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Tuberculosis due to drug-resistant Mycobacterium bovis in pregnancy [Case Study]

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We describe the management practices adopted in a case of pulmonary and extra-pulmonary tuberculosis caused by an isoniazid/pyrazinamide resistant strain of Mycobacterium bovis in a 26-week pregnant woman. She was initially treated with rifampin, isoniazid and ethambutol, pre-term delivery was induced and streptomycin was then added to the regimen. Screening of the new-born revealed no signs of either disease or infection. Isoniazid prophylaxis was not administered and the new-born was vaccinated and isolated from the mother for two months; however she continued to be fed with her mother's milk for the whole period.

Keywords: Mycobacterium bovis; drug resistance; pregnancy; tuberculosis

Document Type: Short Communication

Affiliations: 1: Clinic of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy 2: Laboratory of Mycobacteriology, Spedali Civili, Brescia, Italy

Publication date: 01 April 1998

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