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Synthesis of 5-Substituted-1,3,4-Oxadiazole-2(3H)-Thiones Under Microwave Irradiation

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A variety of 5-substituted-1,3,4-oxadiazole-2(3H)-thiones were prepared using microwave irradiation as energy source under solvent-free conditions. Reaction times were reduced from 5-14 h to 3-7 min affording high yields from corresponding acyl and aroyl hydrazides.





Keywords: 4-oxadiazolethiones; 5-substituted-1,3; microwave-assisted synthesis

Document Type: Research Article

Affiliations: H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan.

Publication date: 01 April 2006

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    The journal is essential reading for all organic chemists both in academia and industry.
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