational New Drugs, Volume 22, Number 3, August 2004 , pp. 323-327(5)

Publisher: Springer

Development of a bioanalytical liquid chromatography method for quantitation of 9-nitrocamptothecin in human plasma

Authors: Gounder M.K.; Sun S.-L.; Sands H.; Lin Y.; Shih W.J.; Gu Z.; Charles-Williams S.; Roychowdhury M.; Rajendra R.; Rubin E.H.

Source: Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, Volume 799, Number 1, 5 January 2004 , pp. 63-72(10)

Publisher: Elsevier

Stability of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in the presence of human serum albumin

Authors: Prijovich Z.M.; Leu Y.-L.; Roffler S.R.

Source: Biochemical Pharmacology, Volume 66, Number 7, 1 October 2003 , pp. 1181-1187(7)

Publisher: Elsevier

Intravenous administration of 9-aminocamptothecin to dogs with lymphoma

Authors: Moore A.S.; Imondi A.R.; de Souza P.L.; Wood C.A.

Source: Veterinary and Comparative Oncology, Volume 1, Number 2, June 2003 , pp. 86-93(8)

Publisher: Blackwell Publishing

Camptothecin analogues and vinblastine in the treatment of renal cell carcinoma: an in vivo study using a human orthotopic renal cancer xenograft

Authors: El-Galley R.; Keane T.E.; Sun C.

Source: Urologic Oncology: Seminars and Original Investigations, Volume 21, Number 1, January 2003 , pp. 49-57(9)

Publisher: Elsevier

Camptothecins: A Review of Their Chemotherapeutic Potential

Authors: Ulukan H.; Swaan P.W.

Source: Drugs, Volume 62, Number 14, 2002 , pp. 2039-2057(19)

Publisher: Adis International

Novel 20-Carbonate Linked Prodrugs of Camptothecin and 9-Aminocamptothecin Designed for Activation by Tumour-Associated Plasmin

Authors: de Groot F.M.H.; Busscher G.F.; Aben R.W.M.; Scheeren H.W.

Source: Bioorganic and Medicinal Chemistry Letters, Volume 12, Number 17, 2 September 2002 , pp. 2371-2376(6)

Publisher: Elsevier

Determination of 9-nitrocamptothecin and its metabolite 9-aminocamptothecin in human plasma using high-performance liquid chromatography with ultraviolet and fluorescence detection

Authors: Schoemaker N.E.; Rosing H.; Jansen S.; Schoffski P.; Rizzo J.; Schellens J.H.M.; Beijnen J.H.

Source: Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, Volume 775, Number 2, 5 August 2002 , pp. 231-237(7)

Publisher: Elsevier

Design of novel bioconjugates for targeted drug delivery

Authors: Lu Z.-R.; Shiah J.-G.; Sakuma S.; Kopeckova P.; Kopecek J.

Source: Journal of Controlled Release, Volume 78, Number 1, 17 January 2002 , pp. 165-173(9)

Publisher: Elsevier

Analytical approaches for traditional Chinese medicines exhibiting antineoplastic activity

Author: Tsai T.-H.

Source: Journal of Chromatography B: Biomedical Sciences and Applications, Volume 764, Number 1, 25 November 2001 , pp. 27-48(22)

Publisher: Elsevier

Phase II Trial of 9-Aminocamptothecin as a 72-h Infusion in Cutaneous T-Cell Lymphoma

Authors: Argiris A.; Heald P.; Kuzel T.; Foss F.M.; DiStasio S.; Cooper D.L.; Arbuck S.; Murren J.R.

Source: Investigational New Drugs, Volume 19, Number 4, November 2001 , pp. 321-326(6)

Publisher: Springer

A Phase II Trial of 9-Aminocaptothecin (9-AC) as a 120-h Infusion in Patients with Non-Small Cell Lung Cancer

Authors: Vokes E.E.; Gordon G.S.; Rudin C.M.; Mauer A.M.; Watson S.; Krauss S.; Arrieta R.; Golomb H.M.; Hoffman P.C.

Source: Investigational New Drugs, Volume 19, Number 4, November 2001 , pp. 329-333(5)

Publisher: Springer

Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin

Authors: Sakuma S.; Lu Z.-R.; Kopeckova P.; Kopecek J.

Source: Journal of Controlled Release, Volume 75, Number 3, 10 August 2001 , pp. 365-379(15)

Publisher: Elsevier