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A hundred years in the elucidation of the structures of natural products

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The development in the strategies for elucidating the structures of natural products from 1916 to 2016 are reviewed revealing the transition from chemical to spectroscopic methods and using examples drawn from the chemistry of terpenoids and steroids.
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Keywords: CHEMICAL DEGRADATION; SPECTROSCOPY; STEROIDS; TERPENES

Document Type: Review Article

Affiliations: University of Sussex

Publication date: 01 March 2017

This article was made available online on 06 March 2017 as a Fast Track article with title: "A hundred years in the elucidation of the structures of natural products".

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  • SCIENCE PROGRESS has for over 100 years been a highly regarded review publication in science, technology and medicine. Its objective is to excite the readers' interest in areas with which they may not be fully familiar but which could facilitate their interest, or even activity, in a cognate field. Science Progress commissions world authorities to contribute articles on the most interesting, important and meaningful topics - ranging from cosmology to the environment - and ensures that they are presented for the most effective use of those in both academia and industry.

    Truly, Science Progress publishes an eclectic mix of articles that no library can afford to be without.

    Cover image: Plastic debris washed-up on a river bank. The manufacture and use of different types of plastic, and the effects of pollution by these materials are discussed in the article on pages 207–260. Credit: By igorstevanovic/Shutterstock.com.

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