Rapid Synthesis of Taxifolione and Taxifolial D, Two Metabolites from the Marine Alga Caulerpa taxifolia
The synthesis of two natural products - Taxifolione and Taxifolial D - isolated from the marine alga Caulerpa taxifolia invading the Mediterranean Sea was performed. Coupling reactions allowed for a rapid synthesis. The surprising Z configuration of Taxifolial D was confirmed after synthesis and comparison of each synthetic stereoisomer.
Keywords: Terpenoids; antitumor agents; cross-coupling; enynes
Document Type: Research Article
Publication date: 01 January 2009
- Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
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