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Free Content The impact of Xpert® MTB/RIF depends on service coordination: experience in Burkina Faso

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Translating the potential of Xpert® MTB/RIF into more effective tuberculosis (TB) care and control in low-income settings is challenged by operational issues. We report the experience in introducing this technology in Burkina Faso through a centralised approach. Xpert was successfully integrated into the diagnostic algorithm of multidrug-resistant TB cases. However, barriers to Xpert use for the diagnosis of TB in vulnerable populations, such as persons living with human immunodeficiency virus infection and children, were observed, mainly due to lack of coordination between services. Lessons learnt can be exploited to optimise the roll-out of this technology at country level.
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Keywords: MDR-TB; PLHIV; childhood TB; prisoners; resource-constrained countries

Document Type: Research Article

Affiliations: 1: *National Tuberculosis Program, Ministry of Health, Ouagadougou, Burkina Faso 2: University Division of Infectious and Tropical Disease, World Health Organization (WHO) Collaborating Centre for TB/HIV Activities and for TB Elimination, University of Brescia, Brescia 3: Emerging Pathogens Unit, TB Supranational Reference laboratory, San Raffaele Scientific Institute, Milan, Italy 4: §Global TB Programme, TB/HIV and Community Engagement Unit, WHO, Geneva, Switzerland

Publication date: 01 March 2015

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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