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Fluorescence-Functionalized Magnetic Nanocomposites as Tracking and Targeting Systems: Their Preparation and Characterizations

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Based on the electrostatic interaction between carboxymethylated chitosan (CMCH) and negatively charged CdTe quantum dots, and the selective crosslinking of CMCH using glutaraldehyde(GA), we demonstrated the formation of Fe3O4/SiO2/CMCH/CdTe microspheres. The dense silicate shells of Fe3O4 nano-particles (NPs) protect the luminescence quenching from Fe3O4 NPs, so the composite microspheres have great fluorescence and emulative magnetism. These multifunctional fluorescence/magnetic microspheres lead to robust and water dispersible nanoparticle colloidosomes, and should be of great importance for diagnostics application and specific biological applications.





Keywords: Biological applications; Characterizations; Diagnostics application; Fe3O4/SiO2/CMCH/CdTe; Fluorescence; Magnetic; Multifunctional Microspheres; Preparation; Targeting; Tracking

Document Type: Research Article

Publication date: 01 August 2011

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  • Current Nanoscience publishes authoritative reviews and original research reports, written by experts in the field on all the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano- structures, synthesis, properties, assembly and devices. Applications of nanoscience in biotechnology, medicine, pharmaceuticals, physics, material science and electronics are also covered. The journal is essential to all involved in nanoscience and its applied areas.
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